| Full name: TIMP metallopeptidase inhibitor 1 | Alias Symbol: EPO | ||
| Type: protein-coding gene | Cytoband: Xp11.3 | ||
| Entrez ID: 7076 | HGNC ID: HGNC:11820 | Ensembl Gene: ENSG00000102265 | OMIM ID: 305370 |
| Drug and gene relationship at DGIdb | |||
TIMP1 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04066 | HIF-1 signaling pathway |
Expression of TIMP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TIMP1 | 7076 | 201666_at | 0.8968 | 0.2213 | |
| GSE20347 | TIMP1 | 7076 | 201666_at | 1.2823 | 0.0000 | |
| GSE23400 | TIMP1 | 7076 | 201666_at | 1.2800 | 0.0000 | |
| GSE26886 | TIMP1 | 7076 | 201666_at | 2.8268 | 0.0000 | |
| GSE29001 | TIMP1 | 7076 | 201666_at | 1.3338 | 0.0441 | |
| GSE38129 | TIMP1 | 7076 | 201666_at | 1.2939 | 0.0010 | |
| GSE45670 | TIMP1 | 7076 | 201666_at | 0.0016 | 0.9983 | |
| GSE53622 | TIMP1 | 7076 | 112377 | 1.3306 | 0.0000 | |
| GSE53624 | TIMP1 | 7076 | 112377 | 1.5405 | 0.0000 | |
| GSE63941 | TIMP1 | 7076 | 201666_at | -3.5322 | 0.0039 | |
| GSE77861 | TIMP1 | 7076 | 201666_at | 1.7546 | 0.0070 | |
| GSE97050 | TIMP1 | 7076 | A_23_P62115 | 1.5486 | 0.1134 | |
| SRP007169 | TIMP1 | 7076 | RNAseq | 2.4437 | 0.0000 | |
| SRP008496 | TIMP1 | 7076 | RNAseq | 2.3363 | 0.0000 | |
| SRP064894 | TIMP1 | 7076 | RNAseq | 1.9908 | 0.0006 | |
| SRP133303 | TIMP1 | 7076 | RNAseq | 1.4787 | 0.0000 | |
| SRP159526 | TIMP1 | 7076 | RNAseq | 1.7599 | 0.0000 | |
| SRP193095 | TIMP1 | 7076 | RNAseq | 1.9743 | 0.0000 | |
| SRP219564 | TIMP1 | 7076 | RNAseq | 2.0180 | 0.0036 | |
| TCGA | TIMP1 | 7076 | RNAseq | 0.1751 | 0.0388 |
Upregulated datasets: 15; Downregulated datasets: 1.
Survival by TIMP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TIMP1:
No record found for this gene.
Somatic mutations of TIMP1:
Generating mutation plots.
Highly correlated genes for TIMP1:
Showing top 20/1674 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TIMP1 | KRTCAP2 | 0.784207 | 3 | 0 | 3 |
| TIMP1 | ALKBH6 | 0.778487 | 3 | 0 | 3 |
| TIMP1 | GNS | 0.776775 | 9 | 0 | 9 |
| TIMP1 | FCGR3A | 0.774778 | 3 | 0 | 3 |
| TIMP1 | SUCNR1 | 0.765587 | 4 | 0 | 4 |
| TIMP1 | CALU | 0.765322 | 11 | 0 | 11 |
| TIMP1 | VCAN | 0.762954 | 13 | 0 | 12 |
| TIMP1 | LHFPL2 | 0.76175 | 12 | 0 | 12 |
| TIMP1 | PXDN | 0.75358 | 13 | 0 | 12 |
| TIMP1 | LOXL1 | 0.752879 | 12 | 0 | 12 |
| TIMP1 | PDIA5 | 0.750466 | 3 | 0 | 3 |
| TIMP1 | RAB34 | 0.748394 | 3 | 0 | 3 |
| TIMP1 | COL6A3 | 0.745251 | 13 | 0 | 12 |
| TIMP1 | CRTC2 | 0.744899 | 3 | 0 | 3 |
| TIMP1 | SPON2 | 0.744632 | 3 | 0 | 3 |
| TIMP1 | CDH11 | 0.74141 | 13 | 0 | 12 |
| TIMP1 | HEXB | 0.737817 | 11 | 0 | 11 |
| TIMP1 | RELL1 | 0.737665 | 3 | 0 | 3 |
| TIMP1 | LRRC8C | 0.736634 | 3 | 0 | 3 |
| TIMP1 | LMO1 | 0.736549 | 3 | 0 | 3 |
For details and further investigation, click here
