ACIN1

 

Full name: apoptotic chromatin condensation inducer 1 Alias Symbol: KIAA0670|fSAP152
Type: protein-coding gene Cytoband: 14q11.2
Entrez ID: 22985 HGNC ID: HGNC:17066 Ensembl Gene: ENSG00000100813 OMIM ID: 604562
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of ACIN1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 ACIN1 22985 201715_s_at 0.3618 0.5865
GSE20347 ACIN1 22985 201715_s_at 0.3135 0.0040
GSE23400 ACIN1 22985 201715_s_at 0.2797 0.0000
GSE26886 ACIN1 22985 201715_s_at -0.2363 0.1783
GSE29001 ACIN1 22985 201715_s_at 0.0631 0.8638
GSE38129 ACIN1 22985 201715_s_at 0.2233 0.0031
GSE45670 ACIN1 22985 201715_s_at 0.3406 0.0034
GSE53622 ACIN1 22985 16516 0.1200 0.0035
GSE53624 ACIN1 22985 16516 0.2683 0.0000
GSE63941 ACIN1 22985 201715_s_at 0.6478 0.0138
GSE77861 ACIN1 22985 201715_s_at 0.4527 0.0912
GSE97050 ACIN1 22985 A_23_P14389 0.3015 0.1998
SRP007169 ACIN1 22985 RNAseq 1.4051 0.0001
SRP008496 ACIN1 22985 RNAseq 1.0933 0.0002
SRP064894 ACIN1 22985 RNAseq 0.4542 0.0026
SRP133303 ACIN1 22985 RNAseq 0.2927 0.0798
SRP159526 ACIN1 22985 RNAseq 0.2813 0.3619
SRP193095 ACIN1 22985 RNAseq 0.3108 0.0065
SRP219564 ACIN1 22985 RNAseq 0.3713 0.2986
TCGA ACIN1 22985 RNAseq -0.0119 0.7721

Upregulated datasets: 2; Downregulated datasets: 0.  

 

Survival by ACIN1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of ACIN1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 ACIN1 22985 9 2 19
GSE20123 ACIN1 22985 9 2 19
GSE43470 ACIN1 22985 7 2 34
GSE46452 ACIN1 22985 17 2 40
GSE47630 ACIN1 22985 11 10 19
GSE54993 ACIN1 22985 3 11 56
GSE54994 ACIN1 22985 18 5 30
GSE60625 ACIN1 22985 0 2 9
GSE74703 ACIN1 22985 6 2 28
GSE74704 ACIN1 22985 4 1 15
TCGA ACIN1 22985 27 15 54

Total number of gains: 111; Total number of losses: 54; Total Number of normals: 323.  

 

Somatic mutations of ACIN1:

 

Generating mutation plots.

 

Highly correlated genes for ACIN1:

 

Showing top 20/741 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
ACIN1DENND30.824336303
ACIN1FKBP20.760638303
ACIN1LRP10.747823303
ACIN1EVI5L0.735844303
ACIN1GGN0.730446303
ACIN1KRTCAP20.727381403
ACIN1PRELID10.72536303
ACIN1PROX10.722991303
ACIN1FUCA20.717351404
ACIN1SNRNP2000.715987303
ACIN1SAMD10.709424505
ACIN1UNC5B0.707177303
ACIN1OPLAH0.702844303
ACIN1CCDC1240.701904403
ACIN1PSMA40.699424303
ACIN1STX50.697915303
ACIN1CHD80.69576911010
ACIN1SAMD4B0.693124404
ACIN1ELOF10.690025403
ACIN1ALG120.687318303

For details and further investigation, click here