| Full name: eukaryotic translation initiation factor 3 subunit F | Alias Symbol: eIF3-epsilon|eIF3-p47|eIF3f | ||
| Type: protein-coding gene | Cytoband: 11p15.4 | ||
| Entrez ID: 8665 | HGNC ID: HGNC:3275 | Ensembl Gene: ENSG00000175390 | OMIM ID: 603914 |
| Drug and gene relationship at DGIdb | |||
Expression of EIF3F:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | EIF3F | 8665 | 200023_s_at | -0.3745 | 0.1879 | |
| GSE20347 | EIF3F | 8665 | 200023_s_at | -0.5465 | 0.0014 | |
| GSE23400 | EIF3F | 8665 | 200023_s_at | -0.0400 | 0.6432 | |
| GSE26886 | EIF3F | 8665 | 200023_s_at | 0.2133 | 0.2731 | |
| GSE29001 | EIF3F | 8665 | 200023_s_at | -0.4609 | 0.2551 | |
| GSE38129 | EIF3F | 8665 | 200023_s_at | -0.3641 | 0.0124 | |
| GSE45670 | EIF3F | 8665 | 200023_s_at | -0.3949 | 0.0007 | |
| GSE53622 | EIF3F | 8665 | 96199 | -0.4147 | 0.0000 | |
| GSE53624 | EIF3F | 8665 | 96199 | -0.3689 | 0.0000 | |
| GSE63941 | EIF3F | 8665 | 200023_s_at | -0.2507 | 0.4443 | |
| GSE77861 | EIF3F | 8665 | 200023_s_at | -0.2279 | 0.6282 | |
| GSE97050 | EIF3F | 8665 | A_23_P142776 | -0.1586 | 0.4464 | |
| SRP007169 | EIF3F | 8665 | RNAseq | -0.3053 | 0.3630 | |
| SRP008496 | EIF3F | 8665 | RNAseq | -0.4066 | 0.0718 | |
| SRP064894 | EIF3F | 8665 | RNAseq | -0.2387 | 0.3804 | |
| SRP133303 | EIF3F | 8665 | RNAseq | -0.4086 | 0.0001 | |
| SRP159526 | EIF3F | 8665 | RNAseq | -0.7233 | 0.0013 | |
| SRP193095 | EIF3F | 8665 | RNAseq | -0.5507 | 0.0000 | |
| SRP219564 | EIF3F | 8665 | RNAseq | -0.3346 | 0.3185 | |
| TCGA | EIF3F | 8665 | RNAseq | -0.0960 | 0.0590 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by EIF3F expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of EIF3F:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | EIF3F | 8665 | 0 | 11 | 19 | |
| GSE20123 | EIF3F | 8665 | 0 | 11 | 19 | |
| GSE43470 | EIF3F | 8665 | 1 | 7 | 35 | |
| GSE46452 | EIF3F | 8665 | 7 | 5 | 47 | |
| GSE47630 | EIF3F | 8665 | 2 | 12 | 26 | |
| GSE54993 | EIF3F | 8665 | 3 | 1 | 66 | |
| GSE54994 | EIF3F | 8665 | 2 | 12 | 39 | |
| GSE60625 | EIF3F | 8665 | 0 | 0 | 11 | |
| GSE74703 | EIF3F | 8665 | 1 | 5 | 30 | |
| GSE74704 | EIF3F | 8665 | 0 | 9 | 11 | |
| TCGA | EIF3F | 8665 | 9 | 36 | 51 |
Total number of gains: 25; Total number of losses: 109; Total Number of normals: 354.
Somatic mutations of EIF3F:
Generating mutation plots.
Highly correlated genes for EIF3F:
Showing top 20/913 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| EIF3F | BRK1 | 0.752383 | 4 | 0 | 4 |
| EIF3F | GAPDH | 0.748362 | 3 | 0 | 3 |
| EIF3F | MRPL10 | 0.732405 | 3 | 0 | 3 |
| EIF3F | FBXO8 | 0.732223 | 4 | 0 | 4 |
| EIF3F | FIBIN | 0.728396 | 3 | 0 | 3 |
| EIF3F | ITGA1 | 0.72212 | 3 | 0 | 3 |
| EIF3F | TMEM218 | 0.721088 | 3 | 0 | 3 |
| EIF3F | CRLS1 | 0.720935 | 3 | 0 | 3 |
| EIF3F | UBE2D2 | 0.714881 | 3 | 0 | 3 |
| EIF3F | COX10 | 0.714 | 3 | 0 | 3 |
| EIF3F | MMGT1 | 0.713281 | 3 | 0 | 3 |
| EIF3F | GATAD1 | 0.711517 | 3 | 0 | 3 |
| EIF3F | ARID2 | 0.711396 | 3 | 0 | 3 |
| EIF3F | EP400 | 0.709567 | 3 | 0 | 3 |
| EIF3F | ZNF32 | 0.708839 | 4 | 0 | 4 |
| EIF3F | ARPC1A | 0.707279 | 3 | 0 | 3 |
| EIF3F | CDC123 | 0.703164 | 4 | 0 | 3 |
| EIF3F | PIK3C2A | 0.703162 | 10 | 0 | 9 |
| EIF3F | RNF185 | 0.702152 | 4 | 0 | 4 |
| EIF3F | CEPT1 | 0.700944 | 4 | 0 | 4 |
For details and further investigation, click here
