| Full name: GADD45G interacting protein 1 | Alias Symbol: PLINP-1|MGC4667|MGC4758|CKBBP2|PRG6|Plinp1|CRIF1|CKbetaBP2 | ||
| Type: protein-coding gene | Cytoband: 19p13.13 | ||
| Entrez ID: 90480 | HGNC ID: HGNC:29996 | Ensembl Gene: ENSG00000179271 | OMIM ID: 605162 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of GADD45GIP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GADD45GIP1 | 90480 | 212891_s_at | 0.3431 | 0.3932 | |
| GSE20347 | GADD45GIP1 | 90480 | 212891_s_at | -0.0866 | 0.6115 | |
| GSE23400 | GADD45GIP1 | 90480 | 212889_x_at | -0.1612 | 0.0000 | |
| GSE26886 | GADD45GIP1 | 90480 | 212891_s_at | 0.9702 | 0.0000 | |
| GSE29001 | GADD45GIP1 | 90480 | 212889_x_at | -0.1505 | 0.1528 | |
| GSE38129 | GADD45GIP1 | 90480 | 212891_s_at | 0.0754 | 0.6528 | |
| GSE45670 | GADD45GIP1 | 90480 | 212891_s_at | 0.2007 | 0.1381 | |
| GSE53622 | GADD45GIP1 | 90480 | 40037 | -0.3795 | 0.0000 | |
| GSE53624 | GADD45GIP1 | 90480 | 40037 | -0.0084 | 0.8334 | |
| GSE63941 | GADD45GIP1 | 90480 | 212891_s_at | 0.1952 | 0.6479 | |
| GSE77861 | GADD45GIP1 | 90480 | 212891_s_at | 0.2327 | 0.2585 | |
| GSE97050 | GADD45GIP1 | 90480 | A_33_P3273148 | -0.2406 | 0.3252 | |
| SRP007169 | GADD45GIP1 | 90480 | RNAseq | -0.2244 | 0.5247 | |
| SRP008496 | GADD45GIP1 | 90480 | RNAseq | -0.0620 | 0.7741 | |
| SRP064894 | GADD45GIP1 | 90480 | RNAseq | 1.5353 | 0.0028 | |
| SRP133303 | GADD45GIP1 | 90480 | RNAseq | 0.2925 | 0.1024 | |
| SRP159526 | GADD45GIP1 | 90480 | RNAseq | 0.1776 | 0.4441 | |
| SRP193095 | GADD45GIP1 | 90480 | RNAseq | -0.1255 | 0.4653 | |
| SRP219564 | GADD45GIP1 | 90480 | RNAseq | 0.5819 | 0.2075 | |
| TCGA | GADD45GIP1 | 90480 | RNAseq | 0.1814 | 0.0044 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by GADD45GIP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GADD45GIP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GADD45GIP1 | 90480 | 4 | 2 | 24 | |
| GSE20123 | GADD45GIP1 | 90480 | 3 | 1 | 26 | |
| GSE43470 | GADD45GIP1 | 90480 | 2 | 6 | 35 | |
| GSE46452 | GADD45GIP1 | 90480 | 47 | 1 | 11 | |
| GSE47630 | GADD45GIP1 | 90480 | 4 | 7 | 29 | |
| GSE54993 | GADD45GIP1 | 90480 | 16 | 3 | 51 | |
| GSE54994 | GADD45GIP1 | 90480 | 8 | 13 | 32 | |
| GSE60625 | GADD45GIP1 | 90480 | 9 | 0 | 2 | |
| GSE74703 | GADD45GIP1 | 90480 | 2 | 4 | 30 | |
| GSE74704 | GADD45GIP1 | 90480 | 0 | 1 | 19 | |
| TCGA | GADD45GIP1 | 90480 | 17 | 12 | 67 |
Total number of gains: 112; Total number of losses: 50; Total Number of normals: 326.
Somatic mutations of GADD45GIP1:
Generating mutation plots.
Highly correlated genes for GADD45GIP1:
Showing top 20/83 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GADD45GIP1 | PPY | 0.753727 | 3 | 0 | 3 |
| GADD45GIP1 | SCYL1 | 0.694435 | 3 | 0 | 3 |
| GADD45GIP1 | TXNRD2 | 0.688303 | 3 | 0 | 3 |
| GADD45GIP1 | AP1M1 | 0.66287 | 4 | 0 | 4 |
| GADD45GIP1 | KLC2 | 0.650879 | 7 | 0 | 4 |
| GADD45GIP1 | SEMA3B | 0.6474 | 4 | 0 | 3 |
| GADD45GIP1 | THRB | 0.642145 | 3 | 0 | 3 |
| GADD45GIP1 | HES6 | 0.63334 | 3 | 0 | 3 |
| GADD45GIP1 | SLCO5A1 | 0.630348 | 3 | 0 | 3 |
| GADD45GIP1 | B9D1 | 0.622587 | 4 | 0 | 3 |
| GADD45GIP1 | TRAF3IP1 | 0.616823 | 4 | 0 | 4 |
| GADD45GIP1 | NAT14 | 0.615727 | 4 | 0 | 3 |
| GADD45GIP1 | GBX2 | 0.61233 | 4 | 0 | 3 |
| GADD45GIP1 | ASTN1 | 0.605738 | 3 | 0 | 3 |
| GADD45GIP1 | TMEM52 | 0.602746 | 3 | 0 | 3 |
| GADD45GIP1 | NDUFB2-AS1 | 0.591932 | 3 | 0 | 3 |
| GADD45GIP1 | ANKRD53 | 0.588146 | 4 | 0 | 3 |
| GADD45GIP1 | TMEM64 | 0.583222 | 3 | 0 | 3 |
| GADD45GIP1 | OBSL1 | 0.583197 | 5 | 0 | 4 |
| GADD45GIP1 | ALYREF | 0.57724 | 4 | 0 | 3 |
For details and further investigation, click here
