| Full name: Aly/REF export factor | Alias Symbol: ALY|BEF|ALY/REF|REF | ||
| Type: protein-coding gene | Cytoband: 17q25.3 | ||
| Entrez ID: 10189 | HGNC ID: HGNC:19071 | Ensembl Gene: ENSG00000183684 | OMIM ID: 604171 |
| Drug and gene relationship at DGIdb | |||
Expression of ALYREF:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ALYREF | 10189 | 226319_s_at | 0.5813 | 0.1922 | |
| GSE26886 | ALYREF | 10189 | 226320_at | -0.6179 | 0.0062 | |
| GSE45670 | ALYREF | 10189 | 226319_s_at | 0.3748 | 0.1135 | |
| GSE53622 | ALYREF | 10189 | 90383 | 0.2754 | 0.0000 | |
| GSE53624 | ALYREF | 10189 | 90383 | 0.6948 | 0.0000 | |
| GSE63941 | ALYREF | 10189 | 226319_s_at | 0.1048 | 0.8634 | |
| GSE77861 | ALYREF | 10189 | 226320_at | 0.5332 | 0.0872 | |
| SRP007169 | ALYREF | 10189 | RNAseq | 2.1782 | 0.0002 | |
| SRP008496 | ALYREF | 10189 | RNAseq | 1.4312 | 0.0012 | |
| SRP064894 | ALYREF | 10189 | RNAseq | 0.9201 | 0.0003 | |
| SRP133303 | ALYREF | 10189 | RNAseq | 0.6404 | 0.0014 | |
| SRP159526 | ALYREF | 10189 | RNAseq | 1.0732 | 0.0019 | |
| SRP193095 | ALYREF | 10189 | RNAseq | 0.3369 | 0.0096 | |
| SRP219564 | ALYREF | 10189 | RNAseq | 0.8234 | 0.1039 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by ALYREF expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of ALYREF:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ALYREF | 10189 | 4 | 4 | 22 | |
| GSE20123 | ALYREF | 10189 | 4 | 4 | 22 | |
| GSE43470 | ALYREF | 10189 | 3 | 5 | 35 | |
| GSE46452 | ALYREF | 10189 | 34 | 0 | 25 | |
| GSE47630 | ALYREF | 10189 | 9 | 2 | 29 | |
| GSE54993 | ALYREF | 10189 | 2 | 5 | 63 | |
| GSE54994 | ALYREF | 10189 | 10 | 6 | 37 | |
| GSE60625 | ALYREF | 10189 | 6 | 0 | 5 | |
| GSE74703 | ALYREF | 10189 | 3 | 3 | 30 | |
| GSE74704 | ALYREF | 10189 | 4 | 3 | 13 | |
| TCGA | ALYREF | 10189 | 25 | 12 | 59 |
Total number of gains: 104; Total number of losses: 44; Total Number of normals: 340.
Somatic mutations of ALYREF:
Generating mutation plots.
Highly correlated genes for ALYREF:
Showing top 20/354 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ALYREF | ZWILCH | 0.73802 | 4 | 0 | 4 |
| ALYREF | CCNB2 | 0.707211 | 3 | 0 | 3 |
| ALYREF | E2F7 | 0.704876 | 4 | 0 | 4 |
| ALYREF | BLM | 0.702051 | 4 | 0 | 4 |
| ALYREF | KIF11 | 0.698912 | 4 | 0 | 4 |
| ALYREF | CDK1 | 0.695611 | 4 | 0 | 4 |
| ALYREF | RCC1 | 0.693829 | 4 | 0 | 4 |
| ALYREF | HJURP | 0.689068 | 5 | 0 | 5 |
| ALYREF | BIRC5 | 0.689019 | 6 | 0 | 5 |
| ALYREF | KIF15 | 0.686929 | 4 | 0 | 4 |
| ALYREF | KIF23 | 0.686636 | 4 | 0 | 4 |
| ALYREF | CKAP2L | 0.684443 | 5 | 0 | 5 |
| ALYREF | MKI67 | 0.681563 | 4 | 0 | 4 |
| ALYREF | GINS2 | 0.67885 | 5 | 0 | 5 |
| ALYREF | KIF18B | 0.67682 | 3 | 0 | 3 |
| ALYREF | TTK | 0.674724 | 4 | 0 | 4 |
| ALYREF | RNASEH2A | 0.6744 | 5 | 0 | 5 |
| ALYREF | DDIAS | 0.6731 | 4 | 0 | 4 |
| ALYREF | PPIH | 0.667966 | 3 | 0 | 3 |
| ALYREF | ZWINT | 0.666588 | 4 | 0 | 4 |
For details and further investigation, click here
