| Full name: Wnt family member 7A | Alias Symbol: Wnt-7a | ||
| Type: protein-coding gene | Cytoband: 3p25.1 | ||
| Entrez ID: 7476 | HGNC ID: HGNC:12786 | Ensembl Gene: ENSG00000154764 | OMIM ID: 601570 |
| Drug and gene relationship at DGIdb | |||
WNT7A involved pathways:
Expression of WNT7A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | WNT7A | 7476 | 210248_at | 0.1633 | 0.7398 | |
| GSE20347 | WNT7A | 7476 | 210248_at | -0.0595 | 0.5466 | |
| GSE23400 | WNT7A | 7476 | 210248_at | 0.0308 | 0.5209 | |
| GSE26886 | WNT7A | 7476 | 210248_at | 0.1719 | 0.3384 | |
| GSE29001 | WNT7A | 7476 | 210248_at | -0.0290 | 0.9187 | |
| GSE38129 | WNT7A | 7476 | 210248_at | -0.0427 | 0.6816 | |
| GSE45670 | WNT7A | 7476 | 210248_at | 0.3294 | 0.0643 | |
| GSE53622 | WNT7A | 7476 | 87056 | 1.2004 | 0.0000 | |
| GSE53624 | WNT7A | 7476 | 87056 | 0.8420 | 0.0000 | |
| GSE63941 | WNT7A | 7476 | 210248_at | 0.4128 | 0.4365 | |
| GSE77861 | WNT7A | 7476 | 210248_at | -0.0892 | 0.3702 | |
| GSE97050 | WNT7A | 7476 | A_23_P258410 | 1.1554 | 0.1857 | |
| SRP007169 | WNT7A | 7476 | RNAseq | 1.1606 | 0.1571 | |
| SRP133303 | WNT7A | 7476 | RNAseq | 1.8347 | 0.0016 | |
| SRP219564 | WNT7A | 7476 | RNAseq | 0.8987 | 0.3389 | |
| TCGA | WNT7A | 7476 | RNAseq | 2.5724 | 0.0000 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by WNT7A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of WNT7A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | WNT7A | 7476 | 2 | 17 | 11 | |
| GSE20123 | WNT7A | 7476 | 2 | 17 | 11 | |
| GSE43470 | WNT7A | 7476 | 0 | 21 | 22 | |
| GSE46452 | WNT7A | 7476 | 2 | 17 | 40 | |
| GSE47630 | WNT7A | 7476 | 2 | 23 | 15 | |
| GSE54993 | WNT7A | 7476 | 6 | 1 | 63 | |
| GSE54994 | WNT7A | 7476 | 1 | 32 | 20 | |
| GSE60625 | WNT7A | 7476 | 5 | 0 | 6 | |
| GSE74703 | WNT7A | 7476 | 0 | 17 | 19 | |
| GSE74704 | WNT7A | 7476 | 1 | 10 | 9 | |
| TCGA | WNT7A | 7476 | 2 | 69 | 25 |
Total number of gains: 23; Total number of losses: 224; Total Number of normals: 241.
Somatic mutations of WNT7A:
Generating mutation plots.
Highly correlated genes for WNT7A:
Showing top 20/266 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| WNT7A | RAN | 0.714628 | 3 | 0 | 3 |
| WNT7A | MCTP1 | 0.69681 | 3 | 0 | 3 |
| WNT7A | SRM | 0.696793 | 3 | 0 | 3 |
| WNT7A | RNF181 | 0.690795 | 3 | 0 | 3 |
| WNT7A | CD79B | 0.675546 | 4 | 0 | 4 |
| WNT7A | C16orf74 | 0.662077 | 4 | 0 | 4 |
| WNT7A | STON2 | 0.65921 | 6 | 0 | 5 |
| WNT7A | C4orf36 | 0.653882 | 3 | 0 | 3 |
| WNT7A | NECAP2 | 0.65053 | 3 | 0 | 3 |
| WNT7A | ZNF324B | 0.649087 | 4 | 0 | 3 |
| WNT7A | GALR1 | 0.646714 | 3 | 0 | 3 |
| WNT7A | LIPG | 0.640648 | 4 | 0 | 4 |
| WNT7A | SARDH | 0.636725 | 4 | 0 | 3 |
| WNT7A | PLK2 | 0.634648 | 4 | 0 | 3 |
| WNT7A | RNF217 | 0.632936 | 3 | 0 | 3 |
| WNT7A | NUDT7 | 0.631082 | 3 | 0 | 3 |
| WNT7A | GPR132 | 0.629726 | 4 | 0 | 3 |
| WNT7A | AJUBA | 0.627265 | 5 | 0 | 3 |
| WNT7A | VPS33A | 0.626274 | 3 | 0 | 3 |
| WNT7A | NOL6 | 0.62465 | 4 | 0 | 3 |
For details and further investigation, click here
