GDPD2

 

Full name: glycerophosphodiester phosphodiesterase domain containing 2 Alias Symbol: OBDPF|FLJ20207|GDE3
Type: protein-coding gene Cytoband: Xq13.1
Entrez ID: 54857 HGNC ID: HGNC:25974 Ensembl Gene: ENSG00000130055 OMIM ID: 300940
Drug and gene relationship at DGIdb
Screen Evidence:
  • Knocking out of this gene by CRIPR/Cas9 screen found altered tolerance on DNA toxicity in Genotoxic Screens.

 

Expression of GDPD2:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 GDPD2 54857 220291_at 0.4177 0.3898
GSE20347 GDPD2 54857 220291_at 0.1176 0.3370
GSE23400 GDPD2 54857 220291_at -0.1471 0.0297
GSE26886 GDPD2 54857 220291_at -0.0560 0.7153
GSE29001 GDPD2 54857 220291_at 0.0277 0.9440
GSE38129 GDPD2 54857 220291_at 0.0666 0.6149
GSE45670 GDPD2 54857 220291_at 0.6865 0.0080
GSE53622 GDPD2 54857 102887 1.5406 0.0000
GSE53624 GDPD2 54857 102887 1.3453 0.0000
GSE63941 GDPD2 54857 220291_at 0.3423 0.1850
GSE77861 GDPD2 54857 220291_at 0.0611 0.7851
SRP133303 GDPD2 54857 RNAseq 1.2651 0.0001
TCGA GDPD2 54857 RNAseq 0.1388 0.8155

Upregulated datasets: 3; Downregulated datasets: 0.  


 

Survival by GDPD2 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of GDPD2:

 

No record found for this gene.


 

Somatic mutations of GDPD2:

 

Generating mutation plots.

 

Highly correlated genes for GDPD2:

 

Showing top 20/44 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
GDPD2DHRS20.673004303
GDPD2TBC1D10B0.67215303
GDPD2NPB0.622096303
GDPD2POU6F20.617945403
GDPD2C16orf740.614955303
GDPD2OPRM10.599373303
GDPD2CABLES20.597206303
GDPD2LINC011370.581532504
GDPD2WNT10A0.575561503
GDPD2SLC16A10.563564403
GDPD2PRKAR1B0.561974303
GDPD2ZNF5980.560809604
GDPD2SH2D50.558634403
GDPD2STRIP20.554641403
GDPD2MS4A50.549967603
GDPD2CYB5R10.548858503
GDPD2RPS6KA40.547116604
GDPD2B3GNT40.546323705
GDPD2PCSK70.545843303
GDPD2DNAH20.542273503

For details and further investigation, click here