| Full name: solute carrier family 16 member 1 | Alias Symbol: MCT|MCT1 | ||
| Type: protein-coding gene | Cytoband: 1p13.2 | ||
| Entrez ID: 6566 | HGNC ID: HGNC:10922 | Ensembl Gene: ENSG00000155380 | OMIM ID: 600682 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of SLC16A1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC16A1 | 6566 | 202236_s_at | 1.0834 | 0.1905 | |
| GSE20347 | SLC16A1 | 6566 | 202236_s_at | 1.5132 | 0.0000 | |
| GSE23400 | SLC16A1 | 6566 | 202236_s_at | 1.4152 | 0.0000 | |
| GSE26886 | SLC16A1 | 6566 | 202236_s_at | -0.1021 | 0.8459 | |
| GSE29001 | SLC16A1 | 6566 | 202234_s_at | 1.5570 | 0.0034 | |
| GSE38129 | SLC16A1 | 6566 | 202236_s_at | 1.6498 | 0.0000 | |
| GSE45670 | SLC16A1 | 6566 | 202236_s_at | 2.1387 | 0.0000 | |
| GSE53622 | SLC16A1 | 6566 | 87611 | 0.8823 | 0.0000 | |
| GSE53624 | SLC16A1 | 6566 | 87611 | 1.5265 | 0.0000 | |
| GSE63941 | SLC16A1 | 6566 | 202236_s_at | 1.6463 | 0.0506 | |
| GSE77861 | SLC16A1 | 6566 | 202236_s_at | 1.5303 | 0.0169 | |
| GSE97050 | SLC16A1 | 6566 | A_33_P3282434 | 0.4581 | 0.2248 | |
| SRP007169 | SLC16A1 | 6566 | RNAseq | 2.8023 | 0.0000 | |
| SRP008496 | SLC16A1 | 6566 | RNAseq | 2.3852 | 0.0000 | |
| SRP064894 | SLC16A1 | 6566 | RNAseq | 1.8568 | 0.0000 | |
| SRP133303 | SLC16A1 | 6566 | RNAseq | 2.4667 | 0.0000 | |
| SRP159526 | SLC16A1 | 6566 | RNAseq | 1.0271 | 0.0002 | |
| SRP193095 | SLC16A1 | 6566 | RNAseq | 0.9404 | 0.0018 | |
| SRP219564 | SLC16A1 | 6566 | RNAseq | 0.4518 | 0.4918 | |
| TCGA | SLC16A1 | 6566 | RNAseq | 0.2627 | 0.0005 |
Upregulated datasets: 12; Downregulated datasets: 0.
Survival by SLC16A1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC16A1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC16A1 | 6566 | 0 | 10 | 20 | |
| GSE20123 | SLC16A1 | 6566 | 0 | 10 | 20 | |
| GSE43470 | SLC16A1 | 6566 | 0 | 8 | 35 | |
| GSE46452 | SLC16A1 | 6566 | 2 | 1 | 56 | |
| GSE47630 | SLC16A1 | 6566 | 9 | 5 | 26 | |
| GSE54993 | SLC16A1 | 6566 | 0 | 1 | 69 | |
| GSE54994 | SLC16A1 | 6566 | 7 | 3 | 43 | |
| GSE60625 | SLC16A1 | 6566 | 0 | 0 | 11 | |
| GSE74703 | SLC16A1 | 6566 | 0 | 7 | 29 | |
| GSE74704 | SLC16A1 | 6566 | 0 | 6 | 14 | |
| TCGA | SLC16A1 | 6566 | 8 | 27 | 61 |
Total number of gains: 26; Total number of losses: 78; Total Number of normals: 384.
Somatic mutations of SLC16A1:
Generating mutation plots.
Highly correlated genes for SLC16A1:
Showing top 20/1334 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC16A1 | WDR54 | 0.748554 | 6 | 0 | 6 |
| SLC16A1 | SERPINH1 | 0.724037 | 8 | 0 | 8 |
| SLC16A1 | ITGA6 | 0.713934 | 11 | 0 | 11 |
| SLC16A1 | JOSD1 | 0.713422 | 9 | 0 | 8 |
| SLC16A1 | MTERF3 | 0.710949 | 6 | 0 | 6 |
| SLC16A1 | CEP78 | 0.708156 | 5 | 0 | 5 |
| SLC16A1 | GALNT18 | 0.706097 | 5 | 0 | 5 |
| SLC16A1 | FMNL2 | 0.704871 | 6 | 0 | 6 |
| SLC16A1 | CKS1B | 0.703022 | 11 | 0 | 11 |
| SLC16A1 | MSN | 0.700466 | 9 | 0 | 9 |
| SLC16A1 | LAMC2 | 0.698839 | 11 | 0 | 10 |
| SLC16A1 | SPDL1 | 0.698496 | 8 | 0 | 8 |
| SLC16A1 | COLGALT1 | 0.698303 | 8 | 0 | 7 |
| SLC16A1 | NTMT1 | 0.698191 | 5 | 0 | 5 |
| SLC16A1 | CBX3 | 0.696117 | 9 | 0 | 8 |
| SLC16A1 | LOXL2 | 0.692652 | 10 | 0 | 9 |
| SLC16A1 | SLC25A32 | 0.689235 | 10 | 0 | 10 |
| SLC16A1 | CDC6 | 0.688882 | 8 | 0 | 7 |
| SLC16A1 | CCT5 | 0.6879 | 8 | 0 | 7 |
| SLC16A1 | LRRC8D | 0.687128 | 11 | 0 | 11 |
For details and further investigation, click here
