| Full name: DDRGK domain containing 1 | Alias Symbol: dJ1187M17.3|UFBP1 | ||
| Type: protein-coding gene | Cytoband: 20p13 | ||
| Entrez ID: 65992 | HGNC ID: HGNC:16110 | Ensembl Gene: ENSG00000198171 | OMIM ID: 616177 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of DDRGK1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DDRGK1 | 65992 | 218159_at | 0.0802 | 0.8680 | |
| GSE20347 | DDRGK1 | 65992 | 218159_at | 0.0941 | 0.4580 | |
| GSE23400 | DDRGK1 | 65992 | 218159_at | 0.2453 | 0.0002 | |
| GSE26886 | DDRGK1 | 65992 | 218159_at | 0.4814 | 0.0300 | |
| GSE29001 | DDRGK1 | 65992 | 218159_at | 0.3699 | 0.0925 | |
| GSE38129 | DDRGK1 | 65992 | 218159_at | 0.2282 | 0.0965 | |
| GSE45670 | DDRGK1 | 65992 | 218159_at | 0.4672 | 0.0012 | |
| GSE53622 | DDRGK1 | 65992 | 29745 | 0.2120 | 0.0015 | |
| GSE53624 | DDRGK1 | 65992 | 29745 | 0.4761 | 0.0000 | |
| GSE63941 | DDRGK1 | 65992 | 218159_at | -0.4691 | 0.3048 | |
| GSE77861 | DDRGK1 | 65992 | 218159_at | 0.3092 | 0.1270 | |
| GSE97050 | DDRGK1 | 65992 | A_33_P3299781 | 0.4954 | 0.1272 | |
| SRP007169 | DDRGK1 | 65992 | RNAseq | -0.4830 | 0.3892 | |
| SRP008496 | DDRGK1 | 65992 | RNAseq | -0.0402 | 0.9186 | |
| SRP064894 | DDRGK1 | 65992 | RNAseq | 0.6861 | 0.0172 | |
| SRP133303 | DDRGK1 | 65992 | RNAseq | 0.0272 | 0.8361 | |
| SRP159526 | DDRGK1 | 65992 | RNAseq | 0.4670 | 0.0581 | |
| SRP193095 | DDRGK1 | 65992 | RNAseq | 0.0765 | 0.5460 | |
| SRP219564 | DDRGK1 | 65992 | RNAseq | 0.5376 | 0.1346 | |
| TCGA | DDRGK1 | 65992 | RNAseq | -0.0712 | 0.2108 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by DDRGK1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DDRGK1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DDRGK1 | 65992 | 12 | 3 | 15 | |
| GSE20123 | DDRGK1 | 65992 | 13 | 3 | 14 | |
| GSE43470 | DDRGK1 | 65992 | 10 | 1 | 32 | |
| GSE46452 | DDRGK1 | 65992 | 26 | 1 | 32 | |
| GSE47630 | DDRGK1 | 65992 | 18 | 4 | 18 | |
| GSE54993 | DDRGK1 | 65992 | 2 | 14 | 54 | |
| GSE54994 | DDRGK1 | 65992 | 24 | 2 | 27 | |
| GSE60625 | DDRGK1 | 65992 | 0 | 0 | 11 | |
| GSE74703 | DDRGK1 | 65992 | 9 | 1 | 26 | |
| GSE74704 | DDRGK1 | 65992 | 8 | 1 | 11 | |
| TCGA | DDRGK1 | 65992 | 40 | 11 | 45 |
Total number of gains: 162; Total number of losses: 41; Total Number of normals: 285.
Somatic mutations of DDRGK1:
Generating mutation plots.
Highly correlated genes for DDRGK1:
Showing top 20/248 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DDRGK1 | PPP1R9B | 0.741463 | 3 | 0 | 3 |
| DDRGK1 | CREB3L1 | 0.686517 | 3 | 0 | 3 |
| DDRGK1 | FAM160A2 | 0.671148 | 3 | 0 | 3 |
| DDRGK1 | TMEM214 | 0.664175 | 3 | 0 | 3 |
| DDRGK1 | UTP15 | 0.661366 | 3 | 0 | 3 |
| DDRGK1 | PATL1 | 0.646741 | 3 | 0 | 3 |
| DDRGK1 | ADCY3 | 0.644244 | 3 | 0 | 3 |
| DDRGK1 | TNFRSF21 | 0.639593 | 4 | 0 | 3 |
| DDRGK1 | ABCD4 | 0.635154 | 3 | 0 | 3 |
| DDRGK1 | TMEM132A | 0.63309 | 4 | 0 | 3 |
| DDRGK1 | STEAP1B | 0.626311 | 4 | 0 | 3 |
| DDRGK1 | CXCL16 | 0.625427 | 3 | 0 | 3 |
| DDRGK1 | ITPA | 0.622475 | 12 | 0 | 8 |
| DDRGK1 | SLC25A15 | 0.620154 | 3 | 0 | 3 |
| DDRGK1 | GFER | 0.615257 | 3 | 0 | 3 |
| DDRGK1 | AAK1 | 0.613013 | 4 | 0 | 3 |
| DDRGK1 | SMIM3 | 0.61183 | 3 | 0 | 3 |
| DDRGK1 | CDHR1 | 0.610109 | 3 | 0 | 3 |
| DDRGK1 | DYRK3 | 0.609558 | 3 | 0 | 3 |
| DDRGK1 | NOP56 | 0.607529 | 3 | 0 | 3 |
For details and further investigation, click here
