| Full name: dynein axonemal assembly factor 3 | Alias Symbol: FLJ40069|FLJ36139|PF22|PCD | ||
| Type: protein-coding gene | Cytoband: 19q13.42 | ||
| Entrez ID: 352909 | HGNC ID: HGNC:30492 | Ensembl Gene: ENSG00000167646 | OMIM ID: 614566 |
| Drug and gene relationship at DGIdb | |||
Expression of DNAAF3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DNAAF3 | 352909 | 230033_at | 0.6515 | 0.2347 | |
| GSE26886 | DNAAF3 | 352909 | 230033_at | 0.4154 | 0.0237 | |
| GSE45670 | DNAAF3 | 352909 | 230033_at | 0.2982 | 0.0146 | |
| GSE53622 | DNAAF3 | 352909 | 40655 | 0.5148 | 0.0725 | |
| GSE53624 | DNAAF3 | 352909 | 40655 | 0.6719 | 0.0008 | |
| GSE63941 | DNAAF3 | 352909 | 230033_at | 0.7552 | 0.0546 | |
| GSE77861 | DNAAF3 | 352909 | 230033_at | -0.0745 | 0.5951 | |
| SRP133303 | DNAAF3 | 352909 | RNAseq | 0.4744 | 0.2166 | |
| SRP159526 | DNAAF3 | 352909 | RNAseq | 0.1272 | 0.8590 | |
| SRP219564 | DNAAF3 | 352909 | RNAseq | -0.3439 | 0.6623 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by DNAAF3 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of DNAAF3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DNAAF3 | 352909 | 3 | 4 | 23 | |
| GSE20123 | DNAAF3 | 352909 | 3 | 3 | 24 | |
| GSE43470 | DNAAF3 | 352909 | 3 | 11 | 29 | |
| GSE46452 | DNAAF3 | 352909 | 45 | 1 | 13 | |
| GSE47630 | DNAAF3 | 352909 | 8 | 6 | 26 | |
| GSE54993 | DNAAF3 | 352909 | 17 | 4 | 49 | |
| GSE54994 | DNAAF3 | 352909 | 4 | 13 | 36 | |
| GSE60625 | DNAAF3 | 352909 | 9 | 0 | 2 | |
| GSE74703 | DNAAF3 | 352909 | 3 | 7 | 26 | |
| GSE74704 | DNAAF3 | 352909 | 3 | 1 | 16 | |
| TCGA | DNAAF3 | 352909 | 19 | 14 | 63 |
Total number of gains: 117; Total number of losses: 64; Total Number of normals: 307.
Somatic mutations of DNAAF3:
Generating mutation plots.
Highly correlated genes for DNAAF3:
Showing top 20/83 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DNAAF3 | DLX3 | 0.68977 | 3 | 0 | 3 |
| DNAAF3 | TNNT1 | 0.677917 | 6 | 0 | 6 |
| DNAAF3 | PCBP4 | 0.670017 | 3 | 0 | 3 |
| DNAAF3 | SLC2A4RG | 0.657005 | 4 | 0 | 3 |
| DNAAF3 | PXMP2 | 0.629125 | 3 | 0 | 3 |
| DNAAF3 | CHPF | 0.622342 | 3 | 0 | 3 |
| DNAAF3 | GFER | 0.622051 | 3 | 0 | 3 |
| DNAAF3 | RAC3 | 0.614571 | 3 | 0 | 3 |
| DNAAF3 | MLXIPL | 0.613848 | 3 | 0 | 3 |
| DNAAF3 | POLD1 | 0.611634 | 3 | 0 | 3 |
| DNAAF3 | CNTROB | 0.610083 | 4 | 0 | 3 |
| DNAAF3 | MFSD10 | 0.603478 | 4 | 0 | 4 |
| DNAAF3 | KREMEN2 | 0.602393 | 5 | 0 | 4 |
| DNAAF3 | ADAMTSL2 | 0.600259 | 3 | 0 | 3 |
| DNAAF3 | NPEPL1 | 0.599092 | 3 | 0 | 3 |
| DNAAF3 | RGS20 | 0.596545 | 5 | 0 | 4 |
| DNAAF3 | POU5F1B | 0.59252 | 4 | 0 | 3 |
| DNAAF3 | TREM2 | 0.591081 | 4 | 0 | 3 |
| DNAAF3 | PLEK2 | 0.589518 | 5 | 0 | 3 |
| DNAAF3 | FSCN1 | 0.588182 | 5 | 0 | 3 |
For details and further investigation, click here
