FSCN1

 

Full name: fascin actin-bundling protein 1 Alias Symbol: p55|FLJ38511
Type: protein-coding gene Cytoband: 7p22.1
Entrez ID: 6624 HGNC ID: HGNC:11148 Ensembl Gene: ENSG00000075618 OMIM ID: 602689
Drug and gene relationship at DGIdb

 

Expression of FSCN1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 FSCN1 6624 201564_s_at 1.4322 0.2895
GSE20347 FSCN1 6624 201564_s_at 1.6976 0.0000
GSE23400 FSCN1 6624 201564_s_at 1.7832 0.0000
GSE26886 FSCN1 6624 201564_s_at 1.6008 0.0000
GSE29001 FSCN1 6624 201564_s_at 1.5917 0.0012
GSE38129 FSCN1 6624 201564_s_at 2.1684 0.0000
GSE45670 FSCN1 6624 201564_s_at 2.0147 0.0000
GSE53622 FSCN1 6624 16861 2.2347 0.0000
GSE53624 FSCN1 6624 16861 2.4479 0.0000
GSE63941 FSCN1 6624 210933_s_at 2.1244 0.0090
GSE77861 FSCN1 6624 201564_s_at 1.9361 0.0004
GSE97050 FSCN1 6624 A_33_P3411075 2.9071 0.0454
SRP007169 FSCN1 6624 RNAseq 2.6997 0.0000
SRP008496 FSCN1 6624 RNAseq 2.5515 0.0000
SRP064894 FSCN1 6624 RNAseq 2.4032 0.0000
SRP133303 FSCN1 6624 RNAseq 2.7783 0.0000
SRP159526 FSCN1 6624 RNAseq 2.2695 0.0000
SRP193095 FSCN1 6624 RNAseq 2.6415 0.0000
SRP219564 FSCN1 6624 RNAseq 1.8346 0.0104
TCGA FSCN1 6624 RNAseq 0.9519 0.0000

Upregulated datasets: 18; Downregulated datasets: 0.  

 

Survival by FSCN1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of FSCN1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 FSCN1 6624 14 1 15
GSE20123 FSCN1 6624 14 1 15
GSE43470 FSCN1 6624 6 1 36
GSE46452 FSCN1 6624 13 1 45
GSE47630 FSCN1 6624 9 1 30
GSE54993 FSCN1 6624 0 6 64
GSE54994 FSCN1 6624 22 1 30
GSE60625 FSCN1 6624 0 0 11
GSE74703 FSCN1 6624 6 0 30
GSE74704 FSCN1 6624 9 0 11
TCGA FSCN1 6624 55 5 36

Total number of gains: 148; Total number of losses: 17; Total Number of normals: 323.  

 

Somatic mutations of FSCN1:

 

Generating mutation plots.

 

Highly correlated genes for FSCN1:

 

Showing top 20/1952 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
FSCN1TENM20.812221606
FSCN1LEPR0.808443303
FSCN1MFAP20.78518211010
FSCN1MMP10.77970612011
FSCN1FMNL20.77672707
FSCN1TPX20.77640612012
FSCN1WDR660.776055808
FSCN1UBE2C0.77455212011
FSCN1MYBL20.77273912011
FSCN1PTK70.771411010
FSCN1USB10.76909110010
FSCN1AURKB0.76877112012
FSCN1PLAU0.76587412011
FSCN1LAMC20.7625213011
FSCN1RNASEH2A0.75820211011
FSCN1CKS1B0.75813312012
FSCN1ADAMTS140.758087404
FSCN1DNMT10.75765811011
FSCN1CDH30.75745911011
FSCN1SNAI20.756982908

For details and further investigation, click here