| Full name: DnaJ heat shock protein family (Hsp40) member C5 | Alias Symbol: FLJ00118|FLJ13070|DNAJC5A | ||
| Type: protein-coding gene | Cytoband: 20q13.33 | ||
| Entrez ID: 80331 | HGNC ID: HGNC:16235 | Ensembl Gene: ENSG00000101152 | OMIM ID: 611203 |
| Drug and gene relationship at DGIdb | |||
Expression of DNAJC5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DNAJC5 | 80331 | 224612_s_at | 0.5353 | 0.4429 | |
| GSE26886 | DNAJC5 | 80331 | 224611_s_at | -1.7142 | 0.0000 | |
| GSE45670 | DNAJC5 | 80331 | 224611_s_at | 0.0572 | 0.7642 | |
| GSE53622 | DNAJC5 | 80331 | 13962 | -0.1875 | 0.0015 | |
| GSE53624 | DNAJC5 | 80331 | 13962 | -0.3645 | 0.0000 | |
| GSE63941 | DNAJC5 | 80331 | 224611_s_at | -0.3831 | 0.3837 | |
| GSE77861 | DNAJC5 | 80331 | 224612_s_at | -0.7803 | 0.0025 | |
| GSE97050 | DNAJC5 | 80331 | A_33_P3419733 | -0.0355 | 0.8820 | |
| SRP007169 | DNAJC5 | 80331 | RNAseq | -2.3680 | 0.0000 | |
| SRP008496 | DNAJC5 | 80331 | RNAseq | -2.1722 | 0.0000 | |
| SRP064894 | DNAJC5 | 80331 | RNAseq | -0.9088 | 0.0000 | |
| SRP133303 | DNAJC5 | 80331 | RNAseq | -0.7220 | 0.0000 | |
| SRP159526 | DNAJC5 | 80331 | RNAseq | -1.0472 | 0.0000 | |
| SRP193095 | DNAJC5 | 80331 | RNAseq | -0.8327 | 0.0000 | |
| SRP219564 | DNAJC5 | 80331 | RNAseq | -1.1359 | 0.0048 | |
| TCGA | DNAJC5 | 80331 | RNAseq | -0.0650 | 0.1643 |
Upregulated datasets: 0; Downregulated datasets: 5.
Survival by DNAJC5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DNAJC5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DNAJC5 | 80331 | 13 | 2 | 15 | |
| GSE20123 | DNAJC5 | 80331 | 13 | 2 | 15 | |
| GSE43470 | DNAJC5 | 80331 | 11 | 1 | 31 | |
| GSE46452 | DNAJC5 | 80331 | 35 | 0 | 24 | |
| GSE47630 | DNAJC5 | 80331 | 25 | 1 | 14 | |
| GSE54993 | DNAJC5 | 80331 | 0 | 17 | 53 | |
| GSE54994 | DNAJC5 | 80331 | 29 | 0 | 24 | |
| GSE60625 | DNAJC5 | 80331 | 0 | 0 | 11 | |
| GSE74703 | DNAJC5 | 80331 | 10 | 0 | 26 | |
| GSE74704 | DNAJC5 | 80331 | 10 | 0 | 10 | |
| TCGA | DNAJC5 | 80331 | 44 | 4 | 48 |
Total number of gains: 190; Total number of losses: 27; Total Number of normals: 271.
Somatic mutations of DNAJC5:
Generating mutation plots.
Highly correlated genes for DNAJC5:
Showing top 20/401 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DNAJC5 | GID8 | 0.774974 | 5 | 0 | 5 |
| DNAJC5 | TMPRSS2 | 0.771862 | 3 | 0 | 3 |
| DNAJC5 | USP46 | 0.756832 | 3 | 0 | 3 |
| DNAJC5 | TM9SF4 | 0.746973 | 4 | 0 | 4 |
| DNAJC5 | TBC1D20 | 0.729924 | 4 | 0 | 4 |
| DNAJC5 | DHCR24 | 0.713887 | 5 | 0 | 5 |
| DNAJC5 | ACPP | 0.704196 | 4 | 0 | 3 |
| DNAJC5 | HSD17B10 | 0.701323 | 3 | 0 | 3 |
| DNAJC5 | PRDX1 | 0.698631 | 3 | 0 | 3 |
| DNAJC5 | PRADC1 | 0.693007 | 3 | 0 | 3 |
| DNAJC5 | SERPINB3 | 0.689627 | 3 | 0 | 3 |
| DNAJC5 | IL10RB | 0.687194 | 3 | 0 | 3 |
| DNAJC5 | ELMO2 | 0.686534 | 6 | 0 | 5 |
| DNAJC5 | PANK2 | 0.684076 | 6 | 0 | 6 |
| DNAJC5 | CMPK1 | 0.683982 | 3 | 0 | 3 |
| DNAJC5 | APEH | 0.678152 | 4 | 0 | 3 |
| DNAJC5 | RDH12 | 0.672903 | 4 | 0 | 3 |
| DNAJC5 | CXCL17 | 0.672765 | 4 | 0 | 3 |
| DNAJC5 | SPNS2 | 0.666772 | 4 | 0 | 3 |
| DNAJC5 | MOSPD1 | 0.665944 | 4 | 0 | 3 |
For details and further investigation, click here
