| Full name: PPARGC1 and ESRR induced regulator, muscle 1 | Alias Symbol: MGC13275|RP11-54O7.8|Perm1 | ||
| Type: protein-coding gene | Cytoband: 1p36.33 | ||
| Entrez ID: 84808 | HGNC ID: HGNC:28208 | Ensembl Gene: ENSG00000187642 | OMIM ID: 615921 |
| Drug and gene relationship at DGIdb | |||
Expression of PERM1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PERM1 | 84808 | 224501_at | 0.0014 | 0.9966 | |
| GSE26886 | PERM1 | 84808 | 224501_at | 0.2538 | 0.0622 | |
| GSE45670 | PERM1 | 84808 | 224501_at | -0.1180 | 0.2074 | |
| GSE53622 | PERM1 | 84808 | 39964 | -0.4670 | 0.0000 | |
| GSE53624 | PERM1 | 84808 | 39964 | -0.3764 | 0.0000 | |
| GSE63941 | PERM1 | 84808 | 224501_at | 0.2034 | 0.1403 | |
| GSE77861 | PERM1 | 84808 | 224501_at | -0.1598 | 0.3601 | |
| SRP133303 | PERM1 | 84808 | RNAseq | -1.8067 | 0.0000 | |
| SRP159526 | PERM1 | 84808 | RNAseq | -1.3820 | 0.0449 | |
| SRP219564 | PERM1 | 84808 | RNAseq | -0.8492 | 0.3734 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by PERM1 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of PERM1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PERM1 | 84808 | 3 | 7 | 20 | |
| GSE20123 | PERM1 | 84808 | 3 | 6 | 21 | |
| GSE43470 | PERM1 | 84808 | 1 | 5 | 37 | |
| GSE46452 | PERM1 | 84808 | 7 | 1 | 51 | |
| GSE47630 | PERM1 | 84808 | 8 | 4 | 28 | |
| GSE54993 | PERM1 | 84808 | 2 | 2 | 66 | |
| GSE54994 | PERM1 | 84808 | 15 | 2 | 36 | |
| GSE60625 | PERM1 | 84808 | 0 | 0 | 11 | |
| GSE74703 | PERM1 | 84808 | 1 | 3 | 32 | |
| GSE74704 | PERM1 | 84808 | 3 | 0 | 17 |
Total number of gains: 43; Total number of losses: 30; Total Number of normals: 319.
Somatic mutations of PERM1:
Generating mutation plots.
Highly correlated genes for PERM1:
Showing top 20/237 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PERM1 | GJC2 | 0.766576 | 3 | 0 | 3 |
| PERM1 | MLXIPL | 0.718827 | 4 | 0 | 4 |
| PERM1 | NKAIN4 | 0.701171 | 3 | 0 | 3 |
| PERM1 | IL34 | 0.694212 | 4 | 0 | 4 |
| PERM1 | SARDH | 0.689778 | 3 | 0 | 3 |
| PERM1 | LHX1 | 0.689174 | 4 | 0 | 4 |
| PERM1 | DCD | 0.687287 | 3 | 0 | 3 |
| PERM1 | NOXA1 | 0.680905 | 5 | 0 | 5 |
| PERM1 | TSC22D4 | 0.674911 | 5 | 0 | 5 |
| PERM1 | APOC2 | 0.667525 | 3 | 0 | 3 |
| PERM1 | JSRP1 | 0.665881 | 3 | 0 | 3 |
| PERM1 | PAX4 | 0.664708 | 3 | 0 | 3 |
| PERM1 | CASR | 0.662414 | 3 | 0 | 3 |
| PERM1 | ARL4D | 0.657581 | 3 | 0 | 3 |
| PERM1 | ESPNL | 0.656604 | 3 | 0 | 3 |
| PERM1 | ARHGAP30 | 0.655957 | 3 | 0 | 3 |
| PERM1 | FBLL1 | 0.654799 | 4 | 0 | 4 |
| PERM1 | UNK | 0.652025 | 3 | 0 | 3 |
| PERM1 | MAG | 0.649873 | 3 | 0 | 3 |
| PERM1 | C20orf141 | 0.642773 | 4 | 0 | 4 |
For details and further investigation, click here
