| Full name: acyl-CoA thioesterase 11 | Alias Symbol: STARD14|BFIT|KIAA0707|BFIT1|THEM1 | ||
| Type: protein-coding gene | Cytoband: 1p32.3 | ||
| Entrez ID: 26027 | HGNC ID: HGNC:18156 | Ensembl Gene: ENSG00000162390 | OMIM ID: 606803 |
| Drug and gene relationship at DGIdb | |||
Expression of ACOT11:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ACOT11 | 26027 | 214763_at | -0.3495 | 0.7162 | |
| GSE20347 | ACOT11 | 26027 | 214763_at | -0.6586 | 0.0000 | |
| GSE23400 | ACOT11 | 26027 | 214763_at | -0.6052 | 0.0000 | |
| GSE26886 | ACOT11 | 26027 | 214763_at | -1.2274 | 0.0000 | |
| GSE29001 | ACOT11 | 26027 | 214763_at | -0.8865 | 0.0103 | |
| GSE38129 | ACOT11 | 26027 | 214763_at | -0.6142 | 0.0006 | |
| GSE45670 | ACOT11 | 26027 | 214763_at | -0.2935 | 0.2936 | |
| GSE53622 | ACOT11 | 26027 | 38237 | -1.0479 | 0.0000 | |
| GSE53624 | ACOT11 | 26027 | 38237 | -1.2311 | 0.0000 | |
| GSE63941 | ACOT11 | 26027 | 214763_at | 0.6731 | 0.1005 | |
| GSE77861 | ACOT11 | 26027 | 214763_at | -0.5160 | 0.0069 | |
| GSE97050 | ACOT11 | 26027 | A_23_P417415 | -0.3034 | 0.4306 | |
| SRP007169 | ACOT11 | 26027 | RNAseq | -1.9557 | 0.0006 | |
| SRP008496 | ACOT11 | 26027 | RNAseq | -2.0460 | 0.0000 | |
| SRP064894 | ACOT11 | 26027 | RNAseq | -0.9508 | 0.0000 | |
| SRP133303 | ACOT11 | 26027 | RNAseq | -0.5382 | 0.0000 | |
| SRP159526 | ACOT11 | 26027 | RNAseq | -1.4698 | 0.0000 | |
| SRP193095 | ACOT11 | 26027 | RNAseq | -0.5795 | 0.0011 | |
| SRP219564 | ACOT11 | 26027 | RNAseq | 0.5672 | 0.2836 | |
| TCGA | ACOT11 | 26027 | RNAseq | -0.3295 | 0.0037 |
Upregulated datasets: 0; Downregulated datasets: 6.
Survival by ACOT11 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ACOT11:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ACOT11 | 26027 | 3 | 5 | 22 | |
| GSE20123 | ACOT11 | 26027 | 3 | 4 | 23 | |
| GSE43470 | ACOT11 | 26027 | 7 | 2 | 34 | |
| GSE46452 | ACOT11 | 26027 | 2 | 1 | 56 | |
| GSE47630 | ACOT11 | 26027 | 8 | 4 | 28 | |
| GSE54993 | ACOT11 | 26027 | 0 | 0 | 70 | |
| GSE54994 | ACOT11 | 26027 | 10 | 2 | 41 | |
| GSE60625 | ACOT11 | 26027 | 0 | 0 | 11 | |
| GSE74703 | ACOT11 | 26027 | 5 | 1 | 30 | |
| GSE74704 | ACOT11 | 26027 | 2 | 0 | 18 | |
| TCGA | ACOT11 | 26027 | 10 | 18 | 68 |
Total number of gains: 50; Total number of losses: 37; Total Number of normals: 401.
Somatic mutations of ACOT11:
Generating mutation plots.
Highly correlated genes for ACOT11:
Showing top 20/1402 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ACOT11 | MAPK3 | 0.751154 | 12 | 0 | 11 |
| ACOT11 | EPGN | 0.750887 | 3 | 0 | 3 |
| ACOT11 | EPS8L2 | 0.749465 | 10 | 0 | 10 |
| ACOT11 | CYSRT1 | 0.746166 | 6 | 0 | 6 |
| ACOT11 | GDPD3 | 0.744274 | 12 | 0 | 12 |
| ACOT11 | SLC35C1 | 0.743701 | 10 | 0 | 9 |
| ACOT11 | UPK3B | 0.737133 | 3 | 0 | 3 |
| ACOT11 | TRIP10 | 0.73568 | 11 | 0 | 11 |
| ACOT11 | SLC13A4 | 0.735576 | 10 | 0 | 10 |
| ACOT11 | ASPG | 0.734259 | 5 | 0 | 5 |
| ACOT11 | KRT78 | 0.727273 | 7 | 0 | 7 |
| ACOT11 | KLK13 | 0.72601 | 10 | 0 | 10 |
| ACOT11 | TMEM40 | 0.725589 | 11 | 0 | 11 |
| ACOT11 | SH3BGRL2 | 0.723254 | 6 | 0 | 6 |
| ACOT11 | CWH43 | 0.720192 | 10 | 0 | 10 |
| ACOT11 | C1orf116 | 0.720185 | 12 | 0 | 11 |
| ACOT11 | TMEM154 | 0.719655 | 7 | 0 | 6 |
| ACOT11 | PTK6 | 0.718466 | 12 | 0 | 10 |
| ACOT11 | SCNN1B | 0.718239 | 11 | 0 | 10 |
| ACOT11 | MXD1 | 0.717404 | 11 | 0 | 10 |
For details and further investigation, click here
