| Full name: tubulin tyrosine ligase like 11 | Alias Symbol: bA244O19.1 | ||
| Type: protein-coding gene | Cytoband: 9q33.2 | ||
| Entrez ID: 158135 | HGNC ID: HGNC:18113 | Ensembl Gene: ENSG00000175764 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of TTLL11:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TTLL11 | 158135 | 228172_at | 0.0440 | 0.9448 | |
| GSE26886 | TTLL11 | 158135 | 228172_at | 0.3501 | 0.0423 | |
| GSE45670 | TTLL11 | 158135 | 228172_at | -0.0394 | 0.8953 | |
| GSE53622 | TTLL11 | 158135 | 82763 | -1.0788 | 0.0000 | |
| GSE53624 | TTLL11 | 158135 | 82763 | -0.7867 | 0.0000 | |
| GSE63941 | TTLL11 | 158135 | 228172_at | -0.5964 | 0.0446 | |
| GSE77861 | TTLL11 | 158135 | 228172_at | -0.0730 | 0.6098 | |
| GSE97050 | TTLL11 | 158135 | A_23_P333852 | -1.2147 | 0.0835 | |
| SRP064894 | TTLL11 | 158135 | RNAseq | -0.1687 | 0.4914 | |
| SRP133303 | TTLL11 | 158135 | RNAseq | -0.2788 | 0.3944 | |
| SRP159526 | TTLL11 | 158135 | RNAseq | -0.5036 | 0.2369 | |
| SRP193095 | TTLL11 | 158135 | RNAseq | -0.4394 | 0.0011 | |
| SRP219564 | TTLL11 | 158135 | RNAseq | 0.0308 | 0.9538 | |
| TCGA | TTLL11 | 158135 | RNAseq | -0.3378 | 0.0026 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by TTLL11 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TTLL11:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TTLL11 | 158135 | 3 | 7 | 20 | |
| GSE20123 | TTLL11 | 158135 | 3 | 7 | 20 | |
| GSE43470 | TTLL11 | 158135 | 5 | 4 | 34 | |
| GSE46452 | TTLL11 | 158135 | 6 | 13 | 40 | |
| GSE47630 | TTLL11 | 158135 | 3 | 16 | 21 | |
| GSE54993 | TTLL11 | 158135 | 3 | 3 | 64 | |
| GSE54994 | TTLL11 | 158135 | 9 | 10 | 34 | |
| GSE60625 | TTLL11 | 158135 | 0 | 0 | 11 | |
| GSE74703 | TTLL11 | 158135 | 5 | 3 | 28 | |
| GSE74704 | TTLL11 | 158135 | 2 | 5 | 13 | |
| TCGA | TTLL11 | 158135 | 27 | 24 | 45 |
Total number of gains: 66; Total number of losses: 92; Total Number of normals: 330.
Somatic mutations of TTLL11:
Generating mutation plots.
Highly correlated genes for TTLL11:
Showing top 20/341 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TTLL11 | HSPB6 | 0.795977 | 3 | 0 | 3 |
| TTLL11 | NKX6-1 | 0.781536 | 3 | 0 | 3 |
| TTLL11 | ATP1A2 | 0.773964 | 3 | 0 | 3 |
| TTLL11 | RBPMS2 | 0.76627 | 3 | 0 | 3 |
| TTLL11 | THRB | 0.76086 | 3 | 0 | 3 |
| TTLL11 | BCHE | 0.760089 | 3 | 0 | 3 |
| TTLL11 | PLXNB3 | 0.759119 | 3 | 0 | 3 |
| TTLL11 | RAP1A | 0.758473 | 3 | 0 | 3 |
| TTLL11 | PCP4 | 0.753821 | 3 | 0 | 3 |
| TTLL11 | XKR4 | 0.751903 | 3 | 0 | 3 |
| TTLL11 | PCSK2 | 0.751137 | 3 | 0 | 3 |
| TTLL11 | KCNMA1 | 0.749631 | 3 | 0 | 3 |
| TTLL11 | ITPR1 | 0.746671 | 3 | 0 | 3 |
| TTLL11 | RAB3GAP1 | 0.746637 | 3 | 0 | 3 |
| TTLL11 | ITGA9 | 0.73955 | 3 | 0 | 3 |
| TTLL11 | OGN | 0.735719 | 3 | 0 | 3 |
| TTLL11 | CLEC3B | 0.733359 | 3 | 0 | 3 |
| TTLL11 | FRMD3 | 0.733097 | 3 | 0 | 3 |
| TTLL11 | SORCS1 | 0.726833 | 3 | 0 | 3 |
| TTLL11 | RIC3 | 0.725619 | 3 | 0 | 3 |
For details and further investigation, click here
