| Full name: SLAM family member 8 | Alias Symbol: BLAME|SBBI42|CD353 | ||
| Type: protein-coding gene | Cytoband: 1q23.2 | ||
| Entrez ID: 56833 | HGNC ID: HGNC:21391 | Ensembl Gene: ENSG00000158714 | OMIM ID: 606620 |
| Drug and gene relationship at DGIdb | |||
Expression of SLAMF8:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLAMF8 | 56833 | 219386_s_at | 0.9437 | 0.4454 | |
| GSE20347 | SLAMF8 | 56833 | 219385_at | 0.3296 | 0.0363 | |
| GSE23400 | SLAMF8 | 56833 | 219385_at | 0.1836 | 0.0001 | |
| GSE26886 | SLAMF8 | 56833 | 219385_at | 0.0244 | 0.9379 | |
| GSE29001 | SLAMF8 | 56833 | 219385_at | 0.2442 | 0.2313 | |
| GSE38129 | SLAMF8 | 56833 | 219386_s_at | 0.7913 | 0.0047 | |
| GSE45670 | SLAMF8 | 56833 | 219386_s_at | 0.5514 | 0.0742 | |
| GSE53622 | SLAMF8 | 56833 | 61592 | 1.2094 | 0.0000 | |
| GSE53624 | SLAMF8 | 56833 | 61592 | 1.2086 | 0.0000 | |
| GSE63941 | SLAMF8 | 56833 | 219385_at | -0.0763 | 0.6684 | |
| GSE77861 | SLAMF8 | 56833 | 219385_at | 0.0270 | 0.8466 | |
| GSE97050 | SLAMF8 | 56833 | A_23_P200138 | 1.1496 | 0.1782 | |
| SRP007169 | SLAMF8 | 56833 | RNAseq | 3.0903 | 0.0004 | |
| SRP008496 | SLAMF8 | 56833 | RNAseq | 2.3401 | 0.0002 | |
| SRP064894 | SLAMF8 | 56833 | RNAseq | 1.7002 | 0.0000 | |
| SRP133303 | SLAMF8 | 56833 | RNAseq | 1.4399 | 0.0000 | |
| SRP159526 | SLAMF8 | 56833 | RNAseq | 0.4993 | 0.4732 | |
| SRP193095 | SLAMF8 | 56833 | RNAseq | 1.0031 | 0.0000 | |
| SRP219564 | SLAMF8 | 56833 | RNAseq | 1.5470 | 0.0008 | |
| TCGA | SLAMF8 | 56833 | RNAseq | 0.6054 | 0.0000 |
Upregulated datasets: 8; Downregulated datasets: 0.
Survival by SLAMF8 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLAMF8:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLAMF8 | 56833 | 10 | 0 | 20 | |
| GSE20123 | SLAMF8 | 56833 | 10 | 0 | 20 | |
| GSE43470 | SLAMF8 | 56833 | 7 | 2 | 34 | |
| GSE46452 | SLAMF8 | 56833 | 2 | 1 | 56 | |
| GSE47630 | SLAMF8 | 56833 | 14 | 0 | 26 | |
| GSE54993 | SLAMF8 | 56833 | 0 | 5 | 65 | |
| GSE54994 | SLAMF8 | 56833 | 16 | 0 | 37 | |
| GSE60625 | SLAMF8 | 56833 | 0 | 0 | 11 | |
| GSE74703 | SLAMF8 | 56833 | 7 | 2 | 27 | |
| GSE74704 | SLAMF8 | 56833 | 4 | 0 | 16 | |
| TCGA | SLAMF8 | 56833 | 43 | 3 | 50 |
Total number of gains: 113; Total number of losses: 13; Total Number of normals: 362.
Somatic mutations of SLAMF8:
Generating mutation plots.
Highly correlated genes for SLAMF8:
Showing top 20/545 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLAMF8 | TFEC | 0.799865 | 10 | 0 | 10 |
| SLAMF8 | HAVCR2 | 0.766084 | 5 | 0 | 5 |
| SLAMF8 | SLC7A7 | 0.760203 | 11 | 0 | 11 |
| SLAMF8 | LCP2 | 0.735344 | 9 | 0 | 9 |
| SLAMF8 | LAPTM5 | 0.723297 | 10 | 0 | 10 |
| SLAMF8 | SIGLEC12 | 0.720016 | 3 | 0 | 3 |
| SLAMF8 | ADAMDEC1 | 0.714266 | 10 | 0 | 9 |
| SLAMF8 | TYROBP | 0.713091 | 12 | 0 | 11 |
| SLAMF8 | FPR3 | 0.709272 | 9 | 0 | 7 |
| SLAMF8 | CYBB | 0.700454 | 11 | 0 | 9 |
| SLAMF8 | CPXM1 | 0.699723 | 4 | 0 | 4 |
| SLAMF8 | GJD3 | 0.698019 | 4 | 0 | 3 |
| SLAMF8 | FCGR1B | 0.686777 | 10 | 0 | 9 |
| SLAMF8 | AIF1 | 0.683119 | 11 | 0 | 10 |
| SLAMF8 | CD53 | 0.681282 | 9 | 0 | 9 |
| SLAMF8 | FAM78A | 0.680858 | 4 | 0 | 4 |
| SLAMF8 | CD86 | 0.677887 | 8 | 0 | 7 |
| SLAMF8 | CD300A | 0.676086 | 11 | 0 | 10 |
| SLAMF8 | GLB1 | 0.67469 | 3 | 0 | 3 |
| SLAMF8 | GZMB | 0.672639 | 11 | 0 | 9 |
For details and further investigation, click here
