| Full name: glycine receptor alpha 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 5q33.1 | ||
| Entrez ID: 2741 | HGNC ID: HGNC:4326 | Ensembl Gene: ENSG00000145888 | OMIM ID: 138491 |
| Drug and gene relationship at DGIdb | |||
Expression of GLRA1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GLRA1 | 2741 | 207972_at | -0.1549 | 0.5181 | |
| GSE20347 | GLRA1 | 2741 | 207972_at | -0.0271 | 0.7318 | |
| GSE23400 | GLRA1 | 2741 | 207972_at | -0.0418 | 0.1268 | |
| GSE26886 | GLRA1 | 2741 | 207972_at | 0.1072 | 0.3475 | |
| GSE29001 | GLRA1 | 2741 | 207972_at | -0.1388 | 0.3379 | |
| GSE38129 | GLRA1 | 2741 | 207972_at | -0.0979 | 0.0328 | |
| GSE45670 | GLRA1 | 2741 | 207972_at | 0.0391 | 0.7156 | |
| GSE53622 | GLRA1 | 2741 | 35891 | 0.0369 | 0.8464 | |
| GSE53624 | GLRA1 | 2741 | 35891 | 0.0334 | 0.7733 | |
| GSE63941 | GLRA1 | 2741 | 207972_at | 0.0822 | 0.5856 | |
| GSE77861 | GLRA1 | 2741 | 207972_at | -0.1355 | 0.2860 | |
| TCGA | GLRA1 | 2741 | RNAseq | 0.8355 | 0.4947 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by GLRA1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GLRA1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GLRA1 | 2741 | 1 | 12 | 17 | |
| GSE20123 | GLRA1 | 2741 | 1 | 12 | 17 | |
| GSE43470 | GLRA1 | 2741 | 2 | 10 | 31 | |
| GSE46452 | GLRA1 | 2741 | 0 | 27 | 32 | |
| GSE47630 | GLRA1 | 2741 | 0 | 20 | 20 | |
| GSE54993 | GLRA1 | 2741 | 9 | 1 | 60 | |
| GSE54994 | GLRA1 | 2741 | 2 | 15 | 36 | |
| GSE60625 | GLRA1 | 2741 | 0 | 0 | 11 | |
| GSE74703 | GLRA1 | 2741 | 2 | 8 | 26 | |
| GSE74704 | GLRA1 | 2741 | 1 | 7 | 12 | |
| TCGA | GLRA1 | 2741 | 5 | 37 | 54 |
Total number of gains: 23; Total number of losses: 149; Total Number of normals: 316.
Somatic mutations of GLRA1:
Generating mutation plots.
Highly correlated genes for GLRA1:
Showing top 20/239 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GLRA1 | ZNF287 | 0.743845 | 3 | 0 | 3 |
| GLRA1 | SFRP5 | 0.690945 | 3 | 0 | 3 |
| GLRA1 | PSG9 | 0.683292 | 4 | 0 | 3 |
| GLRA1 | SLC29A3 | 0.683197 | 3 | 0 | 3 |
| GLRA1 | DEFB108B | 0.67638 | 4 | 0 | 3 |
| GLRA1 | NEUROD4 | 0.664173 | 3 | 0 | 3 |
| GLRA1 | TFF1 | 0.651353 | 3 | 0 | 3 |
| GLRA1 | SLC6A20 | 0.648082 | 4 | 0 | 3 |
| GLRA1 | GPD1 | 0.643423 | 3 | 0 | 3 |
| GLRA1 | UTF1 | 0.642725 | 4 | 0 | 3 |
| GLRA1 | MUC2 | 0.642399 | 4 | 0 | 4 |
| GLRA1 | SLC10A2 | 0.638763 | 4 | 0 | 3 |
| GLRA1 | DGCR5 | 0.637939 | 3 | 0 | 3 |
| GLRA1 | KCNMB2 | 0.629176 | 5 | 0 | 3 |
| GLRA1 | SYN1 | 0.62598 | 3 | 0 | 3 |
| GLRA1 | FGF18 | 0.622758 | 5 | 0 | 4 |
| GLRA1 | CTNNA2 | 0.619468 | 4 | 0 | 3 |
| GLRA1 | NTRK3 | 0.616063 | 4 | 0 | 3 |
| GLRA1 | JAK3 | 0.615455 | 4 | 0 | 3 |
| GLRA1 | NHLH1 | 0.614688 | 3 | 0 | 3 |
For details and further investigation, click here
