| Full name: glycine receptor alpha 3 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 4q34.1 | ||
| Entrez ID: 8001 | HGNC ID: HGNC:4328 | Ensembl Gene: ENSG00000145451 | OMIM ID: 600421 |
| Drug and gene relationship at DGIdb | |||
Expression of GLRA3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GLRA3 | 8001 | 216021_s_at | -0.0244 | 0.9164 | |
| GSE20347 | GLRA3 | 8001 | 216021_s_at | -0.1320 | 0.0100 | |
| GSE23400 | GLRA3 | 8001 | 216021_s_at | -0.0383 | 0.0469 | |
| GSE26886 | GLRA3 | 8001 | 216021_s_at | 0.1193 | 0.2040 | |
| GSE29001 | GLRA3 | 8001 | 216021_s_at | -0.1847 | 0.0322 | |
| GSE38129 | GLRA3 | 8001 | 216021_s_at | -0.1290 | 0.0264 | |
| GSE45670 | GLRA3 | 8001 | 216021_s_at | -0.0043 | 0.9610 | |
| GSE53622 | GLRA3 | 8001 | 45432 | 0.1578 | 0.5504 | |
| GSE53624 | GLRA3 | 8001 | 45432 | 0.4846 | 0.0019 | |
| GSE63941 | GLRA3 | 8001 | 216021_s_at | 0.1490 | 0.1988 | |
| GSE77861 | GLRA3 | 8001 | 216021_s_at | -0.0936 | 0.2945 | |
| SRP133303 | GLRA3 | 8001 | RNAseq | 0.5785 | 0.0950 | |
| TCGA | GLRA3 | 8001 | RNAseq | 2.4546 | 0.0023 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by GLRA3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GLRA3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GLRA3 | 8001 | 1 | 10 | 19 | |
| GSE20123 | GLRA3 | 8001 | 1 | 10 | 19 | |
| GSE43470 | GLRA3 | 8001 | 0 | 13 | 30 | |
| GSE46452 | GLRA3 | 8001 | 1 | 36 | 22 | |
| GSE47630 | GLRA3 | 8001 | 0 | 22 | 18 | |
| GSE54993 | GLRA3 | 8001 | 10 | 0 | 60 | |
| GSE54994 | GLRA3 | 8001 | 2 | 12 | 39 | |
| GSE60625 | GLRA3 | 8001 | 0 | 0 | 11 | |
| GSE74703 | GLRA3 | 8001 | 0 | 11 | 25 | |
| GSE74704 | GLRA3 | 8001 | 0 | 5 | 15 | |
| TCGA | GLRA3 | 8001 | 10 | 37 | 49 |
Total number of gains: 25; Total number of losses: 156; Total Number of normals: 307.
Somatic mutations of GLRA3:
Generating mutation plots.
Highly correlated genes for GLRA3:
Showing top 20/243 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GLRA3 | CYP2E1 | 0.657382 | 3 | 0 | 3 |
| GLRA3 | NDOR1 | 0.651527 | 3 | 0 | 3 |
| GLRA3 | OR1A1 | 0.64983 | 3 | 0 | 3 |
| GLRA3 | HRH4 | 0.646262 | 3 | 0 | 3 |
| GLRA3 | KRT32 | 0.643455 | 4 | 0 | 4 |
| GLRA3 | NPY | 0.642596 | 3 | 0 | 3 |
| GLRA3 | TM4SF4 | 0.641866 | 3 | 0 | 3 |
| GLRA3 | CYP3A5 | 0.641304 | 4 | 0 | 4 |
| GLRA3 | HTR4 | 0.635784 | 3 | 0 | 3 |
| GLRA3 | RBPMS | 0.629957 | 4 | 0 | 3 |
| GLRA3 | GTF3C1 | 0.628919 | 3 | 0 | 3 |
| GLRA3 | PSCA | 0.627643 | 3 | 0 | 3 |
| GLRA3 | CEACAM1 | 0.625965 | 3 | 0 | 3 |
| GLRA3 | N4BP3 | 0.622494 | 3 | 0 | 3 |
| GLRA3 | SPP2 | 0.621189 | 3 | 0 | 3 |
| GLRA3 | CNR1 | 0.619261 | 4 | 0 | 3 |
| GLRA3 | HOPX | 0.616814 | 4 | 0 | 4 |
| GLRA3 | MCHR1 | 0.615573 | 3 | 0 | 3 |
| GLRA3 | FUT9 | 0.613459 | 4 | 0 | 3 |
| GLRA3 | SMPD1 | 0.612002 | 4 | 0 | 3 |
For details and further investigation, click here
