| Full name: MAM domain containing 4 | Alias Symbol: AEGP|DKFZp434M1411 | ||
| Type: protein-coding gene | Cytoband: 9q34.3 | ||
| Entrez ID: 158056 | HGNC ID: HGNC:24083 | Ensembl Gene: ENSG00000177943 | OMIM ID: 617208 |
| Drug and gene relationship at DGIdb | |||
Expression of MAMDC4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MAMDC4 | 158056 | 229473_at | -0.3061 | 0.4157 | |
| GSE26886 | MAMDC4 | 158056 | 229473_at | 0.0097 | 0.9606 | |
| GSE45670 | MAMDC4 | 158056 | 229473_at | 0.0865 | 0.4601 | |
| GSE53622 | MAMDC4 | 158056 | 73112 | 0.1840 | 0.0142 | |
| GSE53624 | MAMDC4 | 158056 | 73112 | -0.0057 | 0.9464 | |
| GSE63941 | MAMDC4 | 158056 | 229473_at | 0.1516 | 0.4703 | |
| GSE77861 | MAMDC4 | 158056 | 229473_at | -0.2783 | 0.0297 | |
| GSE97050 | MAMDC4 | 158056 | A_23_P71790 | 0.0713 | 0.7410 | |
| SRP007169 | MAMDC4 | 158056 | RNAseq | 0.4348 | 0.5888 | |
| SRP064894 | MAMDC4 | 158056 | RNAseq | 0.6588 | 0.0217 | |
| SRP133303 | MAMDC4 | 158056 | RNAseq | -0.6417 | 0.0012 | |
| SRP159526 | MAMDC4 | 158056 | RNAseq | 0.4922 | 0.4548 | |
| SRP193095 | MAMDC4 | 158056 | RNAseq | 0.2832 | 0.0617 | |
| SRP219564 | MAMDC4 | 158056 | RNAseq | -0.4060 | 0.1763 | |
| TCGA | MAMDC4 | 158056 | RNAseq | -0.3840 | 0.0263 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MAMDC4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MAMDC4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MAMDC4 | 158056 | 5 | 7 | 18 | |
| GSE20123 | MAMDC4 | 158056 | 5 | 7 | 18 | |
| GSE43470 | MAMDC4 | 158056 | 3 | 7 | 33 | |
| GSE46452 | MAMDC4 | 158056 | 6 | 13 | 40 | |
| GSE47630 | MAMDC4 | 158056 | 6 | 15 | 19 | |
| GSE54993 | MAMDC4 | 158056 | 3 | 3 | 64 | |
| GSE54994 | MAMDC4 | 158056 | 12 | 8 | 33 | |
| GSE60625 | MAMDC4 | 158056 | 0 | 0 | 11 | |
| GSE74703 | MAMDC4 | 158056 | 3 | 5 | 28 | |
| GSE74704 | MAMDC4 | 158056 | 3 | 5 | 12 | |
| TCGA | MAMDC4 | 158056 | 29 | 23 | 44 |
Total number of gains: 75; Total number of losses: 93; Total Number of normals: 320.
Somatic mutations of MAMDC4:
Generating mutation plots.
Highly correlated genes for MAMDC4:
Showing top 20/79 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MAMDC4 | KDM5D | 0.80783 | 3 | 0 | 3 |
| MAMDC4 | NDUFB3 | 0.760157 | 3 | 0 | 3 |
| MAMDC4 | ARHGEF15 | 0.750847 | 3 | 0 | 3 |
| MAMDC4 | EIF1AY | 0.749582 | 3 | 0 | 3 |
| MAMDC4 | COX7B | 0.737505 | 3 | 0 | 3 |
| MAMDC4 | OPTN | 0.737421 | 3 | 0 | 3 |
| MAMDC4 | APOL3 | 0.724466 | 3 | 0 | 3 |
| MAMDC4 | CR1L | 0.721898 | 4 | 0 | 4 |
| MAMDC4 | RBM5 | 0.714035 | 3 | 0 | 3 |
| MAMDC4 | WNK1 | 0.712135 | 3 | 0 | 3 |
| MAMDC4 | OPHN1 | 0.71114 | 4 | 0 | 4 |
| MAMDC4 | MACROD2 | 0.70794 | 3 | 0 | 3 |
| MAMDC4 | SARDH | 0.705329 | 3 | 0 | 3 |
| MAMDC4 | PKIA | 0.700855 | 3 | 0 | 3 |
| MAMDC4 | NTAN1 | 0.698798 | 3 | 0 | 3 |
| MAMDC4 | SLAMF6 | 0.692822 | 3 | 0 | 3 |
| MAMDC4 | GPATCH8 | 0.689816 | 3 | 0 | 3 |
| MAMDC4 | FAM149B1 | 0.687319 | 3 | 0 | 3 |
| MAMDC4 | MYT1 | 0.687313 | 3 | 0 | 3 |
| MAMDC4 | PPM1K | 0.67882 | 3 | 0 | 3 |
For details and further investigation, click here
