| Full name: apoptosis and caspase activation inhibitor | Alias Symbol: PDCD12 | ||
| Type: protein-coding gene | Cytoband: 15q14 | ||
| Entrez ID: 57099 | HGNC ID: HGNC:13509 | Ensembl Gene: ENSG00000169857 | OMIM ID: 605265 |
Expression of AVEN:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | AVEN | 57099 | 219366_at | -0.1201 | 0.8641 | |
| GSE20347 | AVEN | 57099 | 219366_at | -0.0663 | 0.8169 | |
| GSE23400 | AVEN | 57099 | 219366_at | 0.0962 | 0.0838 | |
| GSE26886 | AVEN | 57099 | 219366_at | 0.5806 | 0.0111 | |
| GSE29001 | AVEN | 57099 | 219366_at | 0.0002 | 0.9994 | |
| GSE38129 | AVEN | 57099 | 219366_at | 0.0213 | 0.9172 | |
| GSE45670 | AVEN | 57099 | 219366_at | -0.0240 | 0.9147 | |
| GSE53622 | AVEN | 57099 | 62773 | -0.1992 | 0.0240 | |
| GSE53624 | AVEN | 57099 | 62773 | 0.0652 | 0.3970 | |
| GSE63941 | AVEN | 57099 | 219366_at | -1.5288 | 0.0177 | |
| GSE77861 | AVEN | 57099 | 219366_at | -0.1586 | 0.6067 | |
| GSE97050 | AVEN | 57099 | A_23_P100074 | -0.0559 | 0.8460 | |
| SRP007169 | AVEN | 57099 | RNAseq | 1.3686 | 0.0697 | |
| SRP064894 | AVEN | 57099 | RNAseq | 0.2922 | 0.0907 | |
| SRP133303 | AVEN | 57099 | RNAseq | 0.2565 | 0.1400 | |
| SRP159526 | AVEN | 57099 | RNAseq | -0.0609 | 0.8820 | |
| SRP193095 | AVEN | 57099 | RNAseq | -0.0620 | 0.6189 | |
| SRP219564 | AVEN | 57099 | RNAseq | -0.1413 | 0.6998 | |
| TCGA | AVEN | 57099 | RNAseq | -0.0025 | 0.9703 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by AVEN expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of AVEN:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | AVEN | 57099 | 3 | 6 | 21 | |
| GSE20123 | AVEN | 57099 | 3 | 6 | 21 | |
| GSE43470 | AVEN | 57099 | 4 | 4 | 35 | |
| GSE46452 | AVEN | 57099 | 3 | 7 | 49 | |
| GSE47630 | AVEN | 57099 | 8 | 11 | 21 | |
| GSE54993 | AVEN | 57099 | 4 | 6 | 60 | |
| GSE54994 | AVEN | 57099 | 5 | 8 | 40 | |
| GSE60625 | AVEN | 57099 | 4 | 0 | 7 | |
| GSE74703 | AVEN | 57099 | 4 | 3 | 29 | |
| GSE74704 | AVEN | 57099 | 2 | 5 | 13 | |
| TCGA | AVEN | 57099 | 14 | 16 | 66 |
Total number of gains: 54; Total number of losses: 72; Total Number of normals: 362.
Somatic mutations of AVEN:
Generating mutation plots.
Highly correlated genes for AVEN:
Showing top 20/300 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| AVEN | ENTPD3 | 0.761239 | 3 | 0 | 3 |
| AVEN | CPT1A | 0.756498 | 3 | 0 | 3 |
| AVEN | SGTB | 0.72098 | 3 | 0 | 3 |
| AVEN | TXNRD1 | 0.714565 | 3 | 0 | 3 |
| AVEN | TRAF3IP1 | 0.714204 | 3 | 0 | 3 |
| AVEN | SLC44A1 | 0.711102 | 3 | 0 | 3 |
| AVEN | RPP14 | 0.70503 | 3 | 0 | 3 |
| AVEN | VPS18 | 0.699204 | 3 | 0 | 3 |
| AVEN | TTC37 | 0.697284 | 3 | 0 | 3 |
| AVEN | HSPA9 | 0.695929 | 3 | 0 | 3 |
| AVEN | PDLIM2 | 0.691247 | 3 | 0 | 3 |
| AVEN | EMC7 | 0.690349 | 10 | 0 | 9 |
| AVEN | CYP20A1 | 0.682348 | 3 | 0 | 3 |
| AVEN | NUP88 | 0.681238 | 3 | 0 | 3 |
| AVEN | LRRC57 | 0.678745 | 4 | 0 | 4 |
| AVEN | PRCP | 0.676676 | 3 | 0 | 3 |
| AVEN | PODN | 0.675983 | 3 | 0 | 3 |
| AVEN | WDR61 | 0.672405 | 7 | 0 | 7 |
| AVEN | CYTH3 | 0.670582 | 3 | 0 | 3 |
| AVEN | MRPL39 | 0.670169 | 3 | 0 | 3 |
For details and further investigation, click here
