| Full name: G protein-coupled receptor 20 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 8q24.3 | ||
| Entrez ID: 2843 | HGNC ID: HGNC:4475 | Ensembl Gene: ENSG00000204882 | OMIM ID: 601908 |
| Drug and gene relationship at DGIdb | |||
Expression of GPR20:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE20347 | GPR20 | 2843 | 214510_at | 0.1515 | 0.2041 | |
| GSE23400 | GPR20 | 2843 | 214510_at | -0.1850 | 0.0000 | |
| GSE29001 | GPR20 | 2843 | 214510_at | -0.1044 | 0.5722 | |
| GSE38129 | GPR20 | 2843 | 214510_at | -0.2182 | 0.0716 | |
| GSE53622 | GPR20 | 2843 | 52573 | -0.6775 | 0.0000 | |
| GSE53624 | GPR20 | 2843 | 52573 | -0.6450 | 0.0000 | |
| GSE97050 | GPR20 | 2843 | A_23_P159237 | -0.6273 | 0.2852 | |
| SRP133303 | GPR20 | 2843 | RNAseq | -1.1445 | 0.0161 | |
| TCGA | GPR20 | 2843 | RNAseq | -1.9052 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by GPR20 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GPR20:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GPR20 | 2843 | 17 | 0 | 13 | |
| GSE20123 | GPR20 | 2843 | 16 | 0 | 14 | |
| GSE43470 | GPR20 | 2843 | 20 | 2 | 21 | |
| GSE46452 | GPR20 | 2843 | 27 | 0 | 32 | |
| GSE47630 | GPR20 | 2843 | 24 | 0 | 16 | |
| GSE54993 | GPR20 | 2843 | 0 | 25 | 45 | |
| GSE54994 | GPR20 | 2843 | 39 | 1 | 13 | |
| GSE60625 | GPR20 | 2843 | 3 | 4 | 4 | |
| GSE74703 | GPR20 | 2843 | 18 | 1 | 17 | |
| GSE74704 | GPR20 | 2843 | 10 | 0 | 10 | |
| TCGA | GPR20 | 2843 | 64 | 2 | 30 |
Total number of gains: 238; Total number of losses: 35; Total Number of normals: 215.
Somatic mutations of GPR20:
Generating mutation plots.
Highly correlated genes for GPR20:
Showing top 20/302 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GPR20 | PPP1R14A | 0.772591 | 3 | 0 | 3 |
| GPR20 | ADCY5 | 0.76013 | 3 | 0 | 3 |
| GPR20 | NEGR1 | 0.749692 | 3 | 0 | 3 |
| GPR20 | CADM2 | 0.730726 | 3 | 0 | 3 |
| GPR20 | CYP21A2 | 0.704456 | 3 | 0 | 3 |
| GPR20 | MYOCD | 0.691672 | 3 | 0 | 3 |
| GPR20 | RBFOX3 | 0.683033 | 3 | 0 | 3 |
| GPR20 | PLAC9 | 0.680383 | 3 | 0 | 3 |
| GPR20 | DACT3 | 0.674224 | 3 | 0 | 3 |
| GPR20 | SMOC2 | 0.670106 | 3 | 0 | 3 |
| GPR20 | LGI4 | 0.669395 | 3 | 0 | 3 |
| GPR20 | MYOM1 | 0.669353 | 6 | 0 | 5 |
| GPR20 | SH3BGR | 0.661372 | 4 | 0 | 4 |
| GPR20 | LTBP4 | 0.653569 | 5 | 0 | 4 |
| GPR20 | RGS7BP | 0.652501 | 3 | 0 | 3 |
| GPR20 | LRRTM1 | 0.652332 | 4 | 0 | 4 |
| GPR20 | CACNA1H | 0.651694 | 4 | 0 | 4 |
| GPR20 | INMT | 0.646685 | 3 | 0 | 3 |
| GPR20 | PYGM | 0.642566 | 6 | 0 | 6 |
| GPR20 | ZBTB40 | 0.642132 | 3 | 0 | 3 |
For details and further investigation, click here
