| Full name: G protein regulated inducer of neurite outgrowth 2 | Alias Symbol: MGC15171 | ||
| Type: protein-coding gene | Cytoband: 10q11.22 | ||
| Entrez ID: 9721 | HGNC ID: HGNC:23730 | Ensembl Gene: ENSG00000204175 | OMIM ID: 611240 |
| Drug and gene relationship at DGIdb | |||
Expression of GPRIN2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GPRIN2 | 9721 | 206747_at | 0.1587 | 0.6429 | |
| GSE20347 | GPRIN2 | 9721 | 206747_at | -0.2124 | 0.1026 | |
| GSE23400 | GPRIN2 | 9721 | 206747_at | -0.1238 | 0.0067 | |
| GSE26886 | GPRIN2 | 9721 | 206747_at | -0.5331 | 0.0152 | |
| GSE29001 | GPRIN2 | 9721 | 206747_at | -0.7040 | 0.0380 | |
| GSE38129 | GPRIN2 | 9721 | 206747_at | -0.2075 | 0.2662 | |
| GSE45670 | GPRIN2 | 9721 | 206747_at | -0.1601 | 0.2785 | |
| GSE53622 | GPRIN2 | 9721 | 59024 | -0.5578 | 0.0005 | |
| GSE53624 | GPRIN2 | 9721 | 59024 | -0.9131 | 0.0000 | |
| GSE63941 | GPRIN2 | 9721 | 206747_at | 0.9171 | 0.1069 | |
| GSE77861 | GPRIN2 | 9721 | 206747_at | -0.2681 | 0.0884 | |
| GSE97050 | GPRIN2 | 9721 | A_33_P3285299 | -0.0894 | 0.8251 | |
| SRP007169 | GPRIN2 | 9721 | RNAseq | -3.4173 | 0.0000 | |
| SRP008496 | GPRIN2 | 9721 | RNAseq | -1.3951 | 0.1187 | |
| SRP064894 | GPRIN2 | 9721 | RNAseq | -1.6625 | 0.0000 | |
| SRP133303 | GPRIN2 | 9721 | RNAseq | -1.7011 | 0.0000 | |
| SRP159526 | GPRIN2 | 9721 | RNAseq | -1.0902 | 0.0393 | |
| SRP193095 | GPRIN2 | 9721 | RNAseq | -1.1049 | 0.0004 | |
| SRP219564 | GPRIN2 | 9721 | RNAseq | -1.3810 | 0.1918 | |
| TCGA | GPRIN2 | 9721 | RNAseq | -0.5606 | 0.0297 |
Upregulated datasets: 0; Downregulated datasets: 5.
Survival by GPRIN2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GPRIN2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GPRIN2 | 9721 | 3 | 5 | 22 | |
| GSE20123 | GPRIN2 | 9721 | 3 | 5 | 22 | |
| GSE43470 | GPRIN2 | 9721 | 2 | 6 | 35 | |
| GSE46452 | GPRIN2 | 9721 | 0 | 13 | 46 | |
| GSE47630 | GPRIN2 | 9721 | 4 | 12 | 24 | |
| GSE54993 | GPRIN2 | 9721 | 9 | 0 | 61 | |
| GSE54994 | GPRIN2 | 9721 | 2 | 10 | 41 | |
| GSE60625 | GPRIN2 | 9721 | 0 | 0 | 11 | |
| GSE74703 | GPRIN2 | 9721 | 2 | 3 | 31 | |
| GSE74704 | GPRIN2 | 9721 | 2 | 4 | 14 | |
| TCGA | GPRIN2 | 9721 | 16 | 18 | 62 |
Total number of gains: 43; Total number of losses: 76; Total Number of normals: 369.
Somatic mutations of GPRIN2:
Generating mutation plots.
Highly correlated genes for GPRIN2:
Showing top 20/188 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GPRIN2 | CAPNS2 | 0.670651 | 3 | 0 | 3 |
| GPRIN2 | KLHDC7A | 0.657589 | 3 | 0 | 3 |
| GPRIN2 | TADA2B | 0.618847 | 4 | 0 | 3 |
| GPRIN2 | PRKCI | 0.60979 | 4 | 0 | 3 |
| GPRIN2 | DHCR24 | 0.600918 | 5 | 0 | 4 |
| GPRIN2 | KIAA2026 | 0.596981 | 3 | 0 | 3 |
| GPRIN2 | CDIP1 | 0.595698 | 4 | 0 | 3 |
| GPRIN2 | ADCY6 | 0.595475 | 6 | 0 | 5 |
| GPRIN2 | H6PD | 0.590183 | 5 | 0 | 5 |
| GPRIN2 | ZBTB42 | 0.58458 | 4 | 0 | 4 |
| GPRIN2 | MINK1 | 0.580168 | 5 | 0 | 5 |
| GPRIN2 | PRPSAP1 | 0.578814 | 3 | 0 | 3 |
| GPRIN2 | MACC1 | 0.577961 | 5 | 0 | 4 |
| GPRIN2 | PLA2G3 | 0.572079 | 4 | 0 | 3 |
| GPRIN2 | KLRD1 | 0.566302 | 4 | 0 | 3 |
| GPRIN2 | MOSPD3 | 0.565669 | 8 | 0 | 6 |
| GPRIN2 | PIDD1 | 0.564399 | 7 | 0 | 6 |
| GPRIN2 | SYTL1 | 0.562713 | 7 | 0 | 4 |
| GPRIN2 | DCAF5 | 0.562218 | 5 | 0 | 4 |
| GPRIN2 | PWWP2B | 0.562215 | 7 | 0 | 6 |
For details and further investigation, click here
