DCAF5

 

Full name: DDB1 and CUL4 associated factor 5 Alias Symbol: BCRP2|D14S1461E|BCRG2|KIAA1824
Type: protein-coding gene Cytoband: 14q24.1
Entrez ID: 8816 HGNC ID: HGNC:20224 Ensembl Gene: ENSG00000139990 OMIM ID: 603812
Drug and gene relationship at DGIdb

 

Expression of DCAF5:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 DCAF5 8816 224703_at -0.0571 0.9437
GSE26886 DCAF5 8816 224696_s_at -0.7445 0.0132
GSE45670 DCAF5 8816 224703_at -0.1173 0.3228
GSE53622 DCAF5 8816 80806 0.3323 0.0013
GSE53624 DCAF5 8816 18812 -0.6838 0.0000
GSE63941 DCAF5 8816 224703_at 0.2337 0.6164
GSE77861 DCAF5 8816 224703_at -0.1349 0.7918
GSE97050 DCAF5 8816 A_33_P3384667 0.6049 0.2578
SRP007169 DCAF5 8816 RNAseq -0.2877 0.4141
SRP008496 DCAF5 8816 RNAseq 0.0099 0.9710
SRP064894 DCAF5 8816 RNAseq -0.1546 0.2917
SRP133303 DCAF5 8816 RNAseq -0.0732 0.6641
SRP159526 DCAF5 8816 RNAseq -0.5590 0.0644
SRP193095 DCAF5 8816 RNAseq -0.1967 0.0633
SRP219564 DCAF5 8816 RNAseq -0.0955 0.7487
TCGA DCAF5 8816 RNAseq -0.0835 0.0672

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by DCAF5 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of DCAF5:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 DCAF5 8816 8 3 19
GSE20123 DCAF5 8816 8 3 19
GSE43470 DCAF5 8816 8 3 32
GSE46452 DCAF5 8816 16 3 40
GSE47630 DCAF5 8816 11 9 20
GSE54993 DCAF5 8816 3 9 58
GSE54994 DCAF5 8816 18 5 30
GSE60625 DCAF5 8816 0 2 9
GSE74703 DCAF5 8816 7 3 26
GSE74704 DCAF5 8816 3 3 14
TCGA DCAF5 8816 32 16 48

Total number of gains: 114; Total number of losses: 59; Total Number of normals: 315.  


 

Somatic mutations of DCAF5:

 

Generating mutation plots.

 

Highly correlated genes for DCAF5:

 

Showing top 20/91 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
DCAF5UBAC20.67258303
DCAF5EIF50.669604303
DCAF5GTF2A10.666133303
DCAF5MIOS0.661588404
DCAF5VTI1B0.65195404
DCAF5MREG0.644473303
DCAF5ANKZF10.638355303
DCAF5LINC009580.637714303
DCAF5RBM8A0.628487403
DCAF5DUSP110.626613403
DCAF5SMIM140.625433303
DCAF5RNF110.624064303
DCAF5PANK20.621769303
DCAF5TMED30.619718303
DCAF5ATXN70.618582303
DCAF5ZFYVE10.617431504
DCAF5ZFYVE210.605107505
DCAF5PRPF390.604447403
DCAF5DAAM10.604348404
DCAF5CWH430.600786303

For details and further investigation, click here