| Full name: HECT domain E3 ubiquitin protein ligase 4 | Alias Symbol: FLJ34154|KIAA0614 | ||
| Type: protein-coding gene | Cytoband: 12q24.13 | ||
| Entrez ID: 283450 | HGNC ID: HGNC:26611 | Ensembl Gene: ENSG00000173064 | OMIM ID: |
Expression of HECTD4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HECTD4 | 283450 | 211034_s_at | -0.3791 | 0.3020 | |
| GSE20347 | HECTD4 | 283450 | 211034_s_at | -0.5893 | 0.0000 | |
| GSE23400 | HECTD4 | 283450 | 211034_s_at | -0.4685 | 0.0000 | |
| GSE26886 | HECTD4 | 283450 | 211034_s_at | -0.6321 | 0.0194 | |
| GSE29001 | HECTD4 | 283450 | 211034_s_at | -0.7616 | 0.0013 | |
| GSE38129 | HECTD4 | 283450 | 211034_s_at | -0.5976 | 0.0000 | |
| GSE45670 | HECTD4 | 283450 | 211034_s_at | -0.5134 | 0.0019 | |
| GSE53622 | HECTD4 | 283450 | 36253 | -0.7370 | 0.0000 | |
| GSE53624 | HECTD4 | 283450 | 62441 | -0.9057 | 0.0000 | |
| GSE63941 | HECTD4 | 283450 | 211034_s_at | -0.2522 | 0.4261 | |
| GSE77861 | HECTD4 | 283450 | 211034_s_at | -0.2732 | 0.1636 | |
| SRP007169 | HECTD4 | 283450 | RNAseq | -0.2427 | 0.5277 | |
| SRP008496 | HECTD4 | 283450 | RNAseq | -0.9116 | 0.0640 | |
| SRP064894 | HECTD4 | 283450 | RNAseq | -0.9862 | 0.0001 | |
| SRP133303 | HECTD4 | 283450 | RNAseq | -0.4327 | 0.0234 | |
| SRP159526 | HECTD4 | 283450 | RNAseq | -0.6300 | 0.0128 | |
| SRP193095 | HECTD4 | 283450 | RNAseq | -0.4481 | 0.0009 | |
| SRP219564 | HECTD4 | 283450 | RNAseq | -0.9914 | 0.0058 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by HECTD4 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of HECTD4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HECTD4 | 283450 | 5 | 3 | 22 | |
| GSE20123 | HECTD4 | 283450 | 4 | 3 | 23 | |
| GSE43470 | HECTD4 | 283450 | 2 | 1 | 40 | |
| GSE46452 | HECTD4 | 283450 | 9 | 1 | 49 | |
| GSE47630 | HECTD4 | 283450 | 9 | 3 | 28 | |
| GSE54993 | HECTD4 | 283450 | 0 | 5 | 65 | |
| GSE54994 | HECTD4 | 283450 | 4 | 2 | 47 | |
| GSE60625 | HECTD4 | 283450 | 0 | 0 | 11 | |
| GSE74703 | HECTD4 | 283450 | 2 | 0 | 34 | |
| GSE74704 | HECTD4 | 283450 | 2 | 2 | 16 | |
| TCGA | HECTD4 | 283450 | 22 | 11 | 63 |
Total number of gains: 59; Total number of losses: 31; Total Number of normals: 398.
Somatic mutations of HECTD4:
Generating mutation plots.
Highly correlated genes for HECTD4:
Showing top 20/1076 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HECTD4 | KIAA0232 | 0.712898 | 10 | 0 | 10 |
| HECTD4 | CPEB3 | 0.706565 | 9 | 0 | 9 |
| HECTD4 | ZSWIM8 | 0.703538 | 7 | 0 | 6 |
| HECTD4 | ARHGEF10L | 0.702998 | 9 | 0 | 8 |
| HECTD4 | KAT2B | 0.682976 | 11 | 0 | 10 |
| HECTD4 | HDHD2 | 0.681865 | 4 | 0 | 4 |
| HECTD4 | MLLT10 | 0.680587 | 4 | 0 | 4 |
| HECTD4 | EPB41 | 0.6804 | 5 | 0 | 5 |
| HECTD4 | ACOX3 | 0.67947 | 9 | 0 | 9 |
| HECTD4 | CIPC | 0.674859 | 5 | 0 | 4 |
| HECTD4 | ECHDC2 | 0.673296 | 10 | 0 | 10 |
| HECTD4 | DMXL1 | 0.672078 | 10 | 0 | 9 |
| HECTD4 | GPBP1 | 0.667679 | 4 | 0 | 4 |
| HECTD4 | ABR | 0.666238 | 10 | 0 | 9 |
| HECTD4 | RIPK4 | 0.665513 | 6 | 0 | 6 |
| HECTD4 | ANKRD13A | 0.665057 | 5 | 0 | 5 |
| HECTD4 | LINC01023 | 0.663182 | 4 | 0 | 4 |
| HECTD4 | SASH1 | 0.661071 | 11 | 0 | 9 |
| HECTD4 | AFF1 | 0.659244 | 8 | 0 | 7 |
| HECTD4 | SENP7 | 0.657203 | 3 | 0 | 3 |
For details and further investigation, click here
