| Full name: SUMO specific peptidase 7 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 3q12.3 | ||
| Entrez ID: 57337 | HGNC ID: HGNC:30402 | Ensembl Gene: ENSG00000138468 | OMIM ID: 612846 |
| Drug and gene relationship at DGIdb | |||
Expression of SENP7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SENP7 | 57337 | 223444_at | -0.1536 | 0.6950 | |
| GSE20347 | SENP7 | 57337 | 220735_s_at | -0.0189 | 0.8030 | |
| GSE23400 | SENP7 | 57337 | 220735_s_at | 0.0090 | 0.7715 | |
| GSE26886 | SENP7 | 57337 | 223444_at | -0.4407 | 0.1024 | |
| GSE29001 | SENP7 | 57337 | 220735_s_at | 0.0430 | 0.7512 | |
| GSE38129 | SENP7 | 57337 | 220735_s_at | -0.0296 | 0.6830 | |
| GSE45670 | SENP7 | 57337 | 223444_at | -0.2987 | 0.0842 | |
| GSE53622 | SENP7 | 57337 | 30653 | -0.0268 | 0.8135 | |
| GSE53624 | SENP7 | 57337 | 30653 | -0.0932 | 0.2929 | |
| GSE63941 | SENP7 | 57337 | 223444_at | -0.4013 | 0.4033 | |
| GSE77861 | SENP7 | 57337 | 223444_at | -0.2761 | 0.4386 | |
| GSE97050 | SENP7 | 57337 | A_24_P265856 | -0.0503 | 0.8635 | |
| SRP007169 | SENP7 | 57337 | RNAseq | 0.3517 | 0.4976 | |
| SRP008496 | SENP7 | 57337 | RNAseq | 0.3227 | 0.4411 | |
| SRP064894 | SENP7 | 57337 | RNAseq | -0.1811 | 0.4106 | |
| SRP133303 | SENP7 | 57337 | RNAseq | -0.2791 | 0.0346 | |
| SRP159526 | SENP7 | 57337 | RNAseq | -0.3381 | 0.2030 | |
| SRP193095 | SENP7 | 57337 | RNAseq | -0.0982 | 0.3676 | |
| SRP219564 | SENP7 | 57337 | RNAseq | -0.3484 | 0.2783 | |
| TCGA | SENP7 | 57337 | RNAseq | -0.2430 | 0.0008 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SENP7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SENP7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SENP7 | 57337 | 18 | 1 | 11 | |
| GSE20123 | SENP7 | 57337 | 17 | 1 | 12 | |
| GSE43470 | SENP7 | 57337 | 19 | 1 | 23 | |
| GSE46452 | SENP7 | 57337 | 12 | 6 | 41 | |
| GSE47630 | SENP7 | 57337 | 16 | 6 | 18 | |
| GSE54993 | SENP7 | 57337 | 2 | 5 | 63 | |
| GSE54994 | SENP7 | 57337 | 27 | 5 | 21 | |
| GSE60625 | SENP7 | 57337 | 0 | 6 | 5 | |
| GSE74703 | SENP7 | 57337 | 15 | 1 | 20 | |
| GSE74704 | SENP7 | 57337 | 14 | 1 | 5 | |
| TCGA | SENP7 | 57337 | 48 | 9 | 39 |
Total number of gains: 188; Total number of losses: 42; Total Number of normals: 258.
Somatic mutations of SENP7:
Generating mutation plots.
Highly correlated genes for SENP7:
Showing top 20/63 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SENP7 | LNX2 | 0.695075 | 3 | 0 | 3 |
| SENP7 | N4BP2L2 | 0.682873 | 3 | 0 | 3 |
| SENP7 | COG3 | 0.66091 | 3 | 0 | 3 |
| SENP7 | HECTD4 | 0.657203 | 3 | 0 | 3 |
| SENP7 | RNF180 | 0.655054 | 3 | 0 | 3 |
| SENP7 | ALDH6A1 | 0.650655 | 3 | 0 | 3 |
| SENP7 | LRSAM1 | 0.648666 | 3 | 0 | 3 |
| SENP7 | INSC | 0.636154 | 3 | 0 | 3 |
| SENP7 | AGTPBP1 | 0.628911 | 3 | 0 | 3 |
| SENP7 | ZNF573 | 0.625877 | 3 | 0 | 3 |
| SENP7 | ZHX1 | 0.62484 | 4 | 0 | 3 |
| SENP7 | B3GNT2 | 0.618665 | 4 | 0 | 4 |
| SENP7 | EP300-AS1 | 0.614665 | 3 | 0 | 3 |
| SENP7 | LTN1 | 0.609402 | 4 | 0 | 4 |
| SENP7 | EAF1 | 0.602347 | 3 | 0 | 3 |
| SENP7 | PCNP | 0.596475 | 7 | 0 | 6 |
| SENP7 | PAN3 | 0.59103 | 5 | 0 | 3 |
| SENP7 | APOB | 0.590799 | 5 | 0 | 4 |
| SENP7 | CPEB4 | 0.589577 | 4 | 0 | 3 |
| SENP7 | GPBP1 | 0.586635 | 4 | 0 | 3 |
For details and further investigation, click here
