| Full name: VAMP associated protein A | Alias Symbol: hVAP-33|VAP-A | ||
| Type: protein-coding gene | Cytoband: 18p11.22 | ||
| Entrez ID: 9218 | HGNC ID: HGNC:12648 | Ensembl Gene: ENSG00000101558 | OMIM ID: 605703 |
| Drug and gene relationship at DGIdb | |||
Expression of VAPA:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | VAPA | 9218 | 208780_x_at | -0.0116 | 0.9873 | |
| GSE20347 | VAPA | 9218 | 208780_x_at | -0.1568 | 0.2592 | |
| GSE23400 | VAPA | 9218 | 208780_x_at | 0.0205 | 0.7709 | |
| GSE26886 | VAPA | 9218 | 208780_x_at | -0.4334 | 0.0072 | |
| GSE29001 | VAPA | 9218 | 208780_x_at | -0.0566 | 0.7909 | |
| GSE38129 | VAPA | 9218 | 208780_x_at | -0.0755 | 0.5930 | |
| GSE45670 | VAPA | 9218 | 208780_x_at | -0.0185 | 0.8987 | |
| GSE53622 | VAPA | 9218 | 75290 | -0.2269 | 0.0005 | |
| GSE53624 | VAPA | 9218 | 75290 | -0.0758 | 0.2710 | |
| GSE63941 | VAPA | 9218 | 208780_x_at | 0.3566 | 0.4033 | |
| GSE77861 | VAPA | 9218 | 208780_x_at | -0.1552 | 0.3049 | |
| GSE97050 | VAPA | 9218 | A_23_P382199 | -0.0261 | 0.9381 | |
| SRP007169 | VAPA | 9218 | RNAseq | -0.7386 | 0.0379 | |
| SRP008496 | VAPA | 9218 | RNAseq | -0.9017 | 0.0000 | |
| SRP064894 | VAPA | 9218 | RNAseq | -0.3679 | 0.0252 | |
| SRP133303 | VAPA | 9218 | RNAseq | -0.0256 | 0.8503 | |
| SRP159526 | VAPA | 9218 | RNAseq | -0.3209 | 0.1546 | |
| SRP193095 | VAPA | 9218 | RNAseq | -0.4083 | 0.0023 | |
| SRP219564 | VAPA | 9218 | RNAseq | -0.5018 | 0.0172 | |
| TCGA | VAPA | 9218 | RNAseq | -0.0535 | 0.2060 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by VAPA expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of VAPA:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | VAPA | 9218 | 6 | 3 | 21 | |
| GSE20123 | VAPA | 9218 | 6 | 3 | 21 | |
| GSE43470 | VAPA | 9218 | 3 | 6 | 34 | |
| GSE46452 | VAPA | 9218 | 3 | 21 | 35 | |
| GSE47630 | VAPA | 9218 | 7 | 17 | 16 | |
| GSE54993 | VAPA | 9218 | 6 | 2 | 62 | |
| GSE54994 | VAPA | 9218 | 8 | 8 | 37 | |
| GSE60625 | VAPA | 9218 | 0 | 4 | 7 | |
| GSE74703 | VAPA | 9218 | 2 | 4 | 30 | |
| GSE74704 | VAPA | 9218 | 4 | 2 | 14 | |
| TCGA | VAPA | 9218 | 29 | 23 | 44 |
Total number of gains: 74; Total number of losses: 93; Total Number of normals: 321.
Somatic mutations of VAPA:
Generating mutation plots.
Highly correlated genes for VAPA:
Showing top 20/285 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| VAPA | CRYBG3 | 0.753277 | 3 | 0 | 3 |
| VAPA | RIOK2 | 0.742461 | 3 | 0 | 3 |
| VAPA | PROS1 | 0.741383 | 3 | 0 | 3 |
| VAPA | NCKAP1 | 0.727279 | 4 | 0 | 3 |
| VAPA | AKIRIN2 | 0.726995 | 3 | 0 | 3 |
| VAPA | HMGN3 | 0.724442 | 3 | 0 | 3 |
| VAPA | ZC3H15 | 0.71977 | 3 | 0 | 3 |
| VAPA | PPP4R1 | 0.712681 | 12 | 0 | 11 |
| VAPA | AFAP1L1 | 0.707385 | 3 | 0 | 3 |
| VAPA | AKIP1 | 0.705964 | 3 | 0 | 3 |
| VAPA | RPL36AL | 0.705151 | 3 | 0 | 3 |
| VAPA | BDP1 | 0.701248 | 3 | 0 | 3 |
| VAPA | UBE2F | 0.700114 | 5 | 0 | 4 |
| VAPA | CREBBP | 0.693814 | 3 | 0 | 3 |
| VAPA | DHX29 | 0.691854 | 3 | 0 | 3 |
| VAPA | NAPG | 0.691598 | 9 | 0 | 8 |
| VAPA | PSME1 | 0.691476 | 3 | 0 | 3 |
| VAPA | RABGAP1L | 0.691332 | 3 | 0 | 3 |
| VAPA | NEDD8 | 0.686111 | 4 | 0 | 3 |
| VAPA | CHMP1B | 0.680064 | 9 | 0 | 9 |
For details and further investigation, click here
