| Full name: DLG associated protein 1 | Alias Symbol: GKAP|SAPAP1|DAP-1 | ||
| Type: protein-coding gene | Cytoband: 18p11.31 | ||
| Entrez ID: 9229 | HGNC ID: HGNC:2905 | Ensembl Gene: ENSG00000170579 | OMIM ID: 605445 |
| Drug and gene relationship at DGIdb | |||
Expression of DLGAP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DLGAP1 | 9229 | 210750_s_at | -0.0473 | 0.8348 | |
| GSE20347 | DLGAP1 | 9229 | 210750_s_at | -0.0339 | 0.7108 | |
| GSE23400 | DLGAP1 | 9229 | 210750_s_at | -0.0967 | 0.0007 | |
| GSE26886 | DLGAP1 | 9229 | 210750_s_at | -0.0590 | 0.7554 | |
| GSE29001 | DLGAP1 | 9229 | 210750_s_at | -0.1918 | 0.1405 | |
| GSE38129 | DLGAP1 | 9229 | 210750_s_at | -0.1393 | 0.0364 | |
| GSE45670 | DLGAP1 | 9229 | 210750_s_at | 0.1256 | 0.3463 | |
| GSE53622 | DLGAP1 | 9229 | 89788 | -0.1747 | 0.5598 | |
| GSE53624 | DLGAP1 | 9229 | 89788 | -0.2667 | 0.2910 | |
| GSE63941 | DLGAP1 | 9229 | 210750_s_at | 0.3168 | 0.0698 | |
| GSE77861 | DLGAP1 | 9229 | 210750_s_at | -0.0808 | 0.4403 | |
| SRP133303 | DLGAP1 | 9229 | RNAseq | -0.0715 | 0.8825 | |
| SRP159526 | DLGAP1 | 9229 | RNAseq | 2.0491 | 0.0244 | |
| TCGA | DLGAP1 | 9229 | RNAseq | -0.1485 | 0.7778 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by DLGAP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DLGAP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DLGAP1 | 9229 | 9 | 2 | 19 | |
| GSE20123 | DLGAP1 | 9229 | 9 | 2 | 19 | |
| GSE43470 | DLGAP1 | 9229 | 4 | 5 | 34 | |
| GSE46452 | DLGAP1 | 9229 | 3 | 21 | 35 | |
| GSE47630 | DLGAP1 | 9229 | 8 | 17 | 15 | |
| GSE54993 | DLGAP1 | 9229 | 5 | 5 | 60 | |
| GSE54994 | DLGAP1 | 9229 | 11 | 9 | 33 | |
| GSE60625 | DLGAP1 | 9229 | 0 | 4 | 7 | |
| GSE74703 | DLGAP1 | 9229 | 3 | 3 | 30 | |
| GSE74704 | DLGAP1 | 9229 | 6 | 1 | 13 | |
| TCGA | DLGAP1 | 9229 | 37 | 16 | 43 |
Total number of gains: 95; Total number of losses: 85; Total Number of normals: 308.
Somatic mutations of DLGAP1:
Generating mutation plots.
Highly correlated genes for DLGAP1:
Showing top 20/747 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DLGAP1 | MOSPD3 | 0.684731 | 3 | 0 | 3 |
| DLGAP1 | NMNAT2 | 0.677427 | 3 | 0 | 3 |
| DLGAP1 | ZMAT4 | 0.667543 | 3 | 0 | 3 |
| DLGAP1 | OR2H2 | 0.663555 | 5 | 0 | 5 |
| DLGAP1 | RABEP2 | 0.66202 | 4 | 0 | 4 |
| DLGAP1 | RHAG | 0.655271 | 3 | 0 | 3 |
| DLGAP1 | ASCL3 | 0.654775 | 7 | 0 | 7 |
| DLGAP1 | ADAM11 | 0.654644 | 6 | 0 | 6 |
| DLGAP1 | ADPRH | 0.653794 | 5 | 0 | 5 |
| DLGAP1 | CAMK2B | 0.653571 | 6 | 0 | 6 |
| DLGAP1 | UTF1 | 0.65161 | 3 | 0 | 3 |
| DLGAP1 | SRCAP | 0.651139 | 3 | 0 | 3 |
| DLGAP1 | CXCR6 | 0.650872 | 3 | 0 | 3 |
| DLGAP1 | VIPR2 | 0.650607 | 6 | 0 | 5 |
| DLGAP1 | DND1 | 0.650028 | 3 | 0 | 3 |
| DLGAP1 | VGF | 0.648018 | 3 | 0 | 3 |
| DLGAP1 | CD5L | 0.645759 | 3 | 0 | 3 |
| DLGAP1 | AMHR2 | 0.645264 | 8 | 0 | 7 |
| DLGAP1 | PNOC | 0.643942 | 3 | 0 | 3 |
| DLGAP1 | CNTD2 | 0.64132 | 8 | 0 | 7 |
For details and further investigation, click here
