| Full name: homeobox A2 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 7p15.2 | ||
| Entrez ID: 3199 | HGNC ID: HGNC:5103 | Ensembl Gene: ENSG00000105996 | OMIM ID: 604685 |
| Drug and gene relationship at DGIdb | |||
Expression of HOXA2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HOXA2 | 3199 | 214457_at | -0.7312 | 0.0504 | |
| GSE20347 | HOXA2 | 3199 | 214457_at | -0.1577 | 0.1941 | |
| GSE23400 | HOXA2 | 3199 | 214457_at | -0.0702 | 0.0258 | |
| GSE26886 | HOXA2 | 3199 | 214457_at | -0.6190 | 0.0000 | |
| GSE29001 | HOXA2 | 3199 | 214457_at | -0.3775 | 0.1788 | |
| GSE38129 | HOXA2 | 3199 | 214457_at | -0.5433 | 0.0001 | |
| GSE45670 | HOXA2 | 3199 | 214457_at | -1.0170 | 0.0000 | |
| GSE53622 | HOXA2 | 3199 | 129853 | -0.6420 | 0.0000 | |
| GSE53624 | HOXA2 | 3199 | 129853 | -0.6975 | 0.0000 | |
| GSE63941 | HOXA2 | 3199 | 214457_at | -0.7628 | 0.0708 | |
| GSE77861 | HOXA2 | 3199 | 214457_at | -0.4269 | 0.0071 | |
| GSE97050 | HOXA2 | 3199 | A_24_P200854 | -0.8524 | 0.1908 | |
| SRP064894 | HOXA2 | 3199 | RNAseq | -0.5212 | 0.0383 | |
| SRP133303 | HOXA2 | 3199 | RNAseq | -0.7587 | 0.0397 | |
| SRP159526 | HOXA2 | 3199 | RNAseq | -0.9465 | 0.0086 | |
| SRP193095 | HOXA2 | 3199 | RNAseq | -1.4885 | 0.0000 | |
| SRP219564 | HOXA2 | 3199 | RNAseq | -0.9358 | 0.0565 | |
| TCGA | HOXA2 | 3199 | RNAseq | -0.0451 | 0.8513 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by HOXA2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HOXA2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HOXA2 | 3199 | 16 | 1 | 13 | |
| GSE20123 | HOXA2 | 3199 | 16 | 1 | 13 | |
| GSE43470 | HOXA2 | 3199 | 4 | 0 | 39 | |
| GSE46452 | HOXA2 | 3199 | 10 | 2 | 47 | |
| GSE47630 | HOXA2 | 3199 | 8 | 1 | 31 | |
| GSE54993 | HOXA2 | 3199 | 0 | 6 | 64 | |
| GSE54994 | HOXA2 | 3199 | 21 | 2 | 30 | |
| GSE60625 | HOXA2 | 3199 | 0 | 0 | 11 | |
| GSE74703 | HOXA2 | 3199 | 4 | 0 | 32 | |
| GSE74704 | HOXA2 | 3199 | 10 | 1 | 9 | |
| TCGA | HOXA2 | 3199 | 54 | 7 | 35 |
Total number of gains: 143; Total number of losses: 21; Total Number of normals: 324.
Somatic mutations of HOXA2:
Generating mutation plots.
Highly correlated genes for HOXA2:
Showing top 20/1149 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HOXA2 | FBXO10 | 0.74493 | 3 | 0 | 3 |
| HOXA2 | RNASE4 | 0.726292 | 4 | 0 | 3 |
| HOXA2 | ANO5 | 0.721348 | 4 | 0 | 3 |
| HOXA2 | CHADL | 0.71188 | 3 | 0 | 3 |
| HOXA2 | AK9 | 0.71032 | 5 | 0 | 4 |
| HOXA2 | SUCLG1 | 0.706474 | 3 | 0 | 3 |
| HOXA2 | FIBIN | 0.70597 | 4 | 0 | 4 |
| HOXA2 | FAM83D | 0.701024 | 4 | 0 | 4 |
| HOXA2 | MLYCD | 0.699777 | 3 | 0 | 3 |
| HOXA2 | ZNF585B | 0.697548 | 4 | 0 | 4 |
| HOXA2 | SLCO2B1 | 0.69706 | 3 | 0 | 3 |
| HOXA2 | TIRAP | 0.693259 | 4 | 0 | 4 |
| HOXA2 | TIFA | 0.692799 | 4 | 0 | 4 |
| HOXA2 | KLHDC8B | 0.683631 | 5 | 0 | 4 |
| HOXA2 | KCNN3 | 0.68283 | 4 | 0 | 4 |
| HOXA2 | LYRM7 | 0.682229 | 4 | 0 | 3 |
| HOXA2 | KIF1B | 0.678267 | 4 | 0 | 4 |
| HOXA2 | VMAC | 0.677063 | 3 | 0 | 3 |
| HOXA2 | ADAMTS5 | 0.677055 | 5 | 0 | 4 |
| HOXA2 | SNORA68 | 0.67439 | 4 | 0 | 4 |
For details and further investigation, click here
