| Full name: kinesin family member 1B | Alias Symbol: KIAA0591|KLP|HMSNII | ||
| Type: protein-coding gene | Cytoband: 1p36.22 | ||
| Entrez ID: 23095 | HGNC ID: HGNC:16636 | Ensembl Gene: ENSG00000054523 | OMIM ID: 605995 |
| Drug and gene relationship at DGIdb | |||
Expression of KIF1B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KIF1B | 23095 | 225878_at | -0.5745 | 0.2423 | |
| GSE20347 | KIF1B | 23095 | 209234_at | -0.6563 | 0.0009 | |
| GSE23400 | KIF1B | 23095 | 209234_at | -0.4527 | 0.0000 | |
| GSE26886 | KIF1B | 23095 | 225878_at | -1.2643 | 0.0001 | |
| GSE29001 | KIF1B | 23095 | 209234_at | -0.8591 | 0.0014 | |
| GSE38129 | KIF1B | 23095 | 209234_at | -0.6091 | 0.0005 | |
| GSE45670 | KIF1B | 23095 | 225878_at | -0.0921 | 0.5132 | |
| GSE53622 | KIF1B | 23095 | 13930 | -0.3884 | 0.0001 | |
| GSE53624 | KIF1B | 23095 | 91965 | -0.5339 | 0.0000 | |
| GSE63941 | KIF1B | 23095 | 225878_at | -0.8804 | 0.1922 | |
| GSE77861 | KIF1B | 23095 | 225878_at | -0.8812 | 0.0314 | |
| GSE97050 | KIF1B | 23095 | A_33_P3230723 | -0.5268 | 0.1203 | |
| SRP007169 | KIF1B | 23095 | RNAseq | -1.0764 | 0.0047 | |
| SRP008496 | KIF1B | 23095 | RNAseq | -0.7387 | 0.0039 | |
| SRP064894 | KIF1B | 23095 | RNAseq | -0.9033 | 0.0001 | |
| SRP133303 | KIF1B | 23095 | RNAseq | -0.4048 | 0.0111 | |
| SRP159526 | KIF1B | 23095 | RNAseq | -0.6177 | 0.0177 | |
| SRP193095 | KIF1B | 23095 | RNAseq | -0.2225 | 0.1202 | |
| SRP219564 | KIF1B | 23095 | RNAseq | -0.9507 | 0.0025 | |
| TCGA | KIF1B | 23095 | RNAseq | -0.0925 | 0.0625 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by KIF1B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KIF1B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KIF1B | 23095 | 0 | 5 | 25 | |
| GSE20123 | KIF1B | 23095 | 0 | 3 | 27 | |
| GSE43470 | KIF1B | 23095 | 6 | 5 | 32 | |
| GSE46452 | KIF1B | 23095 | 7 | 1 | 51 | |
| GSE47630 | KIF1B | 23095 | 8 | 4 | 28 | |
| GSE54993 | KIF1B | 23095 | 3 | 1 | 66 | |
| GSE54994 | KIF1B | 23095 | 11 | 4 | 38 | |
| GSE60625 | KIF1B | 23095 | 0 | 0 | 11 | |
| GSE74703 | KIF1B | 23095 | 5 | 3 | 28 | |
| GSE74704 | KIF1B | 23095 | 0 | 0 | 20 | |
| TCGA | KIF1B | 23095 | 10 | 24 | 62 |
Total number of gains: 50; Total number of losses: 50; Total Number of normals: 388.
Somatic mutations of KIF1B:
Generating mutation plots.
Highly correlated genes for KIF1B:
Showing top 20/864 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KIF1B | CNOT4 | 0.749997 | 3 | 0 | 3 |
| KIF1B | RHBDD1 | 0.746345 | 3 | 0 | 3 |
| KIF1B | SDHD | 0.743694 | 3 | 0 | 3 |
| KIF1B | PNPLA8 | 0.730858 | 3 | 0 | 3 |
| KIF1B | PINK1 | 0.725054 | 9 | 0 | 9 |
| KIF1B | CLK1 | 0.72261 | 3 | 0 | 3 |
| KIF1B | APOB | 0.718834 | 4 | 0 | 4 |
| KIF1B | PPM1L | 0.717396 | 3 | 0 | 3 |
| KIF1B | ETFA | 0.71724 | 3 | 0 | 3 |
| KIF1B | SENP8 | 0.714345 | 3 | 0 | 3 |
| KIF1B | TMEM114 | 0.709945 | 3 | 0 | 3 |
| KIF1B | PHKB | 0.696106 | 3 | 0 | 3 |
| KIF1B | SLC25A27 | 0.687941 | 3 | 0 | 3 |
| KIF1B | HOXA2 | 0.678267 | 4 | 0 | 4 |
| KIF1B | SRRM1 | 0.677921 | 3 | 0 | 3 |
| KIF1B | ICA1L | 0.676622 | 4 | 0 | 3 |
| KIF1B | ZRANB1 | 0.671717 | 4 | 0 | 4 |
| KIF1B | CHL1 | 0.67167 | 4 | 0 | 3 |
| KIF1B | WDR13 | 0.671573 | 3 | 0 | 3 |
| KIF1B | PTGR1 | 0.668986 | 4 | 0 | 3 |
For details and further investigation, click here
