| Full name: homeobox B4 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 17q21.32 | ||
| Entrez ID: 3214 | HGNC ID: HGNC:5115 | Ensembl Gene: ENSG00000182742 | OMIM ID: 142965 |
| Drug and gene relationship at DGIdb | |||
Expression of HOXB4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HOXB4 | 3214 | 231767_at | -0.1612 | 0.7894 | |
| GSE26886 | HOXB4 | 3214 | 231767_at | -0.0169 | 0.9491 | |
| GSE45670 | HOXB4 | 3214 | 231767_at | -0.0899 | 0.5604 | |
| GSE53622 | HOXB4 | 3214 | 114670 | -0.2066 | 0.1500 | |
| GSE53624 | HOXB4 | 3214 | 114670 | -0.0383 | 0.7432 | |
| GSE63941 | HOXB4 | 3214 | 231767_at | -0.6333 | 0.0894 | |
| GSE77861 | HOXB4 | 3214 | 231767_at | 0.1389 | 0.3536 | |
| GSE97050 | HOXB4 | 3214 | A_24_P416370 | -0.6759 | 0.1816 | |
| SRP064894 | HOXB4 | 3214 | RNAseq | 0.1650 | 0.6419 | |
| SRP133303 | HOXB4 | 3214 | RNAseq | -0.2985 | 0.1877 | |
| SRP159526 | HOXB4 | 3214 | RNAseq | 0.5239 | 0.1676 | |
| SRP193095 | HOXB4 | 3214 | RNAseq | -0.0532 | 0.8255 | |
| SRP219564 | HOXB4 | 3214 | RNAseq | -0.3080 | 0.4720 | |
| TCGA | HOXB4 | 3214 | RNAseq | 0.1512 | 0.3489 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by HOXB4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HOXB4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HOXB4 | 3214 | 5 | 2 | 23 | |
| GSE20123 | HOXB4 | 3214 | 5 | 2 | 23 | |
| GSE43470 | HOXB4 | 3214 | 3 | 1 | 39 | |
| GSE46452 | HOXB4 | 3214 | 32 | 0 | 27 | |
| GSE47630 | HOXB4 | 3214 | 9 | 0 | 31 | |
| GSE54993 | HOXB4 | 3214 | 2 | 4 | 64 | |
| GSE54994 | HOXB4 | 3214 | 10 | 6 | 37 | |
| GSE60625 | HOXB4 | 3214 | 4 | 0 | 7 | |
| GSE74703 | HOXB4 | 3214 | 3 | 1 | 32 | |
| GSE74704 | HOXB4 | 3214 | 4 | 1 | 15 | |
| TCGA | HOXB4 | 3214 | 27 | 6 | 63 |
Total number of gains: 104; Total number of losses: 23; Total Number of normals: 361.
Somatic mutations of HOXB4:
Generating mutation plots.
Highly correlated genes for HOXB4:
Showing top 20/31 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HOXB4 | DYNLL2 | 0.739087 | 3 | 0 | 3 |
| HOXB4 | OAZ2 | 0.722936 | 3 | 0 | 3 |
| HOXB4 | TLE2 | 0.698362 | 3 | 0 | 3 |
| HOXB4 | TRPM6 | 0.692535 | 3 | 0 | 3 |
| HOXB4 | EMD | 0.685269 | 3 | 0 | 3 |
| HOXB4 | APBA1 | 0.68468 | 4 | 0 | 3 |
| HOXB4 | SNF8 | 0.677749 | 3 | 0 | 3 |
| HOXB4 | GSTM2 | 0.673489 | 3 | 0 | 3 |
| HOXB4 | GSTM3 | 0.659861 | 3 | 0 | 3 |
| HOXB4 | CRYBA1 | 0.653236 | 3 | 0 | 3 |
| HOXB4 | PRPH2 | 0.644662 | 3 | 0 | 3 |
| HOXB4 | VPS39 | 0.64359 | 4 | 0 | 3 |
| HOXB4 | HOXB3 | 0.635322 | 8 | 0 | 6 |
| HOXB4 | YPEL2 | 0.635185 | 3 | 0 | 3 |
| HOXB4 | CCDC65 | 0.632056 | 3 | 0 | 3 |
| HOXB4 | NFATC1 | 0.628588 | 3 | 0 | 3 |
| HOXB4 | MLX | 0.615855 | 3 | 0 | 3 |
| HOXB4 | CBX1 | 0.607143 | 3 | 0 | 3 |
| HOXB4 | GPR31 | 0.601538 | 3 | 0 | 3 |
| HOXB4 | KIF13A | 0.597748 | 3 | 0 | 3 |
For details and further investigation, click here
