| Full name: glutathione S-transferase mu 3 | Alias Symbol: GST5 | ||
| Type: protein-coding gene | Cytoband: 1p13.3 | ||
| Entrez ID: 2947 | HGNC ID: HGNC:4635 | Ensembl Gene: ENSG00000134202 | OMIM ID: 138390 |
| Drug and gene relationship at DGIdb | |||
Expression of GSTM3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GSTM3 | 2947 | 202554_s_at | 0.3007 | 0.8303 | |
| GSE20347 | GSTM3 | 2947 | 202554_s_at | -0.0472 | 0.9549 | |
| GSE23400 | GSTM3 | 2947 | 202554_s_at | 0.6361 | 0.0281 | |
| GSE26886 | GSTM3 | 2947 | 202554_s_at | -0.3649 | 0.7196 | |
| GSE29001 | GSTM3 | 2947 | 202554_s_at | 0.4392 | 0.6150 | |
| GSE38129 | GSTM3 | 2947 | 202554_s_at | 0.4265 | 0.4113 | |
| GSE45670 | GSTM3 | 2947 | 202554_s_at | 0.1615 | 0.8558 | |
| GSE53622 | GSTM3 | 2947 | 127416 | -1.0959 | 0.0000 | |
| GSE53624 | GSTM3 | 2947 | 127416 | -0.7537 | 0.0005 | |
| GSE63941 | GSTM3 | 2947 | 202554_s_at | -1.9073 | 0.3825 | |
| GSE77861 | GSTM3 | 2947 | 202554_s_at | 0.4214 | 0.6267 | |
| GSE97050 | GSTM3 | 2947 | A_23_P12343 | -0.7052 | 0.1887 | |
| SRP007169 | GSTM3 | 2947 | RNAseq | 1.9654 | 0.0023 | |
| SRP008496 | GSTM3 | 2947 | RNAseq | 1.6742 | 0.0010 | |
| SRP064894 | GSTM3 | 2947 | RNAseq | -0.2896 | 0.3523 | |
| SRP133303 | GSTM3 | 2947 | RNAseq | -0.2869 | 0.2402 | |
| SRP159526 | GSTM3 | 2947 | RNAseq | 2.7330 | 0.0003 | |
| SRP193095 | GSTM3 | 2947 | RNAseq | 1.0102 | 0.0070 | |
| SRP219564 | GSTM3 | 2947 | RNAseq | -0.4585 | 0.5278 | |
| TCGA | GSTM3 | 2947 | RNAseq | -0.2620 | 0.2776 |
Upregulated datasets: 4; Downregulated datasets: 1.
Survival by GSTM3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GSTM3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GSTM3 | 2947 | 0 | 12 | 18 | |
| GSE20123 | GSTM3 | 2947 | 0 | 11 | 19 | |
| GSE43470 | GSTM3 | 2947 | 0 | 9 | 34 | |
| GSE46452 | GSTM3 | 2947 | 2 | 1 | 56 | |
| GSE47630 | GSTM3 | 2947 | 9 | 5 | 26 | |
| GSE54993 | GSTM3 | 2947 | 0 | 1 | 69 | |
| GSE54994 | GSTM3 | 2947 | 7 | 4 | 42 | |
| GSE60625 | GSTM3 | 2947 | 0 | 0 | 11 | |
| GSE74703 | GSTM3 | 2947 | 0 | 7 | 29 | |
| GSE74704 | GSTM3 | 2947 | 0 | 7 | 13 | |
| TCGA | GSTM3 | 2947 | 9 | 26 | 61 |
Total number of gains: 27; Total number of losses: 83; Total Number of normals: 378.
Somatic mutations of GSTM3:
Generating mutation plots.
Highly correlated genes for GSTM3:
Showing top 20/97 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GSTM3 | ATP6V1E1 | 0.709203 | 3 | 0 | 3 |
| GSTM3 | GSTM2 | 0.692392 | 12 | 0 | 12 |
| GSTM3 | MRPL35 | 0.661755 | 3 | 0 | 3 |
| GSTM3 | HOXB4 | 0.659861 | 3 | 0 | 3 |
| GSTM3 | GSTM1 | 0.65141 | 12 | 0 | 11 |
| GSTM3 | VWA5A | 0.642727 | 3 | 0 | 3 |
| GSTM3 | AKR1C1 | 0.634261 | 10 | 0 | 10 |
| GSTM3 | SLC9A6 | 0.626155 | 4 | 0 | 3 |
| GSTM3 | SAE1 | 0.61888 | 3 | 0 | 3 |
| GSTM3 | UBE2Q2 | 0.615462 | 3 | 0 | 3 |
| GSTM3 | AKR1C2 | 0.612326 | 10 | 0 | 9 |
| GSTM3 | TCEAL1 | 0.61026 | 5 | 0 | 4 |
| GSTM3 | TSPAN7 | 0.605646 | 12 | 0 | 11 |
| GSTM3 | QRFPR | 0.604117 | 3 | 0 | 3 |
| GSTM3 | CDNF | 0.601975 | 3 | 0 | 3 |
| GSTM3 | PRUNE2 | 0.601605 | 3 | 0 | 3 |
| GSTM3 | AKR1C3 | 0.597932 | 12 | 0 | 9 |
| GSTM3 | PSMC3 | 0.596074 | 3 | 0 | 3 |
| GSTM3 | EIF3F | 0.593408 | 4 | 0 | 3 |
| GSTM3 | TMEM165 | 0.589925 | 3 | 0 | 3 |
For details and further investigation, click here
