| Full name: homeobox B3 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 17q21.32 | ||
| Entrez ID: 3213 | HGNC ID: HGNC:5114 | Ensembl Gene: ENSG00000120093 | OMIM ID: 142966 |
| Drug and gene relationship at DGIdb | |||
Expression of HOXB3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HOXB3 | 3213 | 228904_at | -0.5731 | 0.4781 | |
| GSE20347 | HOXB3 | 3213 | 208414_s_at | -0.0781 | 0.3499 | |
| GSE23400 | HOXB3 | 3213 | 208414_s_at | -0.0503 | 0.0803 | |
| GSE26886 | HOXB3 | 3213 | 228904_at | -0.2156 | 0.7173 | |
| GSE29001 | HOXB3 | 3213 | 208414_s_at | -0.2209 | 0.0528 | |
| GSE38129 | HOXB3 | 3213 | 208414_s_at | -0.1047 | 0.1133 | |
| GSE45670 | HOXB3 | 3213 | 228904_at | -0.6352 | 0.1182 | |
| GSE53622 | HOXB3 | 3213 | 145004 | 0.4224 | 0.0005 | |
| GSE53624 | HOXB3 | 3213 | 145004 | 0.2328 | 0.0371 | |
| GSE63941 | HOXB3 | 3213 | 228904_at | -2.1903 | 0.0534 | |
| GSE77861 | HOXB3 | 3213 | 228904_at | 0.0607 | 0.9151 | |
| GSE97050 | HOXB3 | 3213 | A_23_P316511 | -0.3979 | 0.1711 | |
| SRP064894 | HOXB3 | 3213 | RNAseq | 0.3360 | 0.1998 | |
| SRP133303 | HOXB3 | 3213 | RNAseq | -0.1186 | 0.6030 | |
| SRP159526 | HOXB3 | 3213 | RNAseq | 0.6236 | 0.0863 | |
| SRP193095 | HOXB3 | 3213 | RNAseq | -0.0405 | 0.8417 | |
| SRP219564 | HOXB3 | 3213 | RNAseq | -0.4559 | 0.2389 | |
| TCGA | HOXB3 | 3213 | RNAseq | 0.2092 | 0.1019 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by HOXB3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HOXB3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HOXB3 | 3213 | 5 | 2 | 23 | |
| GSE20123 | HOXB3 | 3213 | 5 | 2 | 23 | |
| GSE43470 | HOXB3 | 3213 | 3 | 1 | 39 | |
| GSE46452 | HOXB3 | 3213 | 32 | 0 | 27 | |
| GSE47630 | HOXB3 | 3213 | 9 | 0 | 31 | |
| GSE54993 | HOXB3 | 3213 | 2 | 4 | 64 | |
| GSE54994 | HOXB3 | 3213 | 10 | 6 | 37 | |
| GSE60625 | HOXB3 | 3213 | 4 | 0 | 7 | |
| GSE74703 | HOXB3 | 3213 | 3 | 1 | 32 | |
| GSE74704 | HOXB3 | 3213 | 4 | 1 | 15 | |
| TCGA | HOXB3 | 3213 | 27 | 6 | 63 |
Total number of gains: 104; Total number of losses: 23; Total Number of normals: 361.
Somatic mutations of HOXB3:
Generating mutation plots.
Highly correlated genes for HOXB3:
Showing top 20/274 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HOXB3 | FUNDC2 | 0.772279 | 3 | 0 | 3 |
| HOXB3 | CNR1 | 0.757787 | 3 | 0 | 3 |
| HOXB3 | DCHS1 | 0.713684 | 3 | 0 | 3 |
| HOXB3 | CHST8 | 0.713343 | 3 | 0 | 3 |
| HOXB3 | CAV3 | 0.707598 | 3 | 0 | 3 |
| HOXB3 | OXR1 | 0.691517 | 3 | 0 | 3 |
| HOXB3 | ABCC9 | 0.689448 | 3 | 0 | 3 |
| HOXB3 | CKMT2 | 0.684251 | 3 | 0 | 3 |
| HOXB3 | JPH2 | 0.671211 | 3 | 0 | 3 |
| HOXB3 | HOXB2 | 0.671095 | 10 | 0 | 9 |
| HOXB3 | HIPK1 | 0.671058 | 4 | 0 | 3 |
| HOXB3 | GBGT1 | 0.669941 | 3 | 0 | 3 |
| HOXB3 | EDNRB | 0.669699 | 3 | 0 | 3 |
| HOXB3 | N4BP2L1 | 0.668787 | 3 | 0 | 3 |
| HOXB3 | LPAR1 | 0.667348 | 4 | 0 | 3 |
| HOXB3 | PTH1R | 0.664334 | 4 | 0 | 3 |
| HOXB3 | PRELP | 0.664104 | 3 | 0 | 3 |
| HOXB3 | SNX19 | 0.663425 | 3 | 0 | 3 |
| HOXB3 | SIRT2 | 0.662667 | 3 | 0 | 3 |
| HOXB3 | LDOC1 | 0.661598 | 4 | 0 | 4 |
For details and further investigation, click here
