| Full name: heat shock protein family A (Hsp70) member 14 | Alias Symbol: HSP70-4|HSP70L1 | ||
| Type: protein-coding gene | Cytoband: 10p13 | ||
| Entrez ID: 51182 | HGNC ID: HGNC:29526 | Ensembl Gene: ENSG00000187522 | OMIM ID: 610369 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of HSPA14:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HSPA14 | 51182 | 219212_at | 0.4341 | 0.3893 | |
| GSE20347 | HSPA14 | 51182 | 219212_at | 0.4341 | 0.0170 | |
| GSE23400 | HSPA14 | 51182 | 219212_at | 0.3577 | 0.0002 | |
| GSE26886 | HSPA14 | 51182 | 219212_at | -0.1874 | 0.5654 | |
| GSE29001 | HSPA14 | 51182 | 219212_at | 0.4646 | 0.0627 | |
| GSE38129 | HSPA14 | 51182 | 219212_at | 0.5546 | 0.0001 | |
| GSE45670 | HSPA14 | 51182 | 219212_at | 0.0850 | 0.6117 | |
| GSE53622 | HSPA14 | 51182 | 61523 | 0.0736 | 0.2608 | |
| GSE53624 | HSPA14 | 51182 | 61523 | 0.3155 | 0.0000 | |
| GSE63941 | HSPA14 | 51182 | 219212_at | 0.0999 | 0.8493 | |
| GSE77861 | HSPA14 | 51182 | 219212_at | 0.0444 | 0.8869 | |
| GSE97050 | HSPA14 | 51182 | A_23_P63829 | 0.5722 | 0.1184 | |
| SRP007169 | HSPA14 | 51182 | RNAseq | -0.0231 | 0.9509 | |
| SRP008496 | HSPA14 | 51182 | RNAseq | 0.0959 | 0.6312 | |
| SRP064894 | HSPA14 | 51182 | RNAseq | -0.0247 | 0.8653 | |
| SRP133303 | HSPA14 | 51182 | RNAseq | 0.0886 | 0.5709 | |
| SRP159526 | HSPA14 | 51182 | RNAseq | -0.2204 | 0.4975 | |
| SRP193095 | HSPA14 | 51182 | RNAseq | -0.0809 | 0.4610 | |
| SRP219564 | HSPA14 | 51182 | RNAseq | -0.3189 | 0.2187 | |
| TCGA | HSPA14 | 51182 | RNAseq | 0.1413 | 0.0121 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by HSPA14 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HSPA14:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HSPA14 | 51182 | 3 | 8 | 19 | |
| GSE20123 | HSPA14 | 51182 | 3 | 7 | 20 | |
| GSE43470 | HSPA14 | 51182 | 3 | 5 | 35 | |
| GSE46452 | HSPA14 | 51182 | 1 | 14 | 44 | |
| GSE47630 | HSPA14 | 51182 | 5 | 15 | 20 | |
| GSE54993 | HSPA14 | 51182 | 10 | 0 | 60 | |
| GSE54994 | HSPA14 | 51182 | 4 | 9 | 40 | |
| GSE60625 | HSPA14 | 51182 | 0 | 0 | 11 | |
| GSE74703 | HSPA14 | 51182 | 2 | 3 | 31 | |
| GSE74704 | HSPA14 | 51182 | 0 | 6 | 14 | |
| TCGA | HSPA14 | 51182 | 20 | 25 | 51 |
Total number of gains: 51; Total number of losses: 92; Total Number of normals: 345.
Somatic mutations of HSPA14:
Generating mutation plots.
Highly correlated genes for HSPA14:
Showing top 20/504 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HSPA14 | PSEN1 | 0.75492 | 3 | 0 | 3 |
| HSPA14 | FAM118B | 0.734299 | 3 | 0 | 3 |
| HSPA14 | INTS12 | 0.715959 | 3 | 0 | 3 |
| HSPA14 | NEK4 | 0.70498 | 3 | 0 | 3 |
| HSPA14 | RBM39 | 0.685642 | 3 | 0 | 3 |
| HSPA14 | SASS6 | 0.681064 | 3 | 0 | 3 |
| HSPA14 | OSTC | 0.678969 | 4 | 0 | 3 |
| HSPA14 | ZNF35 | 0.674811 | 3 | 0 | 3 |
| HSPA14 | DRAM2 | 0.670131 | 3 | 0 | 3 |
| HSPA14 | TBC1D15 | 0.669212 | 3 | 0 | 3 |
| HSPA14 | ZBTB44 | 0.667097 | 3 | 0 | 3 |
| HSPA14 | LIPA | 0.665 | 4 | 0 | 3 |
| HSPA14 | CDC123 | 0.662092 | 12 | 0 | 11 |
| HSPA14 | B3GNT7 | 0.66009 | 3 | 0 | 3 |
| HSPA14 | NUDT5 | 0.659874 | 8 | 0 | 8 |
| HSPA14 | DUSP7 | 0.659155 | 3 | 0 | 3 |
| HSPA14 | ZNF200 | 0.658726 | 3 | 0 | 3 |
| HSPA14 | HERC4 | 0.655823 | 3 | 0 | 3 |
| HSPA14 | SRP72 | 0.655688 | 4 | 0 | 3 |
| HSPA14 | SUB1 | 0.652744 | 3 | 0 | 3 |
For details and further investigation, click here
