| Full name: signal recognition particle 72 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 4q12 | ||
| Entrez ID: 6731 | HGNC ID: HGNC:11303 | Ensembl Gene: ENSG00000174780 | OMIM ID: 602122 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of SRP72:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SRP72 | 6731 | 208801_at | 0.1214 | 0.7553 | |
| GSE20347 | SRP72 | 6731 | 208801_at | -0.2214 | 0.0634 | |
| GSE23400 | SRP72 | 6731 | 208801_at | 0.2118 | 0.0065 | |
| GSE26886 | SRP72 | 6731 | 208801_at | -0.0951 | 0.6328 | |
| GSE29001 | SRP72 | 6731 | 208801_at | 0.0452 | 0.8655 | |
| GSE38129 | SRP72 | 6731 | 208801_at | 0.1211 | 0.4400 | |
| GSE45670 | SRP72 | 6731 | 208801_at | 0.0325 | 0.9160 | |
| GSE53622 | SRP72 | 6731 | 57903 | 0.2197 | 0.0000 | |
| GSE53624 | SRP72 | 6731 | 57903 | 0.2620 | 0.0004 | |
| GSE63941 | SRP72 | 6731 | 208801_at | -0.2799 | 0.5294 | |
| GSE77861 | SRP72 | 6731 | 208801_at | -0.1055 | 0.7322 | |
| GSE97050 | SRP72 | 6731 | A_23_P337201 | 0.3215 | 0.1698 | |
| SRP007169 | SRP72 | 6731 | RNAseq | -0.2480 | 0.5733 | |
| SRP008496 | SRP72 | 6731 | RNAseq | -0.1356 | 0.5529 | |
| SRP064894 | SRP72 | 6731 | RNAseq | 0.0511 | 0.7393 | |
| SRP133303 | SRP72 | 6731 | RNAseq | 0.3653 | 0.0287 | |
| SRP159526 | SRP72 | 6731 | RNAseq | -0.2985 | 0.1112 | |
| SRP193095 | SRP72 | 6731 | RNAseq | -0.2651 | 0.0083 | |
| SRP219564 | SRP72 | 6731 | RNAseq | -0.1863 | 0.5544 | |
| TCGA | SRP72 | 6731 | RNAseq | 0.0387 | 0.3613 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SRP72 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SRP72:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SRP72 | 6731 | 3 | 12 | 15 | |
| GSE20123 | SRP72 | 6731 | 2 | 12 | 16 | |
| GSE43470 | SRP72 | 6731 | 0 | 14 | 29 | |
| GSE46452 | SRP72 | 6731 | 1 | 36 | 22 | |
| GSE47630 | SRP72 | 6731 | 0 | 19 | 21 | |
| GSE54993 | SRP72 | 6731 | 7 | 0 | 63 | |
| GSE54994 | SRP72 | 6731 | 2 | 10 | 41 | |
| GSE60625 | SRP72 | 6731 | 0 | 0 | 11 | |
| GSE74703 | SRP72 | 6731 | 0 | 12 | 24 | |
| GSE74704 | SRP72 | 6731 | 1 | 7 | 12 | |
| TCGA | SRP72 | 6731 | 21 | 26 | 49 |
Total number of gains: 37; Total number of losses: 148; Total Number of normals: 303.
Somatic mutations of SRP72:
Generating mutation plots.
Highly correlated genes for SRP72:
Showing top 20/397 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SRP72 | MDM2 | 0.724421 | 3 | 0 | 3 |
| SRP72 | MILR1 | 0.7207 | 3 | 0 | 3 |
| SRP72 | SPATA9 | 0.718654 | 3 | 0 | 3 |
| SRP72 | MITD1 | 0.713102 | 4 | 0 | 3 |
| SRP72 | TET2 | 0.71254 | 3 | 0 | 3 |
| SRP72 | POLR2B | 0.708464 | 10 | 0 | 9 |
| SRP72 | BPNT1 | 0.703749 | 3 | 0 | 3 |
| SRP72 | OGFOD1 | 0.703377 | 3 | 0 | 3 |
| SRP72 | ANKRD28 | 0.701644 | 3 | 0 | 3 |
| SRP72 | PIK3CB | 0.700282 | 3 | 0 | 3 |
| SRP72 | LACTB | 0.699228 | 4 | 0 | 3 |
| SRP72 | BTF3L4 | 0.698081 | 3 | 0 | 3 |
| SRP72 | FIP1L1 | 0.696184 | 6 | 0 | 5 |
| SRP72 | SLC10A7 | 0.693446 | 4 | 0 | 4 |
| SRP72 | IRAK2 | 0.692485 | 3 | 0 | 3 |
| SRP72 | AIMP2 | 0.688559 | 3 | 0 | 3 |
| SRP72 | CCNH | 0.675568 | 4 | 0 | 3 |
| SRP72 | ARPC3 | 0.674835 | 3 | 0 | 3 |
| SRP72 | SUB1 | 0.67357 | 6 | 0 | 4 |
| SRP72 | NDUFS4 | 0.67334 | 4 | 0 | 3 |
For details and further investigation, click here
