PRPF38B

 

Full name: pre-mRNA processing factor 38B Alias Symbol: FLJ10330|NET1
Type: protein-coding gene Cytoband: 1p13.3
Entrez ID: 55119 HGNC ID: HGNC:25512 Ensembl Gene: ENSG00000134186 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of PRPF38B:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 PRPF38B 55119 218040_at -0.0409 0.8879
GSE20347 PRPF38B 55119 218040_at -0.2215 0.0394
GSE23400 PRPF38B 55119 218040_at -0.0429 0.4116
GSE26886 PRPF38B 55119 218040_at -0.7061 0.0004
GSE29001 PRPF38B 55119 218040_at 0.1426 0.3076
GSE38129 PRPF38B 55119 218040_at -0.0797 0.4219
GSE45670 PRPF38B 55119 218040_at 0.0237 0.8789
GSE53622 PRPF38B 55119 122825 0.1987 0.0001
GSE53624 PRPF38B 55119 122825 0.2253 0.0001
GSE63941 PRPF38B 55119 218040_at -0.2597 0.5768
GSE77861 PRPF38B 55119 218040_at -0.2192 0.3093
GSE97050 PRPF38B 55119 A_33_P3329834 0.2803 0.3891
SRP007169 PRPF38B 55119 RNAseq 1.0077 0.0185
SRP008496 PRPF38B 55119 RNAseq 1.0372 0.0016
SRP064894 PRPF38B 55119 RNAseq 0.1838 0.3695
SRP133303 PRPF38B 55119 RNAseq 0.0500 0.6444
SRP159526 PRPF38B 55119 RNAseq -0.4120 0.1169
SRP193095 PRPF38B 55119 RNAseq -0.0588 0.6139
SRP219564 PRPF38B 55119 RNAseq -0.1315 0.6485
TCGA PRPF38B 55119 RNAseq -0.0839 0.0843

Upregulated datasets: 2; Downregulated datasets: 0.  


 

Survival by PRPF38B expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of PRPF38B:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 PRPF38B 55119 0 12 18
GSE20123 PRPF38B 55119 0 11 19
GSE43470 PRPF38B 55119 0 8 35
GSE46452 PRPF38B 55119 2 1 56
GSE47630 PRPF38B 55119 9 5 26
GSE54993 PRPF38B 55119 0 1 69
GSE54994 PRPF38B 55119 7 4 42
GSE60625 PRPF38B 55119 0 0 11
GSE74703 PRPF38B 55119 0 6 30
GSE74704 PRPF38B 55119 0 7 13
TCGA PRPF38B 55119 8 26 62

Total number of gains: 26; Total number of losses: 81; Total Number of normals: 381.  


 

Somatic mutations of PRPF38B:

 

Generating mutation plots.

 

Highly correlated genes for PRPF38B:

 

Showing top 20/273 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
PRPF38BCUL20.78592303
PRPF38BUBE3C0.78122303
PRPF38BJAK20.751403303
PRPF38BPRADC10.722639303
PRPF38BPSMC60.717561303
PRPF38BIDI10.715761303
PRPF38BCRK0.702331303
PRPF38BGTF3C60.701947303
PRPF38BRBM70.696315404
PRPF38BMAT2B0.695712303
PRPF38BSGMS20.689172404
PRPF38BKCTD150.688671303
PRPF38BALAS10.682455303
PRPF38BGOT10.680263303
PRPF38BEPG50.680196303
PRPF38BZNF4360.678737303
PRPF38BNTAN10.67676303
PRPF38BSTXBP50.671002303
PRPF38BREEP30.670906403
PRPF38BPHKB0.666533303

For details and further investigation, click here