| Full name: SEC24 homolog B, COPII coat complex component | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 4q25 | ||
| Entrez ID: 10427 | HGNC ID: HGNC:10704 | Ensembl Gene: ENSG00000138802 | OMIM ID: 607184 |
| Drug and gene relationship at DGIdb | |||
Expression of SEC24B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SEC24B | 10427 | 202798_at | -0.2738 | 0.4154 | |
| GSE20347 | SEC24B | 10427 | 202798_at | -0.5395 | 0.0003 | |
| GSE23400 | SEC24B | 10427 | 202798_at | -0.2633 | 0.0013 | |
| GSE26886 | SEC24B | 10427 | 202798_at | -0.1284 | 0.6769 | |
| GSE29001 | SEC24B | 10427 | 202798_at | -0.5372 | 0.2510 | |
| GSE38129 | SEC24B | 10427 | 202798_at | -0.3999 | 0.0027 | |
| GSE45670 | SEC24B | 10427 | 202798_at | -0.4504 | 0.0002 | |
| GSE53622 | SEC24B | 10427 | 45259 | -0.4264 | 0.0000 | |
| GSE53624 | SEC24B | 10427 | 45259 | -0.6461 | 0.0000 | |
| GSE63941 | SEC24B | 10427 | 202798_at | -0.2891 | 0.2316 | |
| GSE77861 | SEC24B | 10427 | 202798_at | -0.5415 | 0.0495 | |
| GSE97050 | SEC24B | 10427 | A_23_P69683 | -0.2581 | 0.3563 | |
| SRP007169 | SEC24B | 10427 | RNAseq | -0.7514 | 0.0359 | |
| SRP008496 | SEC24B | 10427 | RNAseq | -0.6636 | 0.0007 | |
| SRP064894 | SEC24B | 10427 | RNAseq | -0.6660 | 0.0051 | |
| SRP133303 | SEC24B | 10427 | RNAseq | -0.0494 | 0.7576 | |
| SRP159526 | SEC24B | 10427 | RNAseq | -0.7081 | 0.0000 | |
| SRP193095 | SEC24B | 10427 | RNAseq | -0.4548 | 0.0000 | |
| SRP219564 | SEC24B | 10427 | RNAseq | -0.4597 | 0.0963 | |
| TCGA | SEC24B | 10427 | RNAseq | -0.0760 | 0.0947 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SEC24B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SEC24B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SEC24B | 10427 | 1 | 12 | 17 | |
| GSE20123 | SEC24B | 10427 | 1 | 12 | 17 | |
| GSE43470 | SEC24B | 10427 | 0 | 13 | 30 | |
| GSE46452 | SEC24B | 10427 | 1 | 36 | 22 | |
| GSE47630 | SEC24B | 10427 | 0 | 20 | 20 | |
| GSE54993 | SEC24B | 10427 | 9 | 0 | 61 | |
| GSE54994 | SEC24B | 10427 | 1 | 10 | 42 | |
| GSE60625 | SEC24B | 10427 | 0 | 3 | 8 | |
| GSE74703 | SEC24B | 10427 | 0 | 11 | 25 | |
| GSE74704 | SEC24B | 10427 | 0 | 6 | 14 | |
| TCGA | SEC24B | 10427 | 8 | 35 | 53 |
Total number of gains: 21; Total number of losses: 158; Total Number of normals: 309.
Somatic mutations of SEC24B:
Generating mutation plots.
Highly correlated genes for SEC24B:
Showing top 20/1203 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SEC24B | PTCD2 | 0.770326 | 3 | 0 | 3 |
| SEC24B | KDM3A | 0.763175 | 4 | 0 | 4 |
| SEC24B | UBE2D2 | 0.754498 | 3 | 0 | 3 |
| SEC24B | HSD17B12 | 0.74974 | 3 | 0 | 3 |
| SEC24B | ZMAT1 | 0.745558 | 3 | 0 | 3 |
| SEC24B | FBXO8 | 0.737239 | 8 | 0 | 8 |
| SEC24B | LCOR | 0.737104 | 3 | 0 | 3 |
| SEC24B | RBM20 | 0.734476 | 3 | 0 | 3 |
| SEC24B | EIF4E2 | 0.732885 | 3 | 0 | 3 |
| SEC24B | GPBP1 | 0.72645 | 4 | 0 | 3 |
| SEC24B | BRK1 | 0.724957 | 6 | 0 | 6 |
| SEC24B | ZRANB1 | 0.72009 | 4 | 0 | 4 |
| SEC24B | EIF3I | 0.712218 | 3 | 0 | 3 |
| SEC24B | GMPPB | 0.707124 | 3 | 0 | 3 |
| SEC24B | AK3 | 0.704479 | 7 | 0 | 7 |
| SEC24B | LAMTOR3 | 0.701464 | 12 | 0 | 10 |
| SEC24B | ARG2 | 0.701429 | 3 | 0 | 3 |
| SEC24B | SCOC | 0.696487 | 9 | 0 | 8 |
| SEC24B | APH1A | 0.693168 | 3 | 0 | 3 |
| SEC24B | TMEM106B | 0.686922 | 4 | 0 | 3 |
For details and further investigation, click here
