| Full name: tubulin beta 4A class IVa | Alias Symbol: beta-5 | ||
| Type: protein-coding gene | Cytoband: 19p13.3 | ||
| Entrez ID: 10382 | HGNC ID: HGNC:20774 | Ensembl Gene: ENSG00000104833 | OMIM ID: 602662 |
| Drug and gene relationship at DGIdb | |||
TUBB4A involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa05130 | Pathogenic Escherichia coli infection |
Expression of TUBB4A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TUBB4A | 10382 | 212664_at | 0.0488 | 0.9044 | |
| GSE20347 | TUBB4A | 10382 | 212664_at | -0.1046 | 0.3925 | |
| GSE23400 | TUBB4A | 10382 | 212664_at | -0.1790 | 0.0028 | |
| GSE26886 | TUBB4A | 10382 | 212664_at | -0.3332 | 0.0157 | |
| GSE29001 | TUBB4A | 10382 | 212664_at | -0.2719 | 0.1596 | |
| GSE38129 | TUBB4A | 10382 | 212664_at | -0.1368 | 0.2689 | |
| GSE45670 | TUBB4A | 10382 | 212664_at | 0.0790 | 0.5737 | |
| GSE53622 | TUBB4A | 10382 | 153252 | 0.3119 | 0.0712 | |
| GSE53624 | TUBB4A | 10382 | 153252 | 0.3426 | 0.0045 | |
| GSE63941 | TUBB4A | 10382 | 212664_at | 0.3243 | 0.3768 | |
| GSE77861 | TUBB4A | 10382 | 212664_at | -0.1338 | 0.3577 | |
| GSE97050 | TUBB4A | 10382 | A_23_P113656 | -0.2480 | 0.3374 | |
| SRP159526 | TUBB4A | 10382 | RNAseq | 3.3972 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by TUBB4A expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of TUBB4A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TUBB4A | 10382 | 5 | 3 | 22 | |
| GSE20123 | TUBB4A | 10382 | 4 | 2 | 24 | |
| GSE43470 | TUBB4A | 10382 | 2 | 6 | 35 | |
| GSE46452 | TUBB4A | 10382 | 47 | 1 | 11 | |
| GSE47630 | TUBB4A | 10382 | 5 | 7 | 28 | |
| GSE54993 | TUBB4A | 10382 | 16 | 3 | 51 | |
| GSE54994 | TUBB4A | 10382 | 6 | 14 | 33 | |
| GSE60625 | TUBB4A | 10382 | 9 | 0 | 2 | |
| GSE74703 | TUBB4A | 10382 | 2 | 4 | 30 | |
| GSE74704 | TUBB4A | 10382 | 1 | 2 | 17 | |
| TCGA | TUBB4A | 10382 | 9 | 19 | 68 |
Total number of gains: 106; Total number of losses: 61; Total Number of normals: 321.
Somatic mutations of TUBB4A:
Generating mutation plots.
Highly correlated genes for TUBB4A:
Showing top 20/544 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TUBB4A | STXBP6 | 0.797998 | 3 | 0 | 3 |
| TUBB4A | OR1G1 | 0.721945 | 3 | 0 | 3 |
| TUBB4A | C8A | 0.704045 | 4 | 0 | 4 |
| TUBB4A | PDE1B | 0.701809 | 3 | 0 | 3 |
| TUBB4A | RPH3A | 0.698714 | 6 | 0 | 6 |
| TUBB4A | P2RX6 | 0.698444 | 4 | 0 | 4 |
| TUBB4A | G6PC2 | 0.697429 | 5 | 0 | 5 |
| TUBB4A | GPR27 | 0.696415 | 3 | 0 | 3 |
| TUBB4A | GPR31 | 0.690871 | 4 | 0 | 4 |
| TUBB4A | KIR2DS5 | 0.690114 | 4 | 0 | 4 |
| TUBB4A | SNPH | 0.689576 | 3 | 0 | 3 |
| TUBB4A | PDYN | 0.685754 | 5 | 0 | 5 |
| TUBB4A | CHAD | 0.684046 | 4 | 0 | 4 |
| TUBB4A | GML | 0.683748 | 6 | 0 | 6 |
| TUBB4A | TCP10L | 0.682427 | 4 | 0 | 4 |
| TUBB4A | CER1 | 0.680419 | 5 | 0 | 5 |
| TUBB4A | PDK4 | 0.679593 | 3 | 0 | 3 |
| TUBB4A | TAPT1 | 0.679464 | 6 | 0 | 6 |
| TUBB4A | TAAR2 | 0.677953 | 3 | 0 | 3 |
| TUBB4A | PRL | 0.676678 | 4 | 0 | 4 |
For details and further investigation, click here
