| Full name: penta-EF-hand domain containing 1 | Alias Symbol: PEF1A | ||
| Type: protein-coding gene | Cytoband: 1p35.2 | ||
| Entrez ID: 553115 | HGNC ID: HGNC:30009 | Ensembl Gene: ENSG00000162517 | OMIM ID: 610033 |
| Drug and gene relationship at DGIdb | |||
Expression of PEF1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PEF1 | 553115 | 217923_at | 0.2109 | 0.4375 | |
| GSE20347 | PEF1 | 553115 | 217923_at | 0.0592 | 0.6297 | |
| GSE23400 | PEF1 | 553115 | 217923_at | 0.2284 | 0.0003 | |
| GSE26886 | PEF1 | 553115 | 217923_at | 0.0056 | 0.9823 | |
| GSE29001 | PEF1 | 553115 | 217923_at | 0.4182 | 0.3021 | |
| GSE38129 | PEF1 | 553115 | 217923_at | 0.1818 | 0.2117 | |
| GSE45670 | PEF1 | 553115 | 217923_at | 0.2836 | 0.0150 | |
| GSE53622 | PEF1 | 553115 | 155247 | -0.1873 | 0.0018 | |
| GSE53624 | PEF1 | 553115 | 57003 | 0.2573 | 0.0000 | |
| GSE63941 | PEF1 | 553115 | 217923_at | 0.1164 | 0.7123 | |
| GSE77861 | PEF1 | 553115 | 217923_at | 0.1123 | 0.7070 | |
| GSE97050 | PEF1 | 553115 | A_23_P313 | -0.2193 | 0.2533 | |
| SRP007169 | PEF1 | 553115 | RNAseq | -0.3757 | 0.3638 | |
| SRP008496 | PEF1 | 553115 | RNAseq | -0.5693 | 0.0090 | |
| SRP064894 | PEF1 | 553115 | RNAseq | 0.5121 | 0.0311 | |
| SRP133303 | PEF1 | 553115 | RNAseq | 0.1488 | 0.2700 | |
| SRP159526 | PEF1 | 553115 | RNAseq | 0.8659 | 0.1373 | |
| SRP193095 | PEF1 | 553115 | RNAseq | 0.0337 | 0.7687 | |
| SRP219564 | PEF1 | 553115 | RNAseq | -0.0449 | 0.8744 | |
| TCGA | PEF1 | 553115 | RNAseq | 0.0557 | 0.2546 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PEF1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PEF1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PEF1 | 553115 | 1 | 5 | 24 | |
| GSE20123 | PEF1 | 553115 | 1 | 4 | 25 | |
| GSE43470 | PEF1 | 553115 | 6 | 4 | 33 | |
| GSE46452 | PEF1 | 553115 | 5 | 1 | 53 | |
| GSE47630 | PEF1 | 553115 | 8 | 3 | 29 | |
| GSE54993 | PEF1 | 553115 | 1 | 1 | 68 | |
| GSE54994 | PEF1 | 553115 | 11 | 2 | 40 | |
| GSE60625 | PEF1 | 553115 | 0 | 0 | 11 | |
| GSE74703 | PEF1 | 553115 | 4 | 3 | 29 | |
| GSE74704 | PEF1 | 553115 | 0 | 0 | 20 | |
| TCGA | PEF1 | 553115 | 12 | 19 | 65 |
Total number of gains: 49; Total number of losses: 42; Total Number of normals: 397.
Somatic mutations of PEF1:
Generating mutation plots.
Highly correlated genes for PEF1:
Showing top 20/82 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PEF1 | CORT | 0.700798 | 4 | 0 | 4 |
| PEF1 | GPR26 | 0.687184 | 3 | 0 | 3 |
| PEF1 | TLR9 | 0.646225 | 3 | 0 | 3 |
| PEF1 | KCNN4 | 0.631295 | 3 | 0 | 3 |
| PEF1 | IFT27 | 0.630274 | 5 | 0 | 4 |
| PEF1 | GEMIN2 | 0.629617 | 3 | 0 | 3 |
| PEF1 | SNRNP40 | 0.619315 | 7 | 0 | 5 |
| PEF1 | TMCC2 | 0.616431 | 4 | 0 | 4 |
| PEF1 | ETFB | 0.615884 | 3 | 0 | 3 |
| PEF1 | TUT1 | 0.614624 | 4 | 0 | 3 |
| PEF1 | POLL | 0.610565 | 3 | 0 | 3 |
| PEF1 | ENO1 | 0.607231 | 7 | 0 | 6 |
| PEF1 | ASTN2 | 0.602135 | 4 | 0 | 3 |
| PEF1 | NFYC | 0.60203 | 4 | 0 | 3 |
| PEF1 | BTBD3 | 0.601697 | 3 | 0 | 3 |
| PEF1 | SNHG19 | 0.599236 | 3 | 0 | 3 |
| PEF1 | TFPT | 0.590783 | 6 | 0 | 3 |
| PEF1 | LTBP3 | 0.588574 | 5 | 0 | 3 |
| PEF1 | IER5L | 0.587175 | 3 | 0 | 3 |
| PEF1 | NTMT1 | 0.585676 | 3 | 0 | 3 |
For details and further investigation, click here
