| Full name: Wnt family member 11 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 11q13.5 | ||
| Entrez ID: 7481 | HGNC ID: HGNC:12776 | Ensembl Gene: ENSG00000085741 | OMIM ID: 603699 |
| Drug and gene relationship at DGIdb | |||
WNT11 involved pathways:
Expression of WNT11:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | WNT11 | 7481 | 206737_at | 0.4736 | 0.3168 | |
| GSE20347 | WNT11 | 7481 | 206737_at | 0.3159 | 0.0123 | |
| GSE23400 | WNT11 | 7481 | 206737_at | 0.0103 | 0.8760 | |
| GSE26886 | WNT11 | 7481 | 206737_at | 0.6482 | 0.0127 | |
| GSE29001 | WNT11 | 7481 | 206737_at | 0.4178 | 0.4551 | |
| GSE38129 | WNT11 | 7481 | 206737_at | 0.2248 | 0.1976 | |
| GSE45670 | WNT11 | 7481 | 206737_at | 0.1342 | 0.5545 | |
| GSE53622 | WNT11 | 7481 | 25796 | 0.9784 | 0.0004 | |
| GSE53624 | WNT11 | 7481 | 25796 | 1.4458 | 0.0000 | |
| GSE63941 | WNT11 | 7481 | 206737_at | 0.6093 | 0.1273 | |
| GSE77861 | WNT11 | 7481 | 206737_at | -0.0827 | 0.5131 | |
| GSE97050 | WNT11 | 7481 | A_24_P253003 | 0.3791 | 0.4932 | |
| SRP064894 | WNT11 | 7481 | RNAseq | 1.0664 | 0.0054 | |
| SRP133303 | WNT11 | 7481 | RNAseq | -0.9113 | 0.0546 | |
| SRP219564 | WNT11 | 7481 | RNAseq | 1.0181 | 0.2808 | |
| TCGA | WNT11 | 7481 | RNAseq | 0.9415 | 0.0063 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by WNT11 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of WNT11:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | WNT11 | 7481 | 6 | 8 | 16 | |
| GSE20123 | WNT11 | 7481 | 6 | 7 | 17 | |
| GSE43470 | WNT11 | 7481 | 3 | 3 | 37 | |
| GSE46452 | WNT11 | 7481 | 7 | 22 | 30 | |
| GSE47630 | WNT11 | 7481 | 5 | 16 | 19 | |
| GSE54993 | WNT11 | 7481 | 8 | 2 | 60 | |
| GSE54994 | WNT11 | 7481 | 8 | 16 | 29 | |
| GSE60625 | WNT11 | 7481 | 4 | 3 | 4 | |
| GSE74703 | WNT11 | 7481 | 2 | 2 | 32 | |
| GSE74704 | WNT11 | 7481 | 4 | 3 | 13 | |
| TCGA | WNT11 | 7481 | 20 | 31 | 45 |
Total number of gains: 73; Total number of losses: 113; Total Number of normals: 302.
Somatic mutations of WNT11:
Generating mutation plots.
Highly correlated genes for WNT11:
Showing top 20/76 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| WNT11 | GPC1 | 0.669821 | 3 | 0 | 3 |
| WNT11 | ELOVL7 | 0.663864 | 3 | 0 | 3 |
| WNT11 | IGFBPL1 | 0.650138 | 4 | 0 | 3 |
| WNT11 | MPV17L | 0.647947 | 3 | 0 | 3 |
| WNT11 | STXBP5L | 0.625866 | 3 | 0 | 3 |
| WNT11 | MICALCL | 0.623873 | 3 | 0 | 3 |
| WNT11 | SLC4A2 | 0.623532 | 3 | 0 | 3 |
| WNT11 | SLC16A1-AS1 | 0.622932 | 3 | 0 | 3 |
| WNT11 | C1orf115 | 0.620753 | 3 | 0 | 3 |
| WNT11 | PXK | 0.615683 | 3 | 0 | 3 |
| WNT11 | STXBP1 | 0.608737 | 3 | 0 | 3 |
| WNT11 | POMZP3 | 0.603881 | 4 | 0 | 3 |
| WNT11 | LOR | 0.603578 | 4 | 0 | 3 |
| WNT11 | HOXC10 | 0.603565 | 6 | 0 | 4 |
| WNT11 | HES6 | 0.602226 | 4 | 0 | 3 |
| WNT11 | SDR39U1 | 0.596566 | 3 | 0 | 3 |
| WNT11 | BIN3-IT1 | 0.595742 | 3 | 0 | 3 |
| WNT11 | FZD3 | 0.594972 | 4 | 0 | 3 |
| WNT11 | NLGN4X | 0.589224 | 4 | 0 | 3 |
| WNT11 | PKNOX1 | 0.588716 | 3 | 0 | 3 |
For details and further investigation, click here
