| Full name: podocalyxin like 2 | Alias Symbol: PODLX2|endoglycan | ||
| Type: protein-coding gene | Cytoband: 3q21.3 | ||
| Entrez ID: 50512 | HGNC ID: HGNC:17936 | Ensembl Gene: ENSG00000114631 | OMIM ID: 616627 |
| Drug and gene relationship at DGIdb | |||
Expression of PODXL2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PODXL2 | 50512 | 219152_at | 1.0965 | 0.1977 | |
| GSE20347 | PODXL2 | 50512 | 219152_at | 0.0890 | 0.5706 | |
| GSE23400 | PODXL2 | 50512 | 219152_at | -0.0025 | 0.9554 | |
| GSE26886 | PODXL2 | 50512 | 219152_at | 0.6686 | 0.0003 | |
| GSE29001 | PODXL2 | 50512 | 219152_at | 0.0612 | 0.6329 | |
| GSE38129 | PODXL2 | 50512 | 219152_at | 0.3808 | 0.0174 | |
| GSE45670 | PODXL2 | 50512 | 219152_at | -0.0437 | 0.7617 | |
| GSE53622 | PODXL2 | 50512 | 10314 | -0.1925 | 0.0070 | |
| GSE53624 | PODXL2 | 50512 | 10314 | 0.0101 | 0.8927 | |
| GSE63941 | PODXL2 | 50512 | 219152_at | 0.7323 | 0.1471 | |
| GSE77861 | PODXL2 | 50512 | 219152_at | 0.0197 | 0.9223 | |
| GSE97050 | PODXL2 | 50512 | A_33_P3266780 | 0.6418 | 0.1785 | |
| SRP007169 | PODXL2 | 50512 | RNAseq | 0.3740 | 0.6440 | |
| SRP064894 | PODXL2 | 50512 | RNAseq | 0.3178 | 0.4724 | |
| SRP133303 | PODXL2 | 50512 | RNAseq | 1.1743 | 0.0018 | |
| SRP159526 | PODXL2 | 50512 | RNAseq | 2.6008 | 0.0000 | |
| SRP193095 | PODXL2 | 50512 | RNAseq | 1.0273 | 0.0006 | |
| TCGA | PODXL2 | 50512 | RNAseq | -0.1828 | 0.4073 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by PODXL2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PODXL2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PODXL2 | 50512 | 17 | 0 | 13 | |
| GSE20123 | PODXL2 | 50512 | 17 | 0 | 13 | |
| GSE43470 | PODXL2 | 50512 | 19 | 0 | 24 | |
| GSE46452 | PODXL2 | 50512 | 14 | 5 | 40 | |
| GSE47630 | PODXL2 | 50512 | 17 | 4 | 19 | |
| GSE54993 | PODXL2 | 50512 | 2 | 7 | 61 | |
| GSE54994 | PODXL2 | 50512 | 31 | 3 | 19 | |
| GSE60625 | PODXL2 | 50512 | 0 | 6 | 5 | |
| GSE74703 | PODXL2 | 50512 | 17 | 0 | 19 | |
| GSE74704 | PODXL2 | 50512 | 13 | 0 | 7 | |
| TCGA | PODXL2 | 50512 | 56 | 6 | 34 |
Total number of gains: 203; Total number of losses: 31; Total Number of normals: 254.
Somatic mutations of PODXL2:
Generating mutation plots.
Highly correlated genes for PODXL2:
Showing top 20/235 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PODXL2 | HRK | 0.80856 | 3 | 0 | 3 |
| PODXL2 | GAS6-AS1 | 0.771796 | 3 | 0 | 3 |
| PODXL2 | PDCD11 | 0.771776 | 3 | 0 | 3 |
| PODXL2 | PNLDC1 | 0.750795 | 3 | 0 | 3 |
| PODXL2 | STEAP3 | 0.745258 | 3 | 0 | 3 |
| PODXL2 | NMNAT3 | 0.739743 | 3 | 0 | 3 |
| PODXL2 | BLOC1S3 | 0.737831 | 3 | 0 | 3 |
| PODXL2 | CPSF4 | 0.728635 | 3 | 0 | 3 |
| PODXL2 | POLR3A | 0.696561 | 3 | 0 | 3 |
| PODXL2 | WDR53 | 0.690753 | 3 | 0 | 3 |
| PODXL2 | C18orf21 | 0.68711 | 3 | 0 | 3 |
| PODXL2 | AGO2 | 0.675834 | 3 | 0 | 3 |
| PODXL2 | SURF2 | 0.670065 | 4 | 0 | 3 |
| PODXL2 | RBM28 | 0.665211 | 4 | 0 | 3 |
| PODXL2 | MYBBP1A | 0.664551 | 3 | 0 | 3 |
| PODXL2 | MEX3A | 0.660829 | 7 | 0 | 5 |
| PODXL2 | TSR3 | 0.659326 | 3 | 0 | 3 |
| PODXL2 | GPR162 | 0.65868 | 3 | 0 | 3 |
| PODXL2 | C16orf95 | 0.658679 | 3 | 0 | 3 |
| PODXL2 | RUVBL2 | 0.656047 | 5 | 0 | 4 |
For details and further investigation, click here
