| Full name: interleukin 17 receptor B | Alias Symbol: IL17RH1|EVI27|CRL4 | ||
| Type: protein-coding gene | Cytoband: 3p21.1 | ||
| Entrez ID: 55540 | HGNC ID: HGNC:18015 | Ensembl Gene: ENSG00000056736 | OMIM ID: 605458 |
| Drug and gene relationship at DGIdb | |||
Expression of IL17RB:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | IL17RB | 55540 | 224156_x_at | 0.3219 | 0.3152 | |
| GSE20347 | IL17RB | 55540 | 219255_x_at | 0.3106 | 0.0658 | |
| GSE23400 | IL17RB | 55540 | 219255_x_at | 0.0109 | 0.8841 | |
| GSE26886 | IL17RB | 55540 | 224156_x_at | 0.0631 | 0.7988 | |
| GSE29001 | IL17RB | 55540 | 219255_x_at | 0.5212 | 0.2328 | |
| GSE38129 | IL17RB | 55540 | 219255_x_at | 0.3024 | 0.1021 | |
| GSE45670 | IL17RB | 55540 | 224361_s_at | 0.2628 | 0.1040 | |
| GSE53622 | IL17RB | 55540 | 37052 | -0.2952 | 0.0612 | |
| GSE53624 | IL17RB | 55540 | 37052 | -0.0353 | 0.8279 | |
| GSE63941 | IL17RB | 55540 | 224361_s_at | 0.5114 | 0.4439 | |
| GSE77861 | IL17RB | 55540 | 224156_x_at | 0.0633 | 0.6333 | |
| GSE97050 | IL17RB | 55540 | A_24_P157370 | 0.1761 | 0.7255 | |
| SRP007169 | IL17RB | 55540 | RNAseq | 0.9501 | 0.2461 | |
| SRP064894 | IL17RB | 55540 | RNAseq | 0.1254 | 0.5610 | |
| SRP133303 | IL17RB | 55540 | RNAseq | 0.0846 | 0.6725 | |
| SRP193095 | IL17RB | 55540 | RNAseq | -0.0345 | 0.9070 | |
| SRP219564 | IL17RB | 55540 | RNAseq | 0.4200 | 0.4750 | |
| TCGA | IL17RB | 55540 | RNAseq | -0.6718 | 0.0007 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by IL17RB expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of IL17RB:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | IL17RB | 55540 | 0 | 17 | 13 | |
| GSE20123 | IL17RB | 55540 | 0 | 18 | 12 | |
| GSE43470 | IL17RB | 55540 | 0 | 18 | 25 | |
| GSE46452 | IL17RB | 55540 | 2 | 17 | 40 | |
| GSE47630 | IL17RB | 55540 | 1 | 24 | 15 | |
| GSE54993 | IL17RB | 55540 | 6 | 2 | 62 | |
| GSE54994 | IL17RB | 55540 | 0 | 32 | 21 | |
| GSE60625 | IL17RB | 55540 | 5 | 0 | 6 | |
| GSE74703 | IL17RB | 55540 | 0 | 14 | 22 | |
| GSE74704 | IL17RB | 55540 | 0 | 12 | 8 | |
| TCGA | IL17RB | 55540 | 0 | 79 | 17 |
Total number of gains: 14; Total number of losses: 233; Total Number of normals: 241.
Somatic mutations of IL17RB:
Generating mutation plots.
Highly correlated genes for IL17RB:
Showing top 20/63 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| IL17RB | ANKH | 0.713633 | 3 | 0 | 3 |
| IL17RB | LINC00965 | 0.694393 | 3 | 0 | 3 |
| IL17RB | FRS3 | 0.632031 | 3 | 0 | 3 |
| IL17RB | AMDHD1 | 0.621483 | 3 | 0 | 3 |
| IL17RB | USP18 | 0.615841 | 4 | 0 | 3 |
| IL17RB | TJAP1 | 0.614708 | 3 | 0 | 3 |
| IL17RB | PADI2 | 0.612194 | 8 | 0 | 6 |
| IL17RB | ASB4 | 0.609973 | 4 | 0 | 3 |
| IL17RB | TRIM45 | 0.609503 | 3 | 0 | 3 |
| IL17RB | PABPC4L | 0.608995 | 5 | 0 | 3 |
| IL17RB | SV2B | 0.606166 | 4 | 0 | 4 |
| IL17RB | RBM14 | 0.603822 | 3 | 0 | 3 |
| IL17RB | PLCXD1 | 0.593624 | 3 | 0 | 3 |
| IL17RB | PHKA2 | 0.58759 | 4 | 0 | 4 |
| IL17RB | DROSHA | 0.587042 | 5 | 0 | 4 |
| IL17RB | TAF4B | 0.584203 | 5 | 0 | 3 |
| IL17RB | LINC00240 | 0.582069 | 4 | 0 | 3 |
| IL17RB | DMWD | 0.581488 | 4 | 0 | 3 |
| IL17RB | BCL2L14 | 0.580449 | 7 | 0 | 3 |
| IL17RB | ATP8A2 | 0.572359 | 5 | 0 | 4 |
For details and further investigation, click here
