| Full name: peptidyl arginine deiminase 2 | Alias Symbol: KIAA0994|PDI2 | ||
| Type: protein-coding gene | Cytoband: 1p36.13 | ||
| Entrez ID: 11240 | HGNC ID: HGNC:18341 | Ensembl Gene: ENSG00000117115 | OMIM ID: 607935 |
| Drug and gene relationship at DGIdb | |||
Expression of PADI2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PADI2 | 11240 | 209791_at | 0.4366 | 0.5545 | |
| GSE20347 | PADI2 | 11240 | 209791_at | 0.1959 | 0.2443 | |
| GSE23400 | PADI2 | 11240 | 209791_at | -0.0103 | 0.8550 | |
| GSE26886 | PADI2 | 11240 | 209791_at | 0.3588 | 0.0708 | |
| GSE29001 | PADI2 | 11240 | 209791_at | 0.1513 | 0.7009 | |
| GSE38129 | PADI2 | 11240 | 209791_at | 0.0795 | 0.5610 | |
| GSE45670 | PADI2 | 11240 | 209791_at | -0.0077 | 0.9496 | |
| GSE53622 | PADI2 | 11240 | 1093 | -0.0439 | 0.8400 | |
| GSE53624 | PADI2 | 11240 | 1093 | -0.3594 | 0.0065 | |
| GSE63941 | PADI2 | 11240 | 209791_at | 0.9018 | 0.2167 | |
| GSE77861 | PADI2 | 11240 | 209791_at | 0.0552 | 0.6858 | |
| GSE97050 | PADI2 | 11240 | A_23_P201747 | -0.2362 | 0.4297 | |
| SRP007169 | PADI2 | 11240 | RNAseq | 0.7041 | 0.3582 | |
| SRP064894 | PADI2 | 11240 | RNAseq | -0.4588 | 0.1446 | |
| SRP133303 | PADI2 | 11240 | RNAseq | -0.0487 | 0.8961 | |
| SRP193095 | PADI2 | 11240 | RNAseq | -0.0556 | 0.8611 | |
| SRP219564 | PADI2 | 11240 | RNAseq | 0.0670 | 0.9226 | |
| TCGA | PADI2 | 11240 | RNAseq | 0.2421 | 0.3892 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PADI2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PADI2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PADI2 | 11240 | 0 | 5 | 25 | |
| GSE20123 | PADI2 | 11240 | 0 | 4 | 26 | |
| GSE43470 | PADI2 | 11240 | 0 | 8 | 35 | |
| GSE46452 | PADI2 | 11240 | 5 | 1 | 53 | |
| GSE47630 | PADI2 | 11240 | 8 | 3 | 29 | |
| GSE54993 | PADI2 | 11240 | 3 | 1 | 66 | |
| GSE54994 | PADI2 | 11240 | 10 | 4 | 39 | |
| GSE60625 | PADI2 | 11240 | 0 | 0 | 11 | |
| GSE74703 | PADI2 | 11240 | 0 | 5 | 31 | |
| GSE74704 | PADI2 | 11240 | 0 | 0 | 20 | |
| TCGA | PADI2 | 11240 | 9 | 22 | 65 |
Total number of gains: 35; Total number of losses: 53; Total Number of normals: 400.
Somatic mutations of PADI2:
Generating mutation plots.
Highly correlated genes for PADI2:
Showing top 20/59 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PADI2 | TGIF2 | 0.672531 | 3 | 0 | 3 |
| PADI2 | INHBB | 0.642238 | 3 | 0 | 3 |
| PADI2 | CCHCR1 | 0.634811 | 5 | 0 | 4 |
| PADI2 | ANKRD23 | 0.633758 | 3 | 0 | 3 |
| PADI2 | MYO7A | 0.633528 | 4 | 0 | 3 |
| PADI2 | ZBTB39 | 0.628284 | 3 | 0 | 3 |
| PADI2 | CUZD1 | 0.614964 | 3 | 0 | 3 |
| PADI2 | MED13 | 0.612987 | 3 | 0 | 3 |
| PADI2 | IL17RB | 0.612194 | 8 | 0 | 6 |
| PADI2 | KRT81 | 0.607835 | 5 | 0 | 3 |
| PADI2 | SIGIRR | 0.602386 | 3 | 0 | 3 |
| PADI2 | GFRA1 | 0.600039 | 5 | 0 | 3 |
| PADI2 | LZTS3 | 0.592586 | 3 | 0 | 3 |
| PADI2 | SOX10 | 0.592546 | 4 | 0 | 3 |
| PADI2 | CABLES2 | 0.590367 | 3 | 0 | 3 |
| PADI2 | ENTPD6 | 0.588183 | 4 | 0 | 3 |
| PADI2 | CD70 | 0.587105 | 4 | 0 | 3 |
| PADI2 | MIA | 0.58516 | 8 | 0 | 5 |
| PADI2 | MYBPC1 | 0.583794 | 6 | 0 | 3 |
| PADI2 | SFI1 | 0.57825 | 4 | 0 | 3 |
For details and further investigation, click here
