| Full name: ANKH inorganic pyrophosphate transport regulator | Alias Symbol: HANK|ANK|CPPDD|SLC62A1 | ||
| Type: protein-coding gene | Cytoband: 5p15.2 | ||
| Entrez ID: 56172 | HGNC ID: HGNC:15492 | Ensembl Gene: ENSG00000154122 | OMIM ID: 605145 |
| Drug and gene relationship at DGIdb | |||
Expression of ANKH:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ANKH | 56172 | 223092_at | 0.2977 | 0.7491 | |
| GSE20347 | ANKH | 56172 | 220076_at | -0.0020 | 0.9891 | |
| GSE23400 | ANKH | 56172 | 220076_at | 0.0674 | 0.0277 | |
| GSE26886 | ANKH | 56172 | 223092_at | 0.5234 | 0.2117 | |
| GSE29001 | ANKH | 56172 | 220076_at | 0.1956 | 0.6458 | |
| GSE38129 | ANKH | 56172 | 220076_at | -0.1448 | 0.3270 | |
| GSE45670 | ANKH | 56172 | 223092_at | -0.0230 | 0.9585 | |
| GSE53622 | ANKH | 56172 | 61204 | 0.1613 | 0.2488 | |
| GSE53624 | ANKH | 56172 | 61204 | 0.2376 | 0.0224 | |
| GSE63941 | ANKH | 56172 | 223092_at | -1.1740 | 0.1027 | |
| GSE77861 | ANKH | 56172 | 223092_at | 0.2941 | 0.4328 | |
| GSE97050 | ANKH | 56172 | A_24_P371628 | 0.2432 | 0.3313 | |
| SRP007169 | ANKH | 56172 | RNAseq | 0.5868 | 0.0870 | |
| SRP008496 | ANKH | 56172 | RNAseq | 0.7419 | 0.0040 | |
| SRP064894 | ANKH | 56172 | RNAseq | 0.5289 | 0.0013 | |
| SRP133303 | ANKH | 56172 | RNAseq | 0.3710 | 0.1827 | |
| SRP159526 | ANKH | 56172 | RNAseq | 0.2217 | 0.3214 | |
| SRP193095 | ANKH | 56172 | RNAseq | 0.3623 | 0.0025 | |
| SRP219564 | ANKH | 56172 | RNAseq | 0.3233 | 0.4691 | |
| TCGA | ANKH | 56172 | RNAseq | 0.0259 | 0.7319 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ANKH expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ANKH:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ANKH | 56172 | 12 | 0 | 18 | |
| GSE20123 | ANKH | 56172 | 12 | 0 | 18 | |
| GSE43470 | ANKH | 56172 | 16 | 0 | 27 | |
| GSE46452 | ANKH | 56172 | 6 | 22 | 31 | |
| GSE47630 | ANKH | 56172 | 6 | 11 | 23 | |
| GSE54993 | ANKH | 56172 | 5 | 5 | 60 | |
| GSE54994 | ANKH | 56172 | 29 | 2 | 22 | |
| GSE60625 | ANKH | 56172 | 0 | 0 | 11 | |
| GSE74703 | ANKH | 56172 | 13 | 0 | 23 | |
| GSE74704 | ANKH | 56172 | 11 | 0 | 9 | |
| TCGA | ANKH | 56172 | 59 | 3 | 34 |
Total number of gains: 169; Total number of losses: 43; Total Number of normals: 276.
Somatic mutations of ANKH:
Generating mutation plots.
Highly correlated genes for ANKH:
Showing top 20/35 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ANKH | IL17RB | 0.713633 | 3 | 0 | 3 |
| ANKH | LAYN | 0.665523 | 3 | 0 | 3 |
| ANKH | TTYH2 | 0.650234 | 3 | 0 | 3 |
| ANKH | CBX2 | 0.630098 | 3 | 0 | 3 |
| ANKH | LEPR | 0.620303 | 3 | 0 | 3 |
| ANKH | TBC1D1 | 0.606556 | 4 | 0 | 3 |
| ANKH | TBC1D2B | 0.604286 | 3 | 0 | 3 |
| ANKH | SNRNP40 | 0.602122 | 3 | 0 | 3 |
| ANKH | C12orf76 | 0.601233 | 3 | 0 | 3 |
| ANKH | LINC00965 | 0.6008 | 3 | 0 | 3 |
| ANKH | IGFBP3 | 0.596886 | 3 | 0 | 3 |
| ANKH | CTSK | 0.575604 | 4 | 0 | 3 |
| ANKH | ITGA4 | 0.574631 | 4 | 0 | 3 |
| ANKH | HTRA1 | 0.564331 | 6 | 0 | 3 |
| ANKH | SUPT16H | 0.563601 | 3 | 0 | 3 |
| ANKH | C3orf70 | 0.560373 | 3 | 0 | 3 |
| ANKH | PCOLCE | 0.556878 | 3 | 0 | 3 |
| ANKH | PRKCQ | 0.548861 | 5 | 0 | 4 |
| ANKH | FBXL7 | 0.548164 | 3 | 0 | 3 |
| ANKH | FEZ1 | 0.543218 | 5 | 0 | 3 |
For details and further investigation, click here
