| Full name: interleukin 1 receptor like 2 | Alias Symbol: IL1R-rp2|IL1RRP2 | ||
| Type: protein-coding gene | Cytoband: 2q12.1 | ||
| Entrez ID: 8808 | HGNC ID: HGNC:5999 | Ensembl Gene: ENSG00000115598 | OMIM ID: 604512 |
| Drug and gene relationship at DGIdb | |||
Expression of IL1RL2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | IL1RL2 | 8808 | 208038_at | 0.0963 | 0.9082 | |
| GSE20347 | IL1RL2 | 8808 | 208038_at | -0.4083 | 0.0004 | |
| GSE23400 | IL1RL2 | 8808 | 208038_at | -0.4183 | 0.0000 | |
| GSE26886 | IL1RL2 | 8808 | 208038_at | -0.2451 | 0.1684 | |
| GSE29001 | IL1RL2 | 8808 | 208038_at | -0.2826 | 0.0502 | |
| GSE38129 | IL1RL2 | 8808 | 208038_at | -0.3970 | 0.0027 | |
| GSE45670 | IL1RL2 | 8808 | 208038_at | 0.0629 | 0.7743 | |
| GSE53622 | IL1RL2 | 8808 | 92323 | -0.5648 | 0.0003 | |
| GSE53624 | IL1RL2 | 8808 | 92323 | -0.7326 | 0.0000 | |
| GSE63941 | IL1RL2 | 8808 | 208038_at | 0.3203 | 0.4254 | |
| GSE77861 | IL1RL2 | 8808 | 208038_at | -0.3048 | 0.1021 | |
| GSE97050 | IL1RL2 | 8808 | A_23_P56604 | 0.3462 | 0.3656 | |
| SRP007169 | IL1RL2 | 8808 | RNAseq | -3.0332 | 0.0000 | |
| SRP064894 | IL1RL2 | 8808 | RNAseq | -1.4490 | 0.0000 | |
| SRP133303 | IL1RL2 | 8808 | RNAseq | -1.1326 | 0.0000 | |
| SRP159526 | IL1RL2 | 8808 | RNAseq | -1.8106 | 0.0003 | |
| SRP193095 | IL1RL2 | 8808 | RNAseq | -1.3873 | 0.0000 | |
| SRP219564 | IL1RL2 | 8808 | RNAseq | -1.3787 | 0.0626 | |
| TCGA | IL1RL2 | 8808 | RNAseq | 0.6527 | 0.0010 |
Upregulated datasets: 0; Downregulated datasets: 5.
Survival by IL1RL2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of IL1RL2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | IL1RL2 | 8808 | 5 | 2 | 23 | |
| GSE20123 | IL1RL2 | 8808 | 5 | 2 | 23 | |
| GSE43470 | IL1RL2 | 8808 | 5 | 1 | 37 | |
| GSE46452 | IL1RL2 | 8808 | 1 | 4 | 54 | |
| GSE47630 | IL1RL2 | 8808 | 7 | 0 | 33 | |
| GSE54993 | IL1RL2 | 8808 | 0 | 6 | 64 | |
| GSE54994 | IL1RL2 | 8808 | 11 | 0 | 42 | |
| GSE60625 | IL1RL2 | 8808 | 0 | 3 | 8 | |
| GSE74703 | IL1RL2 | 8808 | 5 | 1 | 30 | |
| GSE74704 | IL1RL2 | 8808 | 3 | 1 | 16 | |
| TCGA | IL1RL2 | 8808 | 34 | 6 | 56 |
Total number of gains: 76; Total number of losses: 26; Total Number of normals: 386.
Somatic mutations of IL1RL2:
Generating mutation plots.
Highly correlated genes for IL1RL2:
Showing top 20/764 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| IL1RL2 | RNF149 | 0.776268 | 3 | 0 | 3 |
| IL1RL2 | SLC31A1 | 0.730084 | 3 | 0 | 3 |
| IL1RL2 | IPMK | 0.711294 | 3 | 0 | 3 |
| IL1RL2 | SLC10A7 | 0.694178 | 3 | 0 | 3 |
| IL1RL2 | SULT2B1 | 0.692182 | 6 | 0 | 6 |
| IL1RL2 | NUAK2 | 0.69008 | 3 | 0 | 3 |
| IL1RL2 | JARID2 | 0.684112 | 4 | 0 | 3 |
| IL1RL2 | IL22RA1 | 0.677166 | 6 | 0 | 6 |
| IL1RL2 | ANKHD1 | 0.669309 | 3 | 0 | 3 |
| IL1RL2 | STXBP5 | 0.662074 | 5 | 0 | 4 |
| IL1RL2 | LYPLA1 | 0.660857 | 6 | 0 | 4 |
| IL1RL2 | NIPAL1 | 0.655038 | 4 | 0 | 3 |
| IL1RL2 | SLC27A4 | 0.650998 | 5 | 0 | 5 |
| IL1RL2 | KCTD11 | 0.648599 | 3 | 0 | 3 |
| IL1RL2 | C3orf38 | 0.643111 | 3 | 0 | 3 |
| IL1RL2 | GLTP | 0.640506 | 7 | 0 | 7 |
| IL1RL2 | TGM1 | 0.640443 | 10 | 0 | 9 |
| IL1RL2 | ZNF675 | 0.638337 | 3 | 0 | 3 |
| IL1RL2 | ORMDL2 | 0.63803 | 7 | 0 | 7 |
| IL1RL2 | PRDM1 | 0.634462 | 9 | 0 | 8 |
For details and further investigation, click here
