| Full name: solute carrier family 31 member 1 | Alias Symbol: hCTR1|CTR1 | ||
| Type: protein-coding gene | Cytoband: 9q32 | ||
| Entrez ID: 1317 | HGNC ID: HGNC:11016 | Ensembl Gene: ENSG00000136868 | OMIM ID: 603085 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of SLC31A1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC31A1 | 1317 | 203971_at | 0.2769 | 0.6702 | |
| GSE20347 | SLC31A1 | 1317 | 203971_at | 0.0375 | 0.8660 | |
| GSE23400 | SLC31A1 | 1317 | 203971_at | 0.2900 | 0.0000 | |
| GSE26886 | SLC31A1 | 1317 | 203971_at | 0.0033 | 0.9888 | |
| GSE29001 | SLC31A1 | 1317 | 203971_at | 0.4055 | 0.3040 | |
| GSE38129 | SLC31A1 | 1317 | 203971_at | 0.3868 | 0.0208 | |
| GSE45670 | SLC31A1 | 1317 | 203971_at | 0.5919 | 0.0003 | |
| GSE53622 | SLC31A1 | 1317 | 9675 | 0.0947 | 0.2115 | |
| GSE53624 | SLC31A1 | 1317 | 9675 | 0.0335 | 0.6579 | |
| GSE63941 | SLC31A1 | 1317 | 203971_at | -0.3771 | 0.2650 | |
| GSE77861 | SLC31A1 | 1317 | 235013_at | -0.2386 | 0.2525 | |
| GSE97050 | SLC31A1 | 1317 | A_24_P321068 | 0.1625 | 0.6673 | |
| SRP007169 | SLC31A1 | 1317 | RNAseq | -0.2044 | 0.5750 | |
| SRP008496 | SLC31A1 | 1317 | RNAseq | -0.2137 | 0.4635 | |
| SRP064894 | SLC31A1 | 1317 | RNAseq | 0.1413 | 0.4741 | |
| SRP133303 | SLC31A1 | 1317 | RNAseq | 0.1584 | 0.2633 | |
| SRP159526 | SLC31A1 | 1317 | RNAseq | 0.1391 | 0.6318 | |
| SRP193095 | SLC31A1 | 1317 | RNAseq | -0.4460 | 0.0035 | |
| SRP219564 | SLC31A1 | 1317 | RNAseq | 0.3264 | 0.4124 | |
| TCGA | SLC31A1 | 1317 | RNAseq | -0.1159 | 0.0296 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SLC31A1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC31A1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC31A1 | 1317 | 5 | 10 | 15 | |
| GSE20123 | SLC31A1 | 1317 | 5 | 10 | 15 | |
| GSE43470 | SLC31A1 | 1317 | 4 | 3 | 36 | |
| GSE46452 | SLC31A1 | 1317 | 6 | 13 | 40 | |
| GSE47630 | SLC31A1 | 1317 | 3 | 16 | 21 | |
| GSE54993 | SLC31A1 | 1317 | 3 | 3 | 64 | |
| GSE54994 | SLC31A1 | 1317 | 9 | 10 | 34 | |
| GSE60625 | SLC31A1 | 1317 | 0 | 0 | 11 | |
| GSE74703 | SLC31A1 | 1317 | 4 | 3 | 29 | |
| GSE74704 | SLC31A1 | 1317 | 2 | 8 | 10 | |
| TCGA | SLC31A1 | 1317 | 26 | 22 | 48 |
Total number of gains: 67; Total number of losses: 98; Total Number of normals: 323.
Somatic mutations of SLC31A1:
Generating mutation plots.
Highly correlated genes for SLC31A1:
Showing top 20/316 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC31A1 | ANKRD13C | 0.738938 | 3 | 0 | 3 |
| SLC31A1 | RASGRP1 | 0.731032 | 3 | 0 | 3 |
| SLC31A1 | IL1RL2 | 0.730084 | 3 | 0 | 3 |
| SLC31A1 | ZNF101 | 0.729502 | 3 | 0 | 3 |
| SLC31A1 | SPAG1 | 0.726765 | 3 | 0 | 3 |
| SLC31A1 | NDFIP2 | 0.724828 | 3 | 0 | 3 |
| SLC31A1 | NABP1 | 0.721695 | 3 | 0 | 3 |
| SLC31A1 | EIF4E | 0.721568 | 4 | 0 | 3 |
| SLC31A1 | BLOC1S2 | 0.70091 | 3 | 0 | 3 |
| SLC31A1 | TMEM167A | 0.697973 | 4 | 0 | 3 |
| SLC31A1 | GRPEL2 | 0.690414 | 3 | 0 | 3 |
| SLC31A1 | WDR11 | 0.673872 | 3 | 0 | 3 |
| SLC31A1 | MITD1 | 0.672102 | 4 | 0 | 3 |
| SLC31A1 | TMCO1 | 0.669826 | 5 | 0 | 4 |
| SLC31A1 | TTC39B | 0.668437 | 4 | 0 | 3 |
| SLC31A1 | PPP4R2 | 0.665766 | 4 | 0 | 3 |
| SLC31A1 | TMEM14B | 0.663029 | 3 | 0 | 3 |
| SLC31A1 | C9orf64 | 0.662559 | 3 | 0 | 3 |
| SLC31A1 | AP1G1 | 0.661387 | 4 | 0 | 3 |
| SLC31A1 | USP32 | 0.659196 | 5 | 0 | 5 |
For details and further investigation, click here
