| Full name: interleukin 20 receptor subunit alpha | Alias Symbol: ZCYTOR7|IL-20R1 | ||
| Type: protein-coding gene | Cytoband: 6q23.3 | ||
| Entrez ID: 53832 | HGNC ID: HGNC:6003 | Ensembl Gene: ENSG00000016402 | OMIM ID: 605620 |
| Drug and gene relationship at DGIdb | |||
IL20RA involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04630 | Jak-STAT signaling pathway |
Expression of IL20RA:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | IL20RA | 53832 | 219115_s_at | 0.0139 | 0.9867 | |
| GSE20347 | IL20RA | 53832 | 219115_s_at | -0.8078 | 0.0019 | |
| GSE23400 | IL20RA | 53832 | 219115_s_at | -0.1240 | 0.0159 | |
| GSE26886 | IL20RA | 53832 | 219115_s_at | -0.6610 | 0.1057 | |
| GSE29001 | IL20RA | 53832 | 219115_s_at | -0.2597 | 0.4363 | |
| GSE38129 | IL20RA | 53832 | 219115_s_at | -0.5323 | 0.0473 | |
| GSE45670 | IL20RA | 53832 | 222829_s_at | 0.1090 | 0.5695 | |
| GSE53622 | IL20RA | 53832 | 87840 | -0.7128 | 0.0002 | |
| GSE53624 | IL20RA | 53832 | 87840 | -1.1651 | 0.0000 | |
| GSE63941 | IL20RA | 53832 | 219115_s_at | 0.1999 | 0.8854 | |
| GSE77861 | IL20RA | 53832 | 222829_s_at | 0.0808 | 0.7336 | |
| SRP007169 | IL20RA | 53832 | RNAseq | -0.3746 | 0.5242 | |
| SRP008496 | IL20RA | 53832 | RNAseq | -0.7884 | 0.0487 | |
| SRP064894 | IL20RA | 53832 | RNAseq | -0.7003 | 0.0198 | |
| SRP133303 | IL20RA | 53832 | RNAseq | -0.4108 | 0.0339 | |
| SRP159526 | IL20RA | 53832 | RNAseq | -0.1014 | 0.7481 | |
| SRP193095 | IL20RA | 53832 | RNAseq | -0.8438 | 0.0006 | |
| SRP219564 | IL20RA | 53832 | RNAseq | 0.1078 | 0.8476 | |
| TCGA | IL20RA | 53832 | RNAseq | -0.0900 | 0.6849 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by IL20RA expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of IL20RA:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | IL20RA | 53832 | 4 | 4 | 22 | |
| GSE20123 | IL20RA | 53832 | 3 | 3 | 24 | |
| GSE43470 | IL20RA | 53832 | 5 | 0 | 38 | |
| GSE46452 | IL20RA | 53832 | 3 | 10 | 46 | |
| GSE47630 | IL20RA | 53832 | 9 | 4 | 27 | |
| GSE54993 | IL20RA | 53832 | 3 | 2 | 65 | |
| GSE54994 | IL20RA | 53832 | 8 | 8 | 37 | |
| GSE60625 | IL20RA | 53832 | 0 | 1 | 10 | |
| GSE74703 | IL20RA | 53832 | 4 | 0 | 32 | |
| GSE74704 | IL20RA | 53832 | 1 | 1 | 18 | |
| TCGA | IL20RA | 53832 | 12 | 17 | 67 |
Total number of gains: 52; Total number of losses: 50; Total Number of normals: 386.
Somatic mutations of IL20RA:
Generating mutation plots.
Highly correlated genes for IL20RA:
Showing top 20/64 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| IL20RA | CLCN3 | 0.591112 | 7 | 0 | 6 |
| IL20RA | ILDR1 | 0.589527 | 4 | 0 | 3 |
| IL20RA | ALDH6A1 | 0.578602 | 5 | 0 | 3 |
| IL20RA | OPLAH | 0.575361 | 3 | 0 | 3 |
| IL20RA | BTBD7 | 0.574351 | 4 | 0 | 3 |
| IL20RA | MBNL3 | 0.56537 | 6 | 0 | 3 |
| IL20RA | MBLAC2 | 0.563698 | 4 | 0 | 3 |
| IL20RA | ZNF506 | 0.563179 | 4 | 0 | 3 |
| IL20RA | SNRNP35 | 0.563058 | 4 | 0 | 3 |
| IL20RA | GRAMD1C | 0.554279 | 8 | 0 | 6 |
| IL20RA | ZNF564 | 0.5542 | 3 | 0 | 3 |
| IL20RA | HIBCH | 0.55189 | 5 | 0 | 3 |
| IL20RA | C2orf15 | 0.551709 | 3 | 0 | 3 |
| IL20RA | ZNF180 | 0.548933 | 5 | 0 | 3 |
| IL20RA | NCOA2 | 0.548438 | 5 | 0 | 3 |
| IL20RA | FYCO1 | 0.547981 | 3 | 0 | 3 |
| IL20RA | CD46 | 0.543963 | 5 | 0 | 3 |
| IL20RA | RPUSD4 | 0.543646 | 3 | 0 | 3 |
| IL20RA | PDIK1L | 0.542066 | 5 | 0 | 3 |
| IL20RA | CLCA4 | 0.539459 | 6 | 0 | 3 |
For details and further investigation, click here
