| Full name: zinc finger protein 180 | Alias Symbol: HHZ168 | ||
| Type: protein-coding gene | Cytoband: 19q13.2 | ||
| Entrez ID: 7733 | HGNC ID: HGNC:12970 | Ensembl Gene: ENSG00000167384 | OMIM ID: 606740 |
| Drug and gene relationship at DGIdb | |||
Expression of ZNF180:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZNF180 | 7733 | 219495_s_at | 0.3962 | 0.5282 | |
| GSE20347 | ZNF180 | 7733 | 219495_s_at | 0.1197 | 0.4435 | |
| GSE23400 | ZNF180 | 7733 | 219495_s_at | 0.1335 | 0.0258 | |
| GSE26886 | ZNF180 | 7733 | 219495_s_at | -0.2653 | 0.4340 | |
| GSE29001 | ZNF180 | 7733 | 219495_s_at | 0.3677 | 0.2883 | |
| GSE38129 | ZNF180 | 7733 | 219495_s_at | 0.1148 | 0.2998 | |
| GSE45670 | ZNF180 | 7733 | 219495_s_at | 0.1309 | 0.3679 | |
| GSE53622 | ZNF180 | 7733 | 61982 | -0.3322 | 0.0153 | |
| GSE53624 | ZNF180 | 7733 | 61982 | -0.0568 | 0.7123 | |
| GSE63941 | ZNF180 | 7733 | 219495_s_at | -0.1547 | 0.7104 | |
| GSE77861 | ZNF180 | 7733 | 230065_at | -0.1093 | 0.4095 | |
| GSE97050 | ZNF180 | 7733 | A_23_P89921 | -0.2282 | 0.6139 | |
| SRP007169 | ZNF180 | 7733 | RNAseq | -0.3747 | 0.3687 | |
| SRP008496 | ZNF180 | 7733 | RNAseq | -0.0500 | 0.8764 | |
| SRP064894 | ZNF180 | 7733 | RNAseq | 0.0008 | 0.9970 | |
| SRP133303 | ZNF180 | 7733 | RNAseq | 0.3138 | 0.2439 | |
| SRP159526 | ZNF180 | 7733 | RNAseq | 0.2322 | 0.5083 | |
| SRP193095 | ZNF180 | 7733 | RNAseq | -0.2618 | 0.0287 | |
| SRP219564 | ZNF180 | 7733 | RNAseq | 0.1277 | 0.6365 | |
| TCGA | ZNF180 | 7733 | RNAseq | -0.1224 | 0.0865 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ZNF180 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZNF180:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZNF180 | 7733 | 7 | 5 | 18 | |
| GSE20123 | ZNF180 | 7733 | 6 | 4 | 20 | |
| GSE43470 | ZNF180 | 7733 | 3 | 11 | 29 | |
| GSE46452 | ZNF180 | 7733 | 45 | 1 | 13 | |
| GSE47630 | ZNF180 | 7733 | 8 | 6 | 26 | |
| GSE54993 | ZNF180 | 7733 | 17 | 4 | 49 | |
| GSE54994 | ZNF180 | 7733 | 6 | 12 | 35 | |
| GSE60625 | ZNF180 | 7733 | 9 | 0 | 2 | |
| GSE74703 | ZNF180 | 7733 | 3 | 7 | 26 | |
| GSE74704 | ZNF180 | 7733 | 5 | 2 | 13 | |
| TCGA | ZNF180 | 7733 | 14 | 17 | 65 |
Total number of gains: 123; Total number of losses: 69; Total Number of normals: 296.
Somatic mutations of ZNF180:
Generating mutation plots.
Highly correlated genes for ZNF180:
Showing top 20/255 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZNF180 | MYO5C | 0.722777 | 3 | 0 | 3 |
| ZNF180 | ZBTB44 | 0.714568 | 3 | 0 | 3 |
| ZNF180 | KDM2B | 0.708394 | 3 | 0 | 3 |
| ZNF180 | RASA2 | 0.6872 | 3 | 0 | 3 |
| ZNF180 | INSM1 | 0.673397 | 3 | 0 | 3 |
| ZNF180 | TMCO4 | 0.669577 | 3 | 0 | 3 |
| ZNF180 | SMAD1 | 0.666122 | 3 | 0 | 3 |
| ZNF180 | TFDP1 | 0.661869 | 3 | 0 | 3 |
| ZNF180 | ZNF227 | 0.657471 | 11 | 0 | 9 |
| ZNF180 | IP6K2 | 0.656372 | 3 | 0 | 3 |
| ZNF180 | PEX2 | 0.652916 | 3 | 0 | 3 |
| ZNF180 | TRIM56 | 0.647602 | 4 | 0 | 4 |
| ZNF180 | TMEM168 | 0.642794 | 6 | 0 | 6 |
| ZNF180 | MOSPD2 | 0.639926 | 3 | 0 | 3 |
| ZNF180 | ARHGAP19 | 0.63841 | 4 | 0 | 4 |
| ZNF180 | THUMPD2 | 0.637856 | 4 | 0 | 3 |
| ZNF180 | PPID | 0.636697 | 3 | 0 | 3 |
| ZNF180 | UBTF | 0.635685 | 3 | 0 | 3 |
| ZNF180 | FNBP1L | 0.634559 | 5 | 0 | 4 |
| ZNF180 | BIVM | 0.632865 | 4 | 0 | 4 |
For details and further investigation, click here
