| Full name: GRAM domain containing 1C | Alias Symbol: DKFZp434C0328 | ||
| Type: protein-coding gene | Cytoband: 3q13.31 | ||
| Entrez ID: 54762 | HGNC ID: HGNC:25252 | Ensembl Gene: ENSG00000178075 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of GRAMD1C:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GRAMD1C | 54762 | 219313_at | -0.3905 | 0.6730 | |
| GSE20347 | GRAMD1C | 54762 | 219313_at | -1.3834 | 0.0001 | |
| GSE23400 | GRAMD1C | 54762 | 219313_at | -0.3597 | 0.0000 | |
| GSE26886 | GRAMD1C | 54762 | 219313_at | -1.7851 | 0.0000 | |
| GSE29001 | GRAMD1C | 54762 | 219313_at | -1.5673 | 0.0057 | |
| GSE38129 | GRAMD1C | 54762 | 219313_at | -0.8608 | 0.0363 | |
| GSE45670 | GRAMD1C | 54762 | 219313_at | -0.0054 | 0.9924 | |
| GSE53622 | GRAMD1C | 54762 | 87929 | -0.8696 | 0.0002 | |
| GSE53624 | GRAMD1C | 54762 | 54805 | -1.4831 | 0.0000 | |
| GSE63941 | GRAMD1C | 54762 | 219313_at | 1.6170 | 0.1430 | |
| GSE77861 | GRAMD1C | 54762 | 219313_at | -1.2007 | 0.0393 | |
| GSE97050 | GRAMD1C | 54762 | A_23_P253012 | -0.2531 | 0.6235 | |
| SRP007169 | GRAMD1C | 54762 | RNAseq | -3.1861 | 0.0000 | |
| SRP008496 | GRAMD1C | 54762 | RNAseq | -2.5255 | 0.0000 | |
| SRP064894 | GRAMD1C | 54762 | RNAseq | -1.4801 | 0.0000 | |
| SRP133303 | GRAMD1C | 54762 | RNAseq | -1.0822 | 0.0034 | |
| SRP159526 | GRAMD1C | 54762 | RNAseq | -1.2923 | 0.0265 | |
| SRP193095 | GRAMD1C | 54762 | RNAseq | -1.3656 | 0.0000 | |
| SRP219564 | GRAMD1C | 54762 | RNAseq | -1.6003 | 0.0333 | |
| TCGA | GRAMD1C | 54762 | RNAseq | -0.4869 | 0.0036 |
Upregulated datasets: 0; Downregulated datasets: 12.
Survival by GRAMD1C expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GRAMD1C:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GRAMD1C | 54762 | 16 | 1 | 13 | |
| GSE20123 | GRAMD1C | 54762 | 16 | 1 | 13 | |
| GSE43470 | GRAMD1C | 54762 | 21 | 1 | 21 | |
| GSE46452 | GRAMD1C | 54762 | 13 | 5 | 41 | |
| GSE47630 | GRAMD1C | 54762 | 16 | 6 | 18 | |
| GSE54993 | GRAMD1C | 54762 | 2 | 6 | 62 | |
| GSE54994 | GRAMD1C | 54762 | 29 | 4 | 20 | |
| GSE60625 | GRAMD1C | 54762 | 0 | 6 | 5 | |
| GSE74703 | GRAMD1C | 54762 | 17 | 1 | 18 | |
| GSE74704 | GRAMD1C | 54762 | 12 | 1 | 7 | |
| TCGA | GRAMD1C | 54762 | 52 | 7 | 37 |
Total number of gains: 194; Total number of losses: 39; Total Number of normals: 255.
Somatic mutations of GRAMD1C:
Generating mutation plots.
Highly correlated genes for GRAMD1C:
Showing top 20/1356 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GRAMD1C | FBXO8 | 0.742892 | 4 | 0 | 4 |
| GRAMD1C | MAT2B | 0.738176 | 3 | 0 | 3 |
| GRAMD1C | CAPZA2 | 0.731721 | 3 | 0 | 3 |
| GRAMD1C | ERBB3 | 0.71698 | 12 | 0 | 12 |
| GRAMD1C | PLD1 | 0.715973 | 11 | 0 | 11 |
| GRAMD1C | TAB3 | 0.712651 | 6 | 0 | 5 |
| GRAMD1C | PCGF3 | 0.705265 | 3 | 0 | 3 |
| GRAMD1C | TMEM54 | 0.700351 | 3 | 0 | 3 |
| GRAMD1C | ATP10B | 0.694857 | 9 | 0 | 8 |
| GRAMD1C | ZDHHC13 | 0.694245 | 11 | 0 | 10 |
| GRAMD1C | RAB25 | 0.691957 | 12 | 0 | 11 |
| GRAMD1C | EXOC1 | 0.688903 | 11 | 0 | 11 |
| GRAMD1C | SLC10A5 | 0.688674 | 3 | 0 | 3 |
| GRAMD1C | SCP2 | 0.688294 | 10 | 0 | 10 |
| GRAMD1C | CLCN3 | 0.688192 | 10 | 0 | 9 |
| GRAMD1C | CIPC | 0.687334 | 3 | 0 | 3 |
| GRAMD1C | STYK1 | 0.684867 | 12 | 0 | 11 |
| GRAMD1C | NEBL | 0.680632 | 10 | 0 | 9 |
| GRAMD1C | ARL6 | 0.680555 | 4 | 0 | 4 |
| GRAMD1C | MKRN1 | 0.680222 | 3 | 0 | 3 |
For details and further investigation, click here
