| Full name: chromosome 11 open reading frame 58 | Alias Symbol: SMAP | ||
| Type: protein-coding gene | Cytoband: 11p15.2 | ||
| Entrez ID: 10944 | HGNC ID: HGNC:16990 | Ensembl Gene: ENSG00000110696 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of C11orf58:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | C11orf58 | 10944 | 200084_at | 0.0148 | 0.9701 | |
| GSE20347 | C11orf58 | 10944 | 200084_at | -0.3448 | 0.0350 | |
| GSE23400 | C11orf58 | 10944 | 200084_at | 0.0885 | 0.2133 | |
| GSE26886 | C11orf58 | 10944 | 201784_s_at | 0.1386 | 0.4831 | |
| GSE29001 | C11orf58 | 10944 | 201784_s_at | 0.2121 | 0.6220 | |
| GSE38129 | C11orf58 | 10944 | 200084_at | -0.3025 | 0.0082 | |
| GSE45670 | C11orf58 | 10944 | 200084_at | -0.0644 | 0.5843 | |
| GSE53622 | C11orf58 | 10944 | 16438 | -0.1882 | 0.1264 | |
| GSE53624 | C11orf58 | 10944 | 16438 | 0.2279 | 0.1158 | |
| GSE63941 | C11orf58 | 10944 | 200084_at | -0.1457 | 0.6954 | |
| GSE77861 | C11orf58 | 10944 | 200084_at | 0.1566 | 0.6729 | |
| GSE97050 | C11orf58 | 10944 | A_33_P3309636 | -0.3188 | 0.2460 | |
| SRP007169 | C11orf58 | 10944 | RNAseq | -0.0493 | 0.8767 | |
| SRP008496 | C11orf58 | 10944 | RNAseq | 0.2242 | 0.3508 | |
| SRP064894 | C11orf58 | 10944 | RNAseq | -0.0961 | 0.4867 | |
| SRP133303 | C11orf58 | 10944 | RNAseq | 0.3806 | 0.0891 | |
| SRP159526 | C11orf58 | 10944 | RNAseq | -0.3086 | 0.1827 | |
| SRP193095 | C11orf58 | 10944 | RNAseq | -0.2098 | 0.0237 | |
| SRP219564 | C11orf58 | 10944 | RNAseq | -0.1512 | 0.4078 | |
| TCGA | C11orf58 | 10944 | RNAseq | -0.0236 | 0.5785 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by C11orf58 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of C11orf58:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | C11orf58 | 10944 | 0 | 10 | 20 | |
| GSE20123 | C11orf58 | 10944 | 0 | 10 | 20 | |
| GSE43470 | C11orf58 | 10944 | 1 | 5 | 37 | |
| GSE46452 | C11orf58 | 10944 | 7 | 5 | 47 | |
| GSE47630 | C11orf58 | 10944 | 3 | 10 | 27 | |
| GSE54993 | C11orf58 | 10944 | 3 | 0 | 67 | |
| GSE54994 | C11orf58 | 10944 | 3 | 12 | 38 | |
| GSE60625 | C11orf58 | 10944 | 0 | 0 | 11 | |
| GSE74703 | C11orf58 | 10944 | 1 | 3 | 32 | |
| GSE74704 | C11orf58 | 10944 | 0 | 9 | 11 | |
| TCGA | C11orf58 | 10944 | 11 | 29 | 56 |
Total number of gains: 29; Total number of losses: 93; Total Number of normals: 366.
Somatic mutations of C11orf58:
Generating mutation plots.
Highly correlated genes for C11orf58:
Showing top 20/370 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| C11orf58 | RNF19A | 0.8204 | 3 | 0 | 3 |
| C11orf58 | WWTR1 | 0.748191 | 3 | 0 | 3 |
| C11orf58 | TTC14 | 0.713323 | 3 | 0 | 3 |
| C11orf58 | IMPAD1 | 0.702669 | 4 | 0 | 3 |
| C11orf58 | CIR1 | 0.691137 | 3 | 0 | 3 |
| C11orf58 | TM2D3 | 0.69 | 3 | 0 | 3 |
| C11orf58 | SMAD1 | 0.689964 | 3 | 0 | 3 |
| C11orf58 | NR3C1 | 0.689058 | 4 | 0 | 3 |
| C11orf58 | RBM34 | 0.68242 | 4 | 0 | 3 |
| C11orf58 | TSPAN31 | 0.681468 | 3 | 0 | 3 |
| C11orf58 | CCDC50 | 0.680656 | 3 | 0 | 3 |
| C11orf58 | UXS1 | 0.677874 | 3 | 0 | 3 |
| C11orf58 | CEP70 | 0.676448 | 4 | 0 | 4 |
| C11orf58 | NDUFAF4 | 0.67608 | 5 | 0 | 4 |
| C11orf58 | SH3BGRL | 0.673445 | 4 | 0 | 3 |
| C11orf58 | UBE2G1 | 0.669395 | 3 | 0 | 3 |
| C11orf58 | UBP1 | 0.661579 | 4 | 0 | 3 |
| C11orf58 | RAP1A | 0.661161 | 3 | 0 | 3 |
| C11orf58 | GNE | 0.659264 | 3 | 0 | 3 |
| C11orf58 | SAAL1 | 0.658477 | 4 | 0 | 3 |
For details and further investigation, click here
