| Full name: regulator of microtubule dynamics 1 | Alias Symbol: CGI-90|FLJ20665|RMD1 | ||
| Type: protein-coding gene | Cytoband: 8q21.3 | ||
| Entrez ID: 51115 | HGNC ID: HGNC:24285 | Ensembl Gene: ENSG00000176623 | OMIM ID: 611871 |
| Drug and gene relationship at DGIdb | |||
Expression of RMDN1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RMDN1 | 51115 | 218549_s_at | 0.1229 | 0.8833 | |
| GSE20347 | RMDN1 | 51115 | 218549_s_at | -0.2205 | 0.2749 | |
| GSE23400 | RMDN1 | 51115 | 218549_s_at | 0.1441 | 0.1129 | |
| GSE26886 | RMDN1 | 51115 | 218549_s_at | 0.2401 | 0.1757 | |
| GSE29001 | RMDN1 | 51115 | 218549_s_at | -0.3725 | 0.4980 | |
| GSE38129 | RMDN1 | 51115 | 218549_s_at | 0.0839 | 0.6768 | |
| GSE45670 | RMDN1 | 51115 | 218549_s_at | 0.1817 | 0.2471 | |
| GSE53622 | RMDN1 | 51115 | 68053 | -0.1666 | 0.0119 | |
| GSE53624 | RMDN1 | 51115 | 68053 | -0.2182 | 0.0016 | |
| GSE63941 | RMDN1 | 51115 | 218549_s_at | 0.2258 | 0.6817 | |
| GSE77861 | RMDN1 | 51115 | 218549_s_at | -0.2844 | 0.0768 | |
| SRP007169 | RMDN1 | 51115 | RNAseq | -1.1449 | 0.0006 | |
| SRP008496 | RMDN1 | 51115 | RNAseq | -1.1152 | 0.0000 | |
| SRP064894 | RMDN1 | 51115 | RNAseq | 0.1198 | 0.5312 | |
| SRP133303 | RMDN1 | 51115 | RNAseq | -0.2085 | 0.2048 | |
| SRP159526 | RMDN1 | 51115 | RNAseq | -0.2966 | 0.2259 | |
| SRP193095 | RMDN1 | 51115 | RNAseq | -0.5066 | 0.0000 | |
| SRP219564 | RMDN1 | 51115 | RNAseq | -0.1036 | 0.7692 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by RMDN1 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of RMDN1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RMDN1 | 51115 | 14 | 1 | 15 | |
| GSE20123 | RMDN1 | 51115 | 16 | 1 | 13 | |
| GSE43470 | RMDN1 | 51115 | 19 | 1 | 23 | |
| GSE46452 | RMDN1 | 51115 | 21 | 0 | 38 | |
| GSE47630 | RMDN1 | 51115 | 23 | 0 | 17 | |
| GSE54993 | RMDN1 | 51115 | 0 | 20 | 50 | |
| GSE54994 | RMDN1 | 51115 | 32 | 1 | 20 | |
| GSE60625 | RMDN1 | 51115 | 0 | 4 | 7 | |
| GSE74703 | RMDN1 | 51115 | 16 | 1 | 19 | |
| GSE74704 | RMDN1 | 51115 | 10 | 0 | 10 | |
| TCGA | RMDN1 | 51115 | 54 | 2 | 40 |
Total number of gains: 205; Total number of losses: 31; Total Number of normals: 252.
Somatic mutations of RMDN1:
Generating mutation plots.
Highly correlated genes for RMDN1:
Showing top 20/110 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RMDN1 | N4BP1 | 0.715439 | 4 | 0 | 4 |
| RMDN1 | PPA2 | 0.714514 | 4 | 0 | 4 |
| RMDN1 | ING2 | 0.705103 | 3 | 0 | 3 |
| RMDN1 | SCAMP1 | 0.691358 | 3 | 0 | 3 |
| RMDN1 | PPARD | 0.664954 | 3 | 0 | 3 |
| RMDN1 | CARD18 | 0.648416 | 3 | 0 | 3 |
| RMDN1 | STAU2 | 0.648028 | 4 | 0 | 4 |
| RMDN1 | LYPLA1 | 0.645535 | 7 | 0 | 6 |
| RMDN1 | MTO1 | 0.635569 | 4 | 0 | 3 |
| RMDN1 | SS18 | 0.620155 | 4 | 0 | 3 |
| RMDN1 | MRPL39 | 0.618929 | 3 | 0 | 3 |
| RMDN1 | SH3YL1 | 0.613813 | 3 | 0 | 3 |
| RMDN1 | THOC7 | 0.606166 | 6 | 0 | 5 |
| RMDN1 | SNX16 | 0.605826 | 4 | 0 | 4 |
| RMDN1 | PTGR2 | 0.604601 | 3 | 0 | 3 |
| RMDN1 | RAB22A | 0.604318 | 5 | 0 | 4 |
| RMDN1 | ARPC3 | 0.602336 | 5 | 0 | 4 |
| RMDN1 | RAB2A | 0.599786 | 5 | 0 | 3 |
| RMDN1 | CST6 | 0.599744 | 4 | 0 | 3 |
| RMDN1 | PTP4A1 | 0.597921 | 3 | 0 | 3 |
For details and further investigation, click here
